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312 Possible Causes for Intractable Severe Seizures

  • Cerebral Thrombosis

    […] prophylaxis is indicated if a patient with CVT has a seizure in patients with neurological deterioration due to severe mass effect or intracranial hemorrhage causing intractable[] […] avoid estrogen-based contraception (can use progestogen only pill or intra-uterine devices such as Mirena) e.g. treat para-meningeal infection treat complications secondary seizure[]

  • Early Infantile Epileptic Encephalopathy

    It is an extremely debilitating progressive neurological disorder, involving intractable seizures and severe developmental delays.[] It is an extremely debilitating progressive neurological disorder, involving intractable seizures and severe intellectual disabilities.[] When EIEE is suspected, rapid and comprehensive genetic testing is critical to starting the child on a therapy that can prevent intractable seizures and severe cognitive dysfunction[]

  • Ohtahara Syndrome

    It is a debilitating and early progressive neurological disorder, resulting in intractable seizures and severe mental retardation.[] OHTAHARA SYNDROME Overview Ohtahara syndrome (also known as early infantile epileptic encephalopathy, EIEE) is a syndrome characterized by frequent intractable seizures and[] It is an extremely debilitating progressive neurological disorder, involving intractable seizures and severe intellectual disabilities.[]

  • Dehydration

    Severe hyponatremia may lead to intractable seizures, whereas rapid correction of chronic hyponatremia ( 2 mEq/L/h) has been associated with central pontine myelinolysis.[]

  • Epilepsy

    These epilepsies are also among the most severe with dire consequences including intractable seizures and severe cognitive dysfunction.[] […] is often profound; medical intractability; and severe consequences for a normal development.[] These epilepsies share several important characteristics: diverse causes; severe and frequent seizures; diffusely abnormal background activity on electroencephalograms that[]

  • Temporal Lobe Epilepsy

    In some patients initial response to medications may moderate over years leading to progressive worsening of seizure severity and frequency.[] For patients with medial TLE whose seizures remain uncontrolled after trials of several types of anticonvulsants (that is, the epilepsy is intractable), surgical excision[] Intractable epilepsy may lead to memory and psychological abnormalities.[]

  • West Syndrome

    Recent study has shown that mutations in the alpha-II-spectrin (SPTAN1) gene cause early onset intractable seizures, severe developmental delay, diffuse hypomyelination, and[] It is characterized by intractable seizures occurring almost daily, severe psychomotor retardation, poor prognosis and EEG abnormalities, known as hypsarrhythmia.[] Abstract The West syndrome and the Lennox-Gas-taut syndrome are characterized by their onset in infancy and early childhood, intractable seizures occurring almost daily, severe[]

  • Generalized Epilepsy with Febrile Seizures Plus

    They include severe myoclonic epilepsy in infancy (SMEI) and intractable childhood epilepsy with GTC (ICEGTC).[] Severe myoclonic epilepsy of infancy (SMEI) is an intractable epilepsy of early childhood of unknown etiology.[] Several missense SCN1A mutations have been identified in probands affected by the syndrome of intractable childhood epilepsy with generalized tonic-clonic seizures (ICEGTC[]

  • Rasmussen Syndrome

    , early onset disease and intractable seizures.[] Rasmussen Encephalitis, a chronic progressive encephalitis results in severe, intractable epilepsy.[] It is characterized by chronic, active encephalitis (inflammation of the brain) and by epileptic seizures of varying degrees of severity.[]

  • Uncinate Seizure

    […] to experience seizures even after surgery.[] New research from the University of Liverpool, published in the journal Brain, has highlighted the potential reasons why many patients with severe epilepsy still continue[] Medically intractable temporal lobe epilepsy (TLE) remains the most frequent neurosurgically treated epilepsy disorder.[]

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