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1,625 Possible Causes for Interleukin-2, of, production, upregulation

  • Urinary Tract Infection

    (TLR2), which produces interleukin-10 (IL-10) and myeloid differentiation factor 88 (MyD88).[ncbi.nlm.nih.gov] products more than twice daily.[doi.org] We report here that UPEC upregulates the expression of ethanolamine utilization genes during uncomplicated UTIs in humans.[ncbi.nlm.nih.gov] I have had times of recurrent UTIs in my life and was so glad when I found this product.[azoproducts.com]

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  • Influenza

    In the 1997 outbreaks, elevated blood levels of interleukin-6, TNF-α, interferon-γ, and soluble interleukin-2 receptor were observed in individual patients, 42 and in the[doi.org] […] recent developments of interest include the use of immunopotentiators, development of DNA vaccines, use of reverse genetics, and the feasibility of mammalian cell-based production[ncbi.nlm.nih.gov] No significant upregulation was observed in either group of guinea pigs for TNFα, TBK1, IRF5, or IFNγ ( Figure 5 ).[dx.doi.org] Age-related decline in interleukin 2 production in response to influenza vaccine. J Am Geriatr Soc 1990;38:652--8. Govaert TM, Thijs CT, Masurel N, et al.[cdc.gov]

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  • Sunburn

    Together the data may have broad implications for the immunotherapeutic properties of vitamin D in skin homeostasis, and implicate arginase-1 upregulation as a previously[ncbi.nlm.nih.gov] The expression of several genes [interleukin-1β (IL-1β), IL-6, and cyclooxygenase-2 (COX-2)], previously shown to contribute to pain hypersensitivity, was significantly increased[doi.org] Summary Exposure to ultraviolet B radiation in sunlight provides the mechanism for more than 90% of the vitamin D production in most individuals.[doi.org] UVR activates release of membrane fatty acids and upregulates their metabolism by cyclooxygenases (COX) and lipoxygenases (LOX) to different eicosanoids.[ncbi.nlm.nih.gov]

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  • Otitis Media

    Abnormalities of this gene expression, especially upregulation of MUC5B in the ear, may have a predominant role in OME.[emedicine.medscape.com] MAIN OUTCOME MEASURE(S): Serum levels of C-reactive protein, ANCA titer, soluble interleukin-2 receptor levels, and hearing outcome.[ncbi.nlm.nih.gov] Alteration of distortion product otoacoustic emission input/output functions in subjects with a previous history of middle ear dysfunction .[doi.org] […] virulence mechanisms to colonize and survive in its host, including adherence and invasion of host cells, formation of polymicrobial biofilms with other bacterial pathogens, and production[ncbi.nlm.nih.gov]

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  • Infectious Mononucleosis

    The genes also grouped into 2 major groups; one that contained most of the mitochondrial function genes that were upregulated in cases and the other contained cell cycle checkpoints[dx.doi.org] The most specific serologic marker is high levels of soluble interleukin 2 receptor. Low natural killer cell number and activity is also a sensitive marker for HLH.[emedicine.com] The ultimate products of viral replication are virions.[doi.org] Binding of gp350 to CD21 activates several pathways, in particular NF-κB, which results in interleukin-6 (IL-6) upregulation ( 6 , 45 ).[dx.doi.org]

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  • Interleukin-2

    Moreover, the vaccine induced survivin- and MUC1-specific immune responses in splenocytes and induced the immune promoting factor CCL-19 and GM-CSF upregulated, while metastatic-associated[ncbi.nlm.nih.gov] Effects of interleukin-2 and interleukin-2-activated cells on in vitro myelopoiesis.[doi.org] Conclusion: We found that in SLE patients lymphocyte production of IL-2 did not decrease when compared with that of normal subjects.[ncbi.nlm.nih.gov] Also, IL-2 and IL-12 reciprocally upregulated each other's receptors, IL-2Rα and IL-12Rβ1/β2, on NK cells and their subsets in MM and HCs.[ncbi.nlm.nih.gov]

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  • Malignant Neoplasm

    The interleukin-2 receptor: a target for monoclonal antibody treatment of human T-cell lymphotrophic virus I-induced adult T-cell leukemia .[doi.org] […] customer service for these products.[amazon.com] Received: 28 October 2014 / Revised: 5 February 2015 / Accepted: 11 February 2015 / Published: 27 February 2015 Background: Intestinal exposure to gliadin leads to zonulin upregulation[dx.doi.org] HMGA1b protein interferes with estrogen-induced upregulation of BRCA1 .[doi.org]

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  • Daclizumab

    Abstract Although previous studies have described CD25 expression and production of interleukin-2 (IL-2) by mature dendritic cells (mDCs), it remains unclear how these molecules[ncbi.nlm.nih.gov] Entry D03639 Drug Name Daclizumab (USAN/INN); Zenapax (TN); Zinbryta (TN) Product ZINBRYTA (Abbvie) Formula C6394H9888N1696O2012S44 Exact mass 144031.1268 Mol weight 144119.9425[kegg.jp] Daclizumab exerts its effects via multiple mechanisms, including reduction of IL-2-mediated lymphocyte activation and upregulation of CD56-bright natural killer cells.[ncbi.nlm.nih.gov] A phase I trial of humanized anti‐interleukin2 receptor antibody in renal transplantation.[ndt.oxfordjournals.org]

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  • Tuberculosis

    Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway . J.[nature.com] 2 compared with placebo.[doi.org] […] genotyping assay to identify the Mycobacterium tuberculosis complex (MTC) species most prevalent in human tuberculosis (TB), based on the thermal denaturation profiles of PCR products[ncbi.nlm.nih.gov] Role of narK2X and narGHJI in hypoxic upregulation of nitrate reduction by Mycobacterium tuberculosis.[ncbi.nlm.nih.gov]

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  • X-Linked Severe Combined Immunodeficiency

    Abstract X-linked severe combined immunodeficiency disease (SCID) results from mutations of IL2RG, the gene encoding the interleukin-2 receptor gamma chain, also known as[ncbi.nlm.nih.gov] […] highlight variables that were found to be critical for transfection-based large-scale SIN gRV production.[ncbi.nlm.nih.gov] JAK3 is upregulated as the T cell is activated; downstream signaling by JAK3 triggers 3 additional signaling pathways, including the signal transducers and activators of transcription[emedicine.medscape.com] -2/chemistry Receptors, Interleukin-2/genetics* Receptors, Interleukin-2/therapeutic use Retroviridae/genetics Severe Combined Immunodeficiency/genetics Severe Combined Immunodeficiency[ncbi.nlm.nih.gov]

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