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18 Possible Causes for Intermittent Jaundice, Splenomegaly, Uric Acid Increased

  • Hereditary Spherocytosis

    Due to the membrane defect, there is increased fragility, hemolytic anemia, marked splenomegaly and hyperbilirubinemia.[ncbi.nlm.nih.gov] Dubin-Johnson syndrome is a chronic, benign, intermittent jaundice, mostly of conjugated hyperbilirubinemia.[ncbi.nlm.nih.gov] Fatigue is associated with intermittent jaundice.[explainmedicine.com]

  • Primary Biliary Cirrhosis

    […] of the caudate lobe hepatic surface irregularity due to regenerative nodules regional lymphadenopathy: tends to dominate in the gastrohepatic ligament and porta hepatis 4 splenomegaly[radiopaedia.org] Twenty four hour urine demonstrated a low renal fractional tubular reabsorption of phosphate, increased fractional excretion of uric acid and generalized aminoaciduria.[ncbi.nlm.nih.gov] Reddy AN, Grosberg SJ, Wapnick S: Intermittent cholestatic jaundice and nonmetastatic prostatic carcinoma. Arch Intern Med 1977;137:1616–1618.[clevelandclinicmeded.com]

  • Hepatorenal Syndrome

    […] to advanced liver disease including the accumulation of fluid in the abdomen (ascites), yellowing of the skin and the whites of the eyes (jaundice), an enlarged spleen (splenomegaly[rarediseases.org] Wui-Chiang Lee, Han-Chieh Lin, Ming-Chih Hou, Hsiao-Yi Lin, Fa-Yauh Lee, Sun-Sang Wang, Full-Young Chang and Shou-Dong Lee , Serum Uric Acid Levels in Patients With Cirrhosis[dx.doi.org] Severe circulatory dysfunction (mean arterial pressure usually is 70 mm Hg) and very low systemic vascular resistance. • Severe liver disease, with jaundice, coagulopathy,[scielo.mec.pt]

  • Hemolytic Anemia due to a Disorder of Glycolytic Enzymes

    Related phenotypes are splenomegaly and abnormality of metabolism/homeostasis OMIM : 58 Hexokinase deficiency is an autosomal recessive disorder characterized by early-onset[malacards.org] However, inosine, which is a naturally occurring substance, increases plasma uric acid levels ( 38 ).[nature.com] jaundice and episodes of red/ dark urine Venous thrombosis in unusual locations (e.g., hepatic, cerebral, abdominal veins) Vasoconstriction : headache, pulmonary hypertension[amboss.com]

  • Diabetic Enteropathy

    Look for signs of chronic liver disease (eg, jaundice, splenomegaly, prominent veins on the abdomen).[patient.info] […] risk of acute coronary ischaemia Autonomic dysfunction: Increased sympathetic nervous system activity Type 2 diabetes Uric acid levels 50% higher with neuropathy than without[neuromuscular.wustl.edu] Typical symptoms of biliary colic include intermittent right upper abdominal pain, jaundice, or pancreatitis.[journal.diabetes.org]

  • Congenital Liver Cirrhosis

    The affected female, who was also known to have had a splenomegaly, died at age 5 ( Fig. 5 ).[kjim.org] acid level elevated Maternal mortality, 1%; prematurity and fetal death, 5%-30% Beta blocker, methyldopa, magnesium sulfate; early delivery HELLP syndrome Beyond 22 wk and[clevelandclinicmeded.com] He had intermittent high grade fever with dry cough and respiratory distress for 4 days duration.[indianpediatrics.net]

  • Refractory Megaloblastic Anemia

    Examples include causesof splenomegaly, indications for splenectomy, differential diagnosis of normocytic anemia,macrocytic anemia, hypochromic anemia, thrombocytopenia, bone[books.google.de] […] degree of in effective erythropoiesis · Haptoglobins, Uric acid and alkaline phosphatase levels – Decreased. · Serum methylmalonate and homocystein levels - Vitamin B-12[sites.google.com] He has a fever and you note jaundice. You order an ultrasound of his abdomen and find multiple gallstones. Lab results: Hct .36 L/L; Hgb 120 g/L. PBS at right.[med-ed.virginia.edu]

  • Pericholangitis

    PH YS IC AL EX AM IN AT IO N Abnormal physical findings • Jaundice • Hepatomegaly • Splenomegaly • Ascites and edema • Spider angiomata • Leukonychia • Muscle wasting • Gynecomastia[es.scribd.com] acid stones Migratory arthritis Sacroiliitis and ankylosing spondylitis Erythema nodosum and uveitis Complications Toxic megacolon Adenocarcinoma of the colon (1-16%) Increased[learningradiology.com] Clinically, this condition usually manifests with chronic intermittent obstructive jaundice. Abdominal pain, pruritus, fatiguability and fever are variably present.[sonoworld.com]

  • Hexokinase Deficiency

    Jaundice, splenomegaly, pallor and constitutional symptoms such as lethargy and fatigue are main symptoms.[symptoma.com] Uric Acid), and the patient presents Hyperuricemia.[biochemistryquestions.wordpress.com] Intermittent jaundice and premature pigment gallstones are common. Splenomegaly is characteristic (palpable in 75% to 80% of cases).[web.archive.org]

  • Optic Nerve Edema-Splenomegaly Syndrome

    Who Is at Risk for Splenomegaly? What Causes an Enlarged Spleen? Common Symptoms Diagnosing Splenomegaly Treating Splenomegaly Who Is at Risk for Splenomegaly?[rosenfeldinjurylawyers.com] , Blood Thyroid Stimulating Hormone Increased, Blood Uric Acid Increased, Blood Urine, Blood Urine Present, Body Height Below Normal, Body Height Increased, Body Temperature[bonkersinstitute.org] Presents in teens with intermittent jaundice and hepatomegaly.[quizlet.com]

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