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40 Possible Causes for Interfamilial and Intrafamilial Clinical Heterogeneity, Nystagmus Decreases on Convergence

  • Hereditary Spastic Paraplegia

    The nystagmus diminished briefly after blinks and horizontal saccades, and decreased during eccentric gaze and convergence.[ncbi.nlm.nih.gov] Vibratory stimuli decreased the nystagmus mostly in the left but not in the right eye.[ncbi.nlm.nih.gov] During lateral gazes, the PN increased in the abducting eye, but decreased in the adducting eye.[ncbi.nlm.nih.gov]

  • Brain Stem Infarction

    […] palsy, or convergence-retraction nystagmus.[emedicine.medscape.com] CN III palsy and pupillary abnormalities, including small pupils with decreased light reactivity (diencephalic), large/mid-position and fixed pupils (midbrain), and ectopic[emedicine.medscape.com] These patients can also demonstrate oculomotor abnormalities, most commonly of the vertical gaze, such as gaze palsy, skew deviation, convergence spasm resulting in pseudoabducens[emedicine.medscape.com]

    Missing: Interfamilial and Intrafamilial Clinical Heterogeneity
  • Nystagmus

    For other students, the null point may be when the eyes point up or down or to one side nystagmus will decrease as the eyes converge to look at a close object nystagmus will[svrc.vic.edu.au] Nystagmus may decrease when the eyes converge to read.[lowvision.org] Low vision specialists can add prism to induce convergence artificially and thus reduce the nystagmus in some patients.[lowvision.org]

    Missing: Interfamilial and Intrafamilial Clinical Heterogeneity
  • Communicating Hydrocephalus

    The ocular motility disorder consisted of severe vertical gaze palsy and convergence retraction nystagmus.[ncbi.nlm.nih.gov] On the other hand, striatal uptake did not decrease in (18)F-dihydroxyphenylalanine positron emission tomography, and anti-Parkinsonian drugs were not effective. 99mTc-ethyl[ncbi.nlm.nih.gov]

    Missing: Interfamilial and Intrafamilial Clinical Heterogeneity
  • Hereditary Nystagmus

    Nystagmus may decrease when the eyes converge to read.[lowvision.org] […] intensity decreases when converging to view near objects in around 44% of individuals with IN. 8,12 However, there is no significant improvement in near VA at this time,[dovepress.com] It is typically a horizontal jerk nystagmus and it may be associated with abnormal head movement and decreases in intensity with convergence.[medical-dictionary.thefreedictionary.com]

    Missing: Interfamilial and Intrafamilial Clinical Heterogeneity
  • Limb-Girdle Muscular Dystrophy

    ; Intrafamilial may be homogeneous or heterogeneous Gypsies with C283Y mutation Early Duchenne-like course but longer survival (50%) Becker phenotype (13%) Overall: More severe[neuromuscular.wustl.edu] […] features Severity Some with Duchenne-like course Others intermediate between Duchenne & Becker phenotype Mild Becker phenotype in occasional family Variable: Interfamilial[neuromuscular.wustl.edu] Skin, Spinal cord & Olfactory bulb Weakly: Cerebrum & Aorta Sarcoglycan binding: Moderately to β-sarcoglycan Homologous sarcoglycan: δ-sarcoglycan See: Sarcoglycan complex Clinical[neuromuscular.wustl.edu]

    Missing: Nystagmus Decreases on Convergence
  • Pseudoxanthoma Elasticum

    The definitive diagnosis of PXE is often hampered by extensive intrafamilial and interfamilial clinical heterogeneity ( 2, 5 ).[doi.org] The definitive diagnosis of PXE is often hampered by extensive intrafamilial and interfamilial clinical heterogeneity ( 2 , 5 ).[pnas.org]

    Missing: Nystagmus Decreases on Convergence
  • Vertebral Artery Thrombosis

    […] palsy, or convergence-retraction nystagmus.[emedicine.medscape.com] CN III palsy and pupillary abnormalities, including small pupils with decreased light reactivity (diencephalic), large/mid-position and fixed pupils (midbrain), and ectopic[emedicine.medscape.com] These patients can also demonstrate oculomotor abnormalities, most commonly of the vertical gaze, such as gaze palsy, skew deviation, convergence spasm resulting in pseudoabducens[emedicine.medscape.com]

    Missing: Interfamilial and Intrafamilial Clinical Heterogeneity
  • Vision Disorder

    These showed progressive decreases in nystagmus, improved control of the strabismic deviation, improved visual acuity, diminished diplopia, and markedly increased convergence[visiontherapystories.org] The therapy focused on improving ocular motility, fixation and alignment, as well as convergence ability and overall binocularity.[visiontherapystories.org]

    Missing: Interfamilial and Intrafamilial Clinical Heterogeneity
  • Infratentorial Tumor

    ., the Parinaud syndrome: decreased upward gaze, near-light dissociation of the pupillary response, convergence nystagmus) are classically noted ( 22 ).[radiologykey.com]

    Missing: Interfamilial and Intrafamilial Clinical Heterogeneity

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