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14 Possible Causes for Intermittent Jaundice, Microcytic Anemia, Uric Acid Increased

  • Hereditary Spherocytosis

    Abstract Hereditary spherocytosis is an autosomal dominant congenital hemolytic anemia due to defect in RBC membrane protein that commonly presents with intermittent jaundice[] anemia of varying degree. [3] Uraninite is a radioactive, uranium-rich mineral and ore with a chemical composition that is largely UO2, but also contains UO3 and oxides of[] Dubin-Johnson syndrome is a chronic, benign, intermittent jaundice, mostly of conjugated hyperbilirubinemia.[]

  • Sickle Cell Disease

    Each individual with SCD is unique, but the most common features are: Anemia (may cause fatigue and decreased endurance), reticulocytosis, and jaundice Intermittent acute[] Some causes of microcytic anemia, most notably iron deficiency, are characterized by an increase in RDW.[] Consequences of hemolysis may include chronic anemia, jaundice, predisposition to aplastic crisis, cholelithiasis, and delayed growth and sexual maturation.[]

  • Refractory Megaloblastic Anemia

    […] degree of in effective erythropoiesis · Haptoglobins, Uric acid and alkaline phosphatase levels – Decreased. · Serum methylmalonate and homocystein levels - Vitamin B-12[] He has a fever and you note jaundice. You order an ultrasound of his abdomen and find multiple gallstones. Lab results: Hct .36 L/L; Hgb 120 g/L. PBS at right.[] Iron Deficiency Anemia (IDA) White cells Not remarkable Platelets Normal or slightly increased Red cells Hb and Hct decreased Microcytic, hypochromic anemia Reticulocytes[]

  • Congenital Liver Cirrhosis

    acid level elevated Maternal mortality, 1%; prematurity and fetal death, 5%-30% Beta blocker, methyldopa, magnesium sulfate; early delivery HELLP syndrome Beyond 22 wk and[] He had intermittent high grade fever with dry cough and respiratory distress for 4 days duration.[] Anemia is often multifactorial; contributing factors may include chronic GI bleeding (usually causing microcytic anemia), folate nutritional deficiency (causing macrocytic[]

  • Progressive Retinal Dystrophy due to Retinol Transport Defect

    […] serum uric acid levels. ( 27151312 ) Solak B....Solak Y. 2016 15 Relationship between acne vulgaris and attention-deficit/hyperactivity disorder symptoms in a clinical sample[] […] sinusitis Abnormality of the cerebral vasculature Thyroiditis Vitamin E deficiency Antinuclear antibody positivity Abnormality of the thyroid gland Prostatitis Macular atrophy Intermittent[] anemia; Hypodontia; Hypofibrinogenemia; Hypoglobulinemia and absent B cells; Hypogonadism (hypergonadotropic); Hypogonadotropic (hypogonadism); Hypokalemic periodic paralysis[]

  • Hexokinase Deficiency

    Uric Acid), and the patient presents Hyperuricemia.[] Intermittent jaundice and premature pigment gallstones are common. Splenomegaly is characteristic (palpable in 75% to 80% of cases).[] Since the production of ATP is impaired, Adenine accumulates and its conversion to Uric acid increases (recall that in the catabolism of purines adenine and Guanine become[]

  • Glucose-6-Phosphate Dehydrogenase Deficiency

    An acid urine pH favors production of poorly soluble uric acid over the more soluble urate, increasing the risk for precipitation of intratubular uric acid crystals.[] To determine whether you have an inherited G6PD deficiency When a child experienced persistent jaundice as a newborn for unknown reasons; when you have had one or more intermittent[] HbE is asymptomatic or is manifested as microcytic, minimally hemolytic anemia. The association between G6PD deficiency and HbE is little understood.[]

  • Pneumatosis Vaginalis

    LESCH-NYHAN SYNDROME: Deficiency of HGPRT (Hypoxanthine-Guanine Phospho-ribosyltransferase ------ Hyperuricemia, uric acid kidney stones Choreoathetosis Mental retardation[] He is receiving intermittent orogastric feeding of expressed human milk and supplemental parenteral nutrition.[] All of the following conditions are characterized by hypochromic, microcytic red cells EXCEPT a. iron deficiency anemia b. alpha thalassemia major c. beta thalassemia minor[]

  • Familial Pseudohyperkalemia

    Microalbuminuria Increased WBC count Increased C-reactive protein Increased fibrinogen Increased pro inflammatory cytokines Increased uric acid Type 2 DM Fatty Liver HTN and[] Patients with HC1 may present later in life with macrocytosis, anemia, reticulocytosis, intermittent jaundice, gallstones, a palpable spleen tip, stomatocytosis, or because[] Evidence of iron deficiency anemia may be present where erythrocytes are hypochromic and microcytic. Leukoerythroblastosis and poikilocytosis are not seen.[]

  • Beta-Ureidopropionase Deficiency

    Plasmodium falciparum (malaria parasite) Along with many other disease causing parasites -Juvenile gout -No salvage of purines, therefore causing an increase in uric acid[] Intellectual disability, seizures, and periodic loss of balance and coordination (intermittent ataxia).[] (AA) Atransferrinemia Scott syndrome Thiamine-responsive megaloblastic anemia (TRMA) Hypochromic microcytic anemia Plasminogen deficiency Rh-null hemolytic anemia (RHN) Bleeding[]

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