Intermediate Causes & Reasons

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Possible Causes

Toxoplasmosis

PCR was useful in the case of intermediate avidity. [ncbi.nlm.nih.gov]

Intermediate hosts in nature (including birds and rodents) become infected after ingesting soil, water or plant material contaminated with oocysts. [cdc.gov]

IgG avidity was low in 9 women suggesting an acute infection; 3 women presented an intermediate avidity. [ncbi.nlm.nih.gov]

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Uveitis

Keywords: Intermediate uveitis, pars planitis How to cite this article: Babu B M, Rathinam S R. Intermediate uveitis. [doi.org]

Intermediate uveitis Anterior vitreous cells in Intermediate uveitis Specialty Ophthalmology Intermediate uveitis is a form of uveitis localized to the vitreous and peripheral [en.wikipedia.org]

INTERMEDIATE UVEITIS • Intermediate uveitis (IU) is described as inflammation in the anterior vitreous, pars plana and the peripheral retina • The diagnostic term pars planitis [slideshare.net]

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Tumor Lysis Syndrome

The median S-UA on day 5 after chemotherapy was 3.3 mg/dl (range 1.1-5.8 mg/dl) (p CONCLUSION: Febuxostat is promising for the management of TLS of an intermediate-risk patient [ncbi.nlm.nih.gov]

RESULTS: A total of 346 patients (82.1% intermediate TLS risk; 82.7% assigned to standard dose) were randomized. [ncbi.nlm.nih.gov]

GCT is classified as intermediate risk for TLS, and the patients who have other TLS risks factors are classified to be at high risk for TLS. [ci.nii.ac.jp]

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Anterior Uveitis

Intermediate uveitis is a form of uveitis localized to the vitreous and peripheral retina. [en.wikipedia.org]

Abstract Anterior uveitis is far more common than intermediate, posterior or panuveitis. About 50% of patients with acute anterior uveitis are HLA B27 . [ncbi.nlm.nih.gov]

[…] corticosteroids is reserved for patients, especially with associated chronic inflammatory bowel disease or psoriatic arthritis presenting with bilateral, chronic, anterior, and/or intermediate [ncbi.nlm.nih.gov]

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Maple Syrup Urine Disease

Three children were diagnosed with the intermediate form of maple syrup urine disease during routine evaluation of mental retardation. [ncbi.nlm.nih.gov]

We describe two patients with an intermediate form of MSUD who presented later in childhood. [ncbi.nlm.nih.gov]

An 8-year-old boy with the intermediate variant of maple syrup urine disease is reported. [ncbi.nlm.nih.gov]

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Macular Degeneration

Purpose: To investigate the relationship between perfusion of the choriocapillaris (CC) and macular function in eyes with intermediate age-related macular degeneration. [ncbi.nlm.nih.gov]

LLQ is a useful patient-centered functional measure of visual impairment in early and intermediate AMD. [ncbi.nlm.nih.gov]

To determine whether angiography with swept-source (SS) optical coherence tomography (OCT) identifies subclinical type 1 neovascularization in asymptomatic eyes with intermediate [ncbi.nlm.nih.gov]

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Choledocholithiasis

METHODS: In 2014, 109 patients with intermediate risk of choledocholithiasis underwent endoscopic ultrasound. Their medical records were retrospectively reviewed. [ncbi.nlm.nih.gov]

Conclusion: Only strong clinical predictors of choledocholithiasis showed predictability for patients with intermediate risk of choledocholithiasis. 2016 S. [karger.com]

Asses role of EUS in patients with intermediate and high risk of CBD stone before ERCP. Design. [actagastro.org]

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Pulmonary Embolism

In intermediate-risk PE, clinical success for CDT and usCDT was 95.0% (95% CI, 88.5%-99.2%) and 97.5% (95% CI, 95.0%-99.4%), respectively. [ncbi.nlm.nih.gov]

A total of 5,622 patients with low/intermediate or unlikely PTP were assessed using the VIDAS D-dimer. [ncbi.nlm.nih.gov]

Differently, the prevalence of T- wave inversion was similar in high and intermediate-risk patients. [ncbi.nlm.nih.gov]

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Pituicytoma

Ultrastructurally, the lesion was composed of elongated cells containing in the Golgi area aggregates of intermediate filaments in a concentric pathway (fibrous body), and [ncbi.nlm.nih.gov]

These features intermediate between a pituicytoma and a pituitary adenoma suggest that pituicytomas may also arise from the specialized stromal folliculo-stellate cells of [doi.org]

Electron microscopy identified intermediate filaments, numerous broad cell junctions, no secretory granules, and two cellular populations with either an electron-dense or [ncbi.nlm.nih.gov]

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Refractory Anemia with Excess Blasts in Transformation

Most people with RAEB will fall into the intermediate-1, intermediate-2 or high risk categories. [leukaemia.org.au]

1 0.5-1.0 3.5 years 3.3 years Intermediate-2 1.5-2.0 1.2 years 1.1 years High 2.5 0.4 years 0.2 years Treatment based on risk group assigned and ability to tolerate therapy [surgpathcriteria.stanford.edu]

1, intermediate- 2, and high-risk International Prognostic Scoring System groups. [medical-dictionary.thefreedictionary.com]

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Myelodysplasia

After intensive treatment, the median survival was 2.6 years for the intermediate 1 risk group (n 33), 3.4 years for the intermediate 2 risk group (n 27) and 0.9 years for [ncbi.nlm.nih.gov]

For low- and intermediate-1-risk MDS, delayed BMT is associated with maximal life expectancy, whereas immediate transplantation for intermediate-2- and high-risk disease is [ncbi.nlm.nih.gov]

Among patients with intermediate-risk cytogenetics, median overall survival with azacitidine was 16.4 months, and with CCR was 8.9 months (hazard ratio 0.73 [95%CI 0.48, 1.10 [ncbi.nlm.nih.gov]

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Alexander Disease

[…] mice in which the corresponding intermediate filament gene has been inactivated. [ncbi.nlm.nih.gov]

We describe three patients with unique characteristics, and whose mutations have implications for AxD diagnosis and studies of intermediate filaments. [ncbi.nlm.nih.gov]

AxD is caused by mutations in GFAP, the main astrocyte intermediate filament protein. [ncbi.nlm.nih.gov]

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Idiopathic Anterior Uveitis

[…] block and iris bombé iris nodules: Koeppe (small, near pupil), Bussaca (large, far from pupil) Anterior vitreous cells may be seen in iridocyclitis but often will indicate intermediate [college-optometrists.org]

It is classified into three categories: 1) Anterior (inflammation of iris and ciliary body); 2) Intermediate (ciliary body, pars plana); and, 3) Posterior (choroid) uveitis [vin.com]

Findings of intermediate and posterior uveitis are most easily seen after dilating the pupil. [merckmanuals.com]

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Diffuse Lymphoma

The International prognostic index (IPI) is the standard method of assessing prognosis at presentation. 0 – 1 Low 2 Low-intermediate 3 High-intermediate 4 High Age (years) [hmds.info]

[…] risk; 3, high-intermediate risk; and 4 to 5, high risk. [jhoonline.biomedcentral.com]

In patients with high-intermediate–risk/high-risk DLBCL, a phase II study of brentuximab vedotin (Adcetris) with R-CHOP is yielding positive results, especially in patients [ascopost.com]

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Myelofibrosis

KEYWORDS: IPSS; MF; intermediate-1 risk; myelofibrosis; ruxolitinib [ncbi.nlm.nih.gov]

The IPSS and DIPSS-plus were the best models to discriminate between the intermediate-1 and intermediate-2 risk categories, which is a critical cut-off point for patient selection [ncbi.nlm.nih.gov]

2, 21% intermediate-1 and 3% low. [ncbi.nlm.nih.gov]

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Panuveitis

CONCLUSIONS: This systematic review highlights the heterogeneity of outcome measures used in recent clinical trials for intermediate, posterior, and panuveitis. [ncbi.nlm.nih.gov]

Results: One hundred and fifty-nine intermediate uveitis, posterior uveitis, and panuveitis patients (237 eyes) were identified. [dovepress.com]

The FDA has approved AbbVie ’s Humira (adalimumab) for the treatment of non-infectious intermediate, posterior and panuveitis. [centerwatch.com]

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Aortic Valve Stenosis

In the present study, we have asked whether levels of the circulating intermediate monocyte subset are increased in AS. [ncbi.nlm.nih.gov]

In Northwestern Europe, the TAVR technology is also increasingly used to treat patients with an intermediate risk profile. [ncbi.nlm.nih.gov]

BACKGROUND: Patients at intermediate risk (IR) according to The Society of Thoracic Surgeons risk score are today frequently oriented toward the transfemoral aortic valve [ncbi.nlm.nih.gov]

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Pilomyxoid Astrocytoma

Some cases, as in this present one, have simultaneous histological features of pilocytic and pilomyxoid astrocytomas, constituting a group called intermediate pilomyxoid astrocytoma [ncbi.nlm.nih.gov]

Spectrum of pilomyxoid astrocytomas: intermediate pilomyxoid tumors. Am J Surg Pathol. 2010;34(12):1783-91. [ Links ] 10. [scielo.br]

[…] enhancement Occasional CSF dissemination Gross images Images hosted on other servers : Coronal sections through hypothalamus Microscopic (histologic) description Monomorphous intermediate [pathologyoutlines.com]

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Congenital Bile Acid Synthesis Defect Type 2

The resultant intermediates cannot be secreted into the bile and thus appear in blood and urine. [symptoma.com]

[…] stimulates bile flow and facilitates fat soluble vitamin absorption and suppresses atypical bile acid synthesis thereby reducing the production of toxic bile acid metabolic intermediates [rarediseases.info.nih.gov]

The abnormal intermediates accumulating in CBAS2 patients have been postulated to exert hepatotoxic effects. [symptoma.com]

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Acute Coronary Syndrome

Intermediate: above 3% and up to 6%. High: above 6%. [patient.info]

Risk Rise and/or fall in troponin level consistent with myocardial infarction Dynamic episode of ST segment and/or T wave changes with or without symptoms GRACE score 140 Intermediate [litfl.com]

Noninvasive testing and imaging for diagnosis in patients at low to intermediate risk for acute coronary syndrome. . Accessed Feb. 20, 2019. Cardiac medications. [mayoclinic.org]

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Ganglioneuroblastoma

Ganglioneuroblastoma is an intermediate tumor that arises from nerve tissues. [nlm.nih.gov]

It is contained within the neuroblastic tumors group, which includes: Ganglioneuroma (benign) Ganglioneuroblastoma (intermediate). [en.wikipedia.org]

Grading / Staging Clinical staging classifies patients into low, intermediate and high risk groups based on: Patient age (most important) International Neuroblastoma Pathology [surgpathcriteria.stanford.edu]

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Distal Spinal Muscular Atrophy Type 5

Dominant Intermediate CMT (DI-CMT) is so named owing to their “intermediate” conduction velocities and thus an uncertainty regarding whether the neuropathy is primarily axonal [rarediseases.org]

Their nerve conduction studies tend to be in the intermediate range of between 35 and 45 m/s. [cmtausa.org]

A dominant-intermediate classification (DI-CMT) may also be encountered. [now.aapmr.org]

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Rhabdomyosarcoma

[…] histologic, immunohistochemical, and molecular findings documented for the first time a chronological progression from an invasive MM to a pleomorphic rhabdomyosarcoma through an intermediate [ncbi.nlm.nih.gov]

Patients at intermediate risk of treatment failure also require three-drug chemotherapy. [ncbi.nlm.nih.gov]

The overall survival rate for this group is more than 90%. [19] Patients with intermediate risk and an intermediate prognosis include those with embryonal rhabdomyosarcoma [emedicine.com]

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Epidermolysis Bullosa Simplex

We therefore suggest that an imbalance of cytoplasmic K14 monomers and K14 incorporated into the intermediate filament (IF) network leads to elevated stress signalling, potentially [ncbi.nlm.nih.gov]

Basal keratinocytes in skin and in culture completely lacked keratin 14 and intermediate filaments. [ncbi.nlm.nih.gov]

Ultrastructurally, hemidesmosomes were fairly normal, but the attachment of intermediate filaments with the hemidesmosomal plaques appeared to be impaired. [ncbi.nlm.nih.gov]

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Gynandroblastoma

Histological study revealed, the tumour was composed of mixed sex cord elements with predominantly intermediate differentiated Sertoli-Leydig cell component and a second adult [ncbi.nlm.nih.gov]

The testicular-type elements accounted for 20% of the tumor and resembled intermediate-grade SLCT. [ncbi.nlm.nih.gov]

Following surgical excision, the ovarian mass was diagnosed as gynandroblastoma, which consisted of 45% juvenile granulosa cell tumor and 55% intermediately differentiated [wwww.unboundmedicine.com]

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Diabetes Mellitus

Background: Intermediate hyperglycaemia (IH) is characterised by one or more measurements of elevated blood glucose concentrations, such as impaired fasting glucose (IFG), [cochrane.org]

Intermediate DEND (iDEND) syndrome is a rare mild form of DEND syndrome. [ncbi.nlm.nih.gov]

In addition, intermediate and long-acting insulins also contain ingredients that prolong their actions. [web.archive.org]

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Post-Polycythemia Vera Myelofibrosis

The purpose of this study is to assess the effectiveness of fedratinib in successive 28-day cycles to treat subjects with intermediate or high-risk primary myelofibrosis, [rush.edu]

Methods: Eligibility criteria include age of at least 18 years, platelets 50,000/µl, ECOG PS 0–2, and a diagnosis of high- or intermediate-risk 2 primary MF, post-PV MF, or [ascopubs.org]

HR (95% CI) using IPSS were 2.3 (1.4–3.7) for high vs intermediate-2, 4.3 (2.2–8.5) for high vs intermediate-1, 6.6 (2.9–15.3) for high vs low, 2.9 (1.3–6.7) for intermediate [nature.com]

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Sertoli Leydig Cell Tumor

Microscopically, the tumor was composed of intermediately differentiated Sertoli-Leydig cell tumor and well-differentiated mucinous adenocarcinoma. [ncbi.nlm.nih.gov]

We present the fourth case of an ovarian SLCT of intermediate differentiation with rhabdomyosarcoma and a review of the literature. [ncbi.nlm.nih.gov]

Here, we report a SLCT with intermediate differentiation in a 23-year-old woman investigated by light microscopy, immunohistochemistry for intermediate filaments, and sex [ncbi.nlm.nih.gov]

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Primary Mediastinal Large B-Cell Lymphoma

[…] patients (43%) an intermediate-high/high (2 to 3) International Prognostic Index (IPI) score. [ncbi.nlm.nih.gov]

[…] distinguishing between classical Hodgkin's lymphoma (cHL) and primary mediastinal B-cell lymphoma (PMBCL) to more narrowly define 'B-cell lymphoma, unclassifiable, with features intermediate [ncbi.nlm.nih.gov]

These studies provide further evidence that PMLBCL and nodular sclerosis CHL may represent related tumors on either ends of a continuum, whose interface includes an intermediate [ncbi.nlm.nih.gov]

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Echinococcosis

Natural intermediate hosts depend on genotype. [cdc.gov]

E. oligarthrus (up to 2.9 mm long) has a life cycle that involves wild felids as definitive hosts and rodents as intermediate hosts. [web.archive.org]

Humans are aberrant intermediate hosts, and become infected by ingesting eggs. [cdc.gov]

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