Intellectual-impairment: Causes & Reasons

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Possible Causes for intellectual impairment

Seckel Syndrome

Abnormality of cognition Cognitive abnormality Cognitive defects Cognitive deficits Intellectual impairment Mental impairment [ more ] 0100543 Convex nasal ridge Beaked nose [rarediseases.info.nih.gov]

Intellectual impairment Mental impairment [ more ] 0100543 Convex nasal ridge Beaked nose Beaklike protrusion Hooked nose Polly beak nasal deformity [ more ] 0000444 Craniosynostosis [rarediseases.info.nih.gov]

Listings in the Blue Book may be consulted during the disability review, including: Section 100.02 – Growth impairment Sections 12.05 or 112.05 – Intellectual disability Section [disabilitybenefitscenter.org]

Trisomy 12p

DEL 1p36 This chromosomal abnormality results in intellectual impairment (moderate to severe), epilepsy and multiple congenital abnormalities. [epilepsydiagnosis.org]

and intellectual disability. [rarediseases.org]

There is developmental delay, severe intellectual impairment and epilepsy. Seizures of varied types have been reported, including epileptic spasms. [epilepsydiagnosis.org]

Cerebellotrigeminal Dermal Dysplasia

impairment, craniosynostosis, short stature, and craniofacial anomalies. [ncbi.nlm.nih.gov]

Other features observed in patients were craniosynostosis, midfacial hypoplasia, bilateral corneal opacities, low-set ears, short stature, moderate intellectual impairment [orpha.net]

Intellectual impairment is typical but cases with normal cognitive functions have also been reported. Only 15 cases of GLHS have been described so far, all sporadic. [ncbi.nlm.nih.gov]

Schindler Disease

Angiokeratomas, an increased coarsening of facial features, and mild intellectual impairment are likely symptoms. Type III is considered an intermediate disorder. [en.wikipedia.org]

impairment, neurological dysfunction and seizures to milder neurological and psychiatric issues such as speech and language delays or mild autism-like symptoms. [orpha.net]

[…] patients with angiokeratoma corporis diffusum and minimal involvement of the nervous system and type 3 is an intermediate clinical form with manifestations ranging from intellectual [orpha.net]

Kanzaki Disease

Format Definition Autosomal recessive disorder characterized by late-onset, angiokeratoma corporis diffusum and mild intellectual impairment. [uniprot.org]

impairment; and type III is an intermediate disorder (see {609241}) with mild to moderate neurologic manifestations ({2:Desnick and Schindler, 2001}). [diseaseinfosearch.org]

The woman had mild intellectual impairment and peripheral neuroaxonal degeneration. [lymphedemapeople.com]

Kohlschütter-Tönz Syndrome

Kohlschutter-Tonz syndrome (KTS; MIM 22675) is a rare autosomal recessive disorder characterized by intellectual impairment, spasticity, epilepsy, and amelogenesis imperfecta [ncbi.nlm.nih.gov]

impairment, spasticity, epilepsy, and amelogenesis imperfecta. [semanticscholar.org]

Rogd... more Kohlschutter-Tonz syndrome (KTS) is a rare genetic disorder with neurological dysfunctions including seizure and intellectual impairment. [scinapse.io]

Intellectual Disability

Code based on degree of severity reflecting level of intellectual impairment: 317 Mild Mental Retardation: IQ level 50-55 to approximately 70 318.0 Moderate Mental Retardation [behavenet.com]

Learning disability aka/or Mental retardation aka/or Oligophrenia aka/or Cognitive development disorder aka/or Educationally sub-normal aka/or ESN aka/or Intellectual impairment [diseasesdatabase.com]

[…] subaverage intellectual functioning). [behavenet.com]

Epidermal Nevus

Angora hair nevus syndrome may be associated with seizures, intellectual impairment, and paralysis of one side of the body (hemiparesis). [rarediseases.org]

Neurological abnormalities include seizures, intellectual impairment, muscle weakness, paralysis on one side of the body (hemiparesis), underdevelopment of one side of the [rarediseases.org]

Neurological abnormalities including seizures, intellectual impairment, degeneration of brain cells (cortical atrophy) and underdevelopment of the area of the brain that connects [rarediseases.org]

Essential Hypertension

Our cases showed arteriolar involvement and clinical symptoms characterized by headaches, dysesthesias, fleeting paralysis, personality changes, intellectual impairment and [annals.org]

Acute Alcohol Intoxication

impairment (i.e. acquired brain injury, mental retardation) Known pregnancy Aggressive behaviour beyond reasonable attempts at de-escalation and deemed a potential threat [ncbi.nlm.nih.gov]

[…] intoxication (no injuries, overdose, or psychiatric conditions requiring ongoing investigation or treatment) Unremarkable physical examination Exclusion criteria Age 50 years Intellectual [ncbi.nlm.nih.gov]

Periventricular Leukomalacia

Periventricular leukomalacia (PVL) occurring in premature infants, represents a major precursor for neurological and intellectual impairment, and cerebral palsy in later life [ncbi.nlm.nih.gov]

OBJECTIVE: Periventricular leukomalacia (PVL) is a neonatal brain white matter injury associated with development of cerebral palsy, intellectual impairment, and visual disturbances [ncbi.nlm.nih.gov]

Damage in this area can result in spasticity and intellectual impairment. [cerebralpalsy.org]

Vitamin B12 Deficiency

[…] deterioration Impotence Paralysis Impaired fine motor coordination Muscular spasticity Bladder or bowel incontinence Impaired pain perception Nocturnal cramping Disturbance [b12deficiency.info]

Balance problems Difficulty walking Dizziness Restless legs Visual disturbances / decreased-blurred vision / damage of optic nerve Forgetfulness, memory loss Dementia / intellectual [b12deficiency.info]

McLeod Neuroacanthocytosis Syndrome

While these behavioral changes are typically not progressive, the movement and muscle problems and intellectual impairments tend to worsen with age. [ghr.nlm.nih.gov]

While these behavioral changes are typically not progressive, the movement problems and intellectual impairments that are characteristic of this condition tend to worsen with [book-med.info]

Muscular Dystrophy

impairment While symptoms vary from mild to severe, the majority of people with congenital muscular dystrophy are unable to sit or stand without help. [healthline.com]

Intellectual impairment may also be present. In Becker muscular dystrophy, weakness may be limited to the quadriceps (muscles in the front of the thigh). [jamanetwork.com]

Some children have severe intellectual impairment, whereas others reach adulthood with only minor disabilities. [nyulangone.org]

Iron Deficiency

Children: tiredness, restlessness, attention-deficit/hyperactivity disorder (ADHD), irritability, growth retardation, cognitive and intellectual impairment. [www2.gov.bc.ca]

The latter include decreased aerobic work performance, hair loss, developmental delay, cognitive and intellectual impairment, adverse pregnancy outcome, and impaired immune [www2.gov.bc.ca]

Hypoglycemia

Recurrent severe hypoglycemic episodes can lead to brain damage and intellectual impairment. [pedclerk.bsd.uchicago.edu]

The potential long-term complications of severe hypoglycemia are mild intellectual impairment and permanent neurologic sequelae, such as hemiparesis and pontine dysfunction [guidelines.diabetes.ca]

Intellectual activity is likely to be affected and cause sub-optimal performance during this recovery period. [doi.org]

BOD Syndrome

Pre- and postnatal short stature, hypoplastic fifth digits with abnormal phalanges and tiny fingernails, facial dysmorphism, and, in some, mild intellectual impairment were [bio2rdf.org]

The complications of BOD Syndrome may include: Emotional stress due facial deformities Involvement of the heart and lungs Intellectual impairment Complications may occur with [dovemed.com]

impairment). [dermatologyadvisor.com]

Sotos Syndrome

Information is provided relating to physical appearance, intellectual impairment, learning disabilities, language impairments, behavioural disorders and outcome. [ncbi.nlm.nih.gov]

It manifests in developmental delay, intellectual impairment, macrocephaly, central nervous system anomalies, postnatal overgrowth, and craniofacial dysmorphism. [ncbi.nlm.nih.gov]

People with Sotos syndrome often have intellectual impairment, and most also have behavioral problems. Problems with speech and language are also common. [diseaseinfosearch.org]

Alcohol Abuse

[…] and mental impairment. [medbroadcast.com]

Moderate amounts of alcohol consumed during pregnancy can lead to the birth of a child with fetal alcohol syndrome (FAS) - a severe neurological syndrome that causes permanent intellectual [medbroadcast.com]

Malnutrition

Impairments in intellectual ability and digestive problems may persist, sometimes throughout life. With treatment, most adults recover fully. [msdmanuals.com]

Dose-dependent relationships between impaired growth and poor school performance and decreased intellectual achievement have been shown. [4, 10, 11, 12] Although death from [emedicine.com]

Behavioral development may be markedly slow, and mild intellectual disability may develop and continue until at least school age. [msdmanuals.com]

Impacted Cerumen

Medical aspects of ageing in a population with intellectual disability: II. Hearing impairment. J Intellect Disabil Res 1995 ; 39 : 27 –33. 32 Rombout J, Van Rijn PM. [academic.oup.com]

which can be deleterious to linguistic, social, and intellectual development.[9] In the UnitedKingdom, some 2.3 million people suffer cerumen problems that are serious enough [nigeriamedj.com]

[…] hearing aids and ear plug user, bony growths such as osteoma as well as abnormally shaped ear canal.[7],[8] Major sequelae of impacted cerumen are conductive hearing loss/impairment [nigeriamedj.com]

Pallister-Killian Syndrome

Pallister-Killian syndrome (PKS) is a rare but distinctive chromosomal syndrome distinguished by severe intellectual impairment, characteristic facial features, and variable [ncbi.nlm.nih.gov]

Pallister-Killian syndrome (PKS) is a multisystem sporadic genetic condition characterized by facial anomalies, variable developmental delay and intellectual impairment, hypotonia [ncbi.nlm.nih.gov]

Clinically, PKS is characterized by several systemic abnormalities, such as intellectual impairment, hearing loss, epilepsy, hypotonia, craniofacial dysmorphism, pigmentary [ncbi.nlm.nih.gov]

Metabolic Syndrome

[…] present from birth or early infancy (learning/intellectual disability, intellectual/developmental impairment) [ IATE:1537659 ]an illness or disorder appearing in later life [gaois.ie]

Meabhairshláinte agus um Fholláine: torthaí agus gníomhaíochtaí amach anseo,' Comhairle an Aontais Eorpaigh, (01)&from GA Comment This broad concept covers both:a disability or impairment [gaois.ie]

Hallervorden-Spatz Syndrome

The presence of mutation in the PANK2 gene is associated with younger age at onset and a higher frequency of dystonia, dysarthria, intellectual impairment, and gait disturbance [ncbi.nlm.nih.gov]

Corroborative findings include corticospinal tract involvement, ie, spasticity and extensor toe signs, progressive intellectual impairment, retinitis pigmentosa and optic [ncbi.nlm.nih.gov]

impairment, and/or pyramidal tract signs. 1 Choreoathetotic movements or tremor may also be present but these features have not been described in isolation. [jnnp.bmj.com]

Duchenne Muscular Dystrophy

All children with DMD will have some degree of intellectual impairment, with most having only learning disabilities. What are the Signs and Symptoms? [nationwidechildrens.org]

Deletion status and intellectual impairment in Duchenne muscular dystrophy. Dev Med Child Neurol. 1995;37:260-269. Barbujani G, Russo A, Danieli GA, et al. [rarediseases.org]

Intellectual impairment may or may not be present but if present, does not progressively worsen as the child ages. [disabled-world.com]

GLUT1 Deficiency Syndrome

It seems more appropriate to think in terms of a broad clinical spectrum in which we can observe intellectual impairment, acquired microcephaly, epilepsy, and movement disorders [ncbi.nlm.nih.gov]

impairment with variable clinical presentation, and without a known genetic cause. [ncbi.nlm.nih.gov]

Reports of intellectual impairment span the spectrum of mental retardation ranging from mild to moderate to severe. [epilepsy.com]

Mucopolysaccharidosis Type 1

impairment. [orpha.net]

[…] diagnosis Mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome; see this term) resembles mucopolysaccharidosis type I in many aspects, MPS VI patients, however, never have intellectual [orpha.net]

Optic Atrophy-Intellectual Disability Syndrome

impairment [genatlas.medecine.univ-paris5.fr]

All affected individuals show mild to moderate intellectual impairment. NR2F1 encodes a nuclear receptor protein that regulates transcription. [ncbi.nlm.nih.gov]

NR2F1 has an important role in the development of the visual system and that haploinsuffiency can lead to optic atrophy with intellectual impairment. [ncbi.nlm.nih.gov]

Worster-Drought Syndrome

Abnormality of cognition Cognitive abnormality Cognitive defects Cognitive deficits Intellectual impairment Mental impairment [ more ] 0100543 Hyperreflexia Increased reflexes [rarediseases.info.nih.gov]

(WDS) is a condition that affects the muscles of the mouth and throat; it is considered a type of cerebral palsy. 0002167 30%-79% of people have these symptoms Cognitive impairment [rarediseases.info.nih.gov]

Chronic Alcoholism

A study of intellectual impairment and recovery rates in heavy drinkers in Ireland. Br. J. Psychiat. 12: 178–184. Google Scholar Coorville, C. B. (1966). [link.springer.com]

There are probably several times as many alcohol-damaged children who have nonspecific symptoms of intellectual impairment and behavioral deficits. 9 Even drinking seven to [aafp.org]