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10 Possible Causes for Interictal Downbeat Nystagmus, Neurologic Signs Last Hours to Days

  • Familial Hemiplegic Migraine Type 2

    According to Baloh and others (1997), EA2 is characterized by a progressive ataxia with interictal rebound nystagmus evoked by gaze, as well as downbeating nystagmus.[dizziness-and-balance.com]

  • Spinocerebellar Ataxia Type 6

    Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com] About a year later, she noticed mild interictal imbalance.[jnnp.bmj.com]

    Missing: Neurologic Signs Last Hours to Days
  • Episodic Ataxia

    According to Baloh and others (1997), EA2 is characterized by a progressive ataxia with interictal rebound nystagmus evoked by gaze, as well as downbeating nystagmus.[dizziness-and-balance.com] Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com] About a year later, she noticed mild interictal imbalance.[jnnp.bmj.com]

    Missing: Neurologic Signs Last Hours to Days
  • Spastic Ataxia with Congenital Miosis

    Interictal examination showed spontaneous downbeat and gaze-evoked nystagmus and mild dysarthria and truncal ataxia.[findzebra.com] , episodic; Vertigo; Myotonia; Dysarthria; Migraine headache; Weakness; Paresthesias; Interictal downbeat nystagmus ; Interictal vestibular dysfunction; Interictal dystonia[findzebra.com] ; Gaze-evoked nystagmus ; Interictal downbeat nystagmus ; Ocular abnormalities often persist between attacks NEUROLOGIC: [Central nervous system]; Ataxia, episodic; Unsteadiness[findzebra.com]

    Missing: Neurologic Signs Last Hours to Days
  • Spinocerebellar Ataxia Type 4

    Initial examination disclosed a central type of positional nystagmus (conjugate downbeat nystagmus that did not fatigue with repeated positioning).[jnnp.bmj.com] About a year later, she noticed mild interictal imbalance.[jnnp.bmj.com]

    Missing: Neurologic Signs Last Hours to Days
  • Benign Paroxysmal Tonic Upgaze of Childhood with Ataxia

    Most patients also show various interictal nystagmus, such as gaze-evoked nystagmus (GEN), rebound nystagmus, or primary position downbeat nystagmus.[e-jmd.org]

    Missing: Neurologic Signs Last Hours to Days
  • Generalized Epilepsy - Paroxysmal Dyskinesia Syndrome

    Most patients also show various interictal nystagmus, such as gaze-evoked nystagmus (GEN), rebound nystagmus, or primary position downbeat nystagmus.[e-jmd.org]

    Missing: Neurologic Signs Last Hours to Days
  • Familial Episodic Pain Syndrome Type 1

    Most patients also show various interictal nystagmus, such as gaze-evoked nystagmus (GEN), rebound nystagmus, or primary position downbeat nystagmus.[e-jmd.org]

    Missing: Neurologic Signs Last Hours to Days
  • Infantile Periodic Alternating Nystagmus

    1 2-15 Seconds, minutes None Myokymia and jerky movements of face and limbs EA 2 2-20 Hours, days Downbeat nystagmus, migraine, vertigo, nausea, vomiting, weakness, dysarthria[hkjpaed.org] Table 2 Major types of autosomal dominant episodic ataxias (EA) Age of onset (years) Duration of attack Additional manifestations during attack Interictal manifestations EA[hkjpaed.org] Ataxia, nystagmus EA 3 1-42 1 minute to 6 hours Myokymia, migraine, tinnitus, vertigo, dysarthria None EA 4 23-60 Brief Vertigo, diplopia, interictal nystagmus and abnormal[hkjpaed.org]

    Missing: Neurologic Signs Last Hours to Days
  • Azathioprine

    In the Ellison 1989 trial, relapse was a worsening of neurological symptoms and signs lasting more than 24 hours and confirmed by the monitoring neurologist.[dx.doi.org] In the other trials, relapse was an exacerbation of at least five days duration with objective worsening of EDSS by 0.5 points ( Goodkin 1991 ) or 1 point ( British & Dutch[dx.doi.org]

    Missing: Interictal Downbeat Nystagmus

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