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2,896 Possible Causes for Intrahepatic Cholestasis, Pancytopenia, Polyclonal Hyperglobulinemia

  • Chronic Active Hepatitis

    Abstract A 28-year-old man was admitted to our department with intermittent fever, hepatosplenomegaly and pancytopenia.[ncbi.nlm.nih.gov] hyperglobulinemia.[hepatitiscentral.com] Additionally, some authorities require the presence of immunologic features, particularly high titers (usually more than 1:40) of certain non organic specific autoantibodies and polyclonal[hepatitiscentral.com]

  • Chronic Active Hepatitis B

    hyperglobulinemia.[hepatitiscentral.com] A 28-year-old man was admitted to our department with intermittent fever, hepatosplenomegaly and pancytopenia.[ncbi.nlm.nih.gov] Compression of bile canaliculi may result in intrahepatic cholestasis.[hepatitisbannual.org]

  • Hepatosplenic Lymphoma

    Bone marrow infiltration results in pancytopenia .[wikidoc.org] Patients presented with fatigue, hepatosplenomegaly, and pancytopenia.[pediatrics.aappublications.org] The doctor and I both thought it was a bowel obstruction, but the cat scan showed an enormous spleen and bloodwork should pancytopenia (low blood counts on everything).[csn.cancer.org]

    Missing: Polyclonal Hyperglobulinemia
  • Cholestasis

    We report a case of severe CMV hepatitis in an immunocompetent patient presenting with cholestasis, portal hypertension-related ascites and pancytopenia.[ncbi.nlm.nih.gov] Intrahepatic cholestasis of pregnancy is a liver disorder that occurs in pregnant women.[ghr.nlm.nih.gov] We report a case with serial intrauterine transfusions complicated by pancytopenia and cholestasis in the neonatal period.[ncbi.nlm.nih.gov]

    Missing: Polyclonal Hyperglobulinemia
  • Hepatic Sarcoidosis

    Laboratory studies detected: cholestasis, pancytopenia and elevaton of angiotensin-converting enzyme.[ncbi.nlm.nih.gov] In 12 of these 47 patients, portal hypertension appeared to be a consequence of cirrhosis due to longstanding intrahepatic cholestasis; in white patients, this condition was[ncbi.nlm.nih.gov] cholestasis vs. extrahepatic cholestasis.[imrespdx.com]

    Missing: Polyclonal Hyperglobulinemia
  • Non-Hodgkin Lymphoma

    Leukemia commonly occurring after alkylating agent treatment; manifestations include pancytopenia, megaloblastic bone marrow, and nucleated red cells in peripheral marrow;[icd9data.com] […] suspected NHL should include the following: CBC count: May be normal in early-stage disease; in more advanced stages, may demonstrate anemia, thrombocytopenia/leukopenia/pancytopenia[emedicine.com]

    Missing: Polyclonal Hyperglobulinemia
  • Drug Hypersensitivity

    Five of the 6 patients who died had pancytopenia shortly before death (83%) ( Table 1 ). Acute renal failure developed in 5 of 60 patients (8%).[doi.org] […] hepatitis, pneumonitis, renal failure, hemophagocytic syndrome, encephalitis Not described Lung involvement—10 (67%) Liver involvement—7 (47%) Renal involvement—5 (33%) Pancytopenia[ncbi.nlm.nih.gov] Blackford, The Case of the Previously Shaky, Unimmunized, Itchy Infant With Rash and Pancytopenia, Clinical Pediatrics, 55, 14, (1366), (2016). Heather M.[doi.org]

    Missing: Polyclonal Hyperglobulinemia
  • Sarcoidosis

    The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites.[ncbi.nlm.nih.gov] Hepatosplenomegaly, intrahepatic cholestasis, and portal hypertension are rare. w7 Renal (5%) —Extrarenal production of calcitriol by macrophages can result in renal calculi[doi.org] In isolated cases, hypersplenism causes various grades of anaemia leuko-penia, thrombocytopenia, to severe conditions including pancytopenia.[pneumologia.eu]

    Missing: Polyclonal Hyperglobulinemia
  • Multicentric Castleman's Disease

    Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present.[ncbi.nlm.nih.gov] hyperglobulinemia, elevated transaminases and renal disease. 2 , 5 , 7 Dispenzieri et al. 8 analyzed the clinical spectrum of Castleman’s disease in 113 patients.[pagepress.org] Abstract An HIV positive black African woman presented with widespread lymphadenopathy and pancytopenia that had been ascribed to tuberculosis.[ncbi.nlm.nih.gov]

    Missing: Intrahepatic Cholestasis
  • Primary Myelofibrosis

    This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[aoporphan.com] Polyclonal hyperglobulinemia may be present. Patients with sporadic idiopathic or familial pulmonary hypertension have significant marrow fibrosis.[patient-help.com] The clinical manifestations of PMF include splenomegaly, consequent to extramedullary hematopoiesis, pancytopenias, and an array of potentially debilitating constitutional[ncbi.nlm.nih.gov]

    Missing: Intrahepatic Cholestasis

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