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29 Possible Causes for Intermittent Severe Hypoglycemia

  • Leucine-induced Hypoglycemia

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  • Wolfram Syndrome

    She now wears a continuous glucose monitor due to her profound hypoglycemic unawareness with severe hypoglycemia.[hoajonline.com] She performs intermittent self-catheterization every 4 hours due to bladder atony.[hoajonline.com]

  • Insulin-Resistance Syndrome Type B

    These autoantibodies may block insulin binding or stimulate the insulin receptor leading to intermittent hypoglycemia.[diabeteslibrary.org] Type B insulin resistance syndrome affects middle-aged women characterized by severe hyperinsulinemia, features of hyperandrogenism and autoimmune disorders.[diabeteslibrary.org]

  • Olivopontocerebellar Atrophy

    Hyperalaninemia Severe retardation, siezures, myoclonus, in childhood.[cmdg.org] Very low levels of beta-hexosaminidase in serum, Leukocytes, and cultured fibroblasts Neutral amminoaciduria (Hartnup disease) Pellagra type rash, and intermittent ataxia,[cmdg.org] Ketoacidosis, and increased alanine in urine, and serum Hyperammonemia I and II; Increased ammonia, Hypoglycemia Galactocerebrosidase Lipidosis (Krabbe Disease) Early oset[cmdg.org]

  • Hypoglycemic Encephalopathy

    In this case, the patient suffered from intermittent hypoglycemia for three years.[ijcasereportsandimages.com] Later on due to sustained unaware hypoglycemic state, he developed prolonged delirium followed by severe extra pyramidal symptoms in the form of akinesia, rigidity (axial[ijcasereportsandimages.com]

  • Laron Syndrome with Immunodeficiency

    Intermittent hyperventilation Narrow palm Temperature instability Multiple pterygia Abnormality of the philtrum Excessive salivation Hyperinsulinemic hypoglycemia Misalignment[mendelian.co] […] phalanx of finger Pulmonary hypoplasia Abnormal cardiac septum morphology Blepharophimosis Abnormality of the pinna Hypospadias Bicuspid aortic valve Intellectual disability, severe[mendelian.co]

  • Hyperalaninemia

    Abstract The cause of severe intermittent lactic acidosis was investigated in a female infant with profound psychomotor retardation.[pediatrics.aappublications.org] Hyperalaninemia Severe retardation, siezures, myoclonus, in childhood Ketoacidosis, and increased alanine in urine, and serum Hyperammonemia I and II; Increased ammonia Hypoglycemia[cmdg.org] Hypoglycemia, hyperpyruvic acidemia, and hyperalaninemia were identified in the newborn period.[pediatrics.aappublications.org]

  • Autoimmune Adrenal Insufficiency

    SIGNS AND SYMPTOMS In a patient with T1DM, Addison’s disease may present as intermittent, severe hypoglycemia and intermittent, severe fatigue.[hopkinsguides.com]

  • Dumping Syndrome

    Several glucose tolerance tests were highly pathological with marked hyperglycemia immediately after a gastrostomy meal followed by hypoglycemia two hours later.[ncbi.nlm.nih.gov] Both infants were fed postoperatively via a gastrostomy and showed the typical clinical picture of dumping with failure to thrive, intermittent diarrhea, lethargy and pallor[ncbi.nlm.nih.gov]

  • Barth Syndrome

    Ninety percent of patients show mild to severe intermittent or persistent neutropenia with a risk of septicemia, severe bacterial sepsis, mouth ulcers and painful gums.[orpha.net] ; persistent, intermittent, or perfectly cyclic), compensatory monocytosis, recurrent bacterial infection, hypoglycemia, lactic acidosis, growth, and pubertal delay, feeding[frontiersin.org] There is a tendency to hypoglycemia during the neonatal period.[orpha.net]

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