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44 Possible Causes for Involuntary Tongue Protrusion, Sudden Death

  • Rett Syndrome

    death.[ncbi.nlm.nih.gov] […] movements of the upper limbs and tongue protrusion.[ncbi.nlm.nih.gov] Prolonged corrected QT interval (QTc) is also reported and is a speculated cause of sudden death in RTT.[ncbi.nlm.nih.gov]

  • Metoclopramide

    Oral erythromycin and the risk of sudden death from cardiac causes . N Engl J Med 2004; 351 : 1089–96. 20. US Food and Drug Administration.[nature.com] Symptoms of tardive dyskinesia include: grimacing tongue protrusion lip smacking puckering and pursing lips rapid eye blinking rapid movements of the arms, legs, and trunk[nolo.com] These symptoms may include involuntary movements of limbs and facial grimacing, torticollis , oculogyric crisis, rhythmic protrusion of tongue, bulbar type of speech, trismus[rxlist.com]

  • Mesoridazine

    While sudden deaths have been reported with therapeutic doses of mesoridazine and its parent thioridazine, deaths are uncommon in overdose.[ncbi.nlm.nih.gov] The syndrome is characterized by involuntary choreoathetoid movements which variously involve the tongue, face, mouth, lips, or jaw (e.g., protrusion of the tongue, puffing[rxmed.com] Side Effects Serious QT prolongation, agranulocytosis, seizures, neuroleptic malignant syndrome, ventricular arrhythmia, and sudden death.[link.springer.com]

  • Thioridazine

    Risk of sudden death identified by monitoring system . Lancet , 19 , 590 – 591 . Davis , J. & Zhang , M. ( 1988 ) Sudden death in psychiatric patients .[cambridge.org] The syndrome is characterized by involuntary choreoathetoid movements which variously involve the tongue, face, mouth, lips , or jaw (e.g., protrusion of the tongue, puffing[rxlist.com] The event of interest was a diagnosis of ventricular arrhythmia, sudden death, or unexplained or unattended death.[ncbi.nlm.nih.gov]

  • Perphenazine

    The deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature This drug is not approved for the treatment of patients[reference.medscape.com] ¶Case ReportA 39-year-old man was admitted to the emergency room of Methodist Hospital on August 19, 1960, in acute distress because of involuntary protrusion of the tongue[nejm.org] The syndrome is characterized by rhythmical, involuntary movements of the tongue, face, mouth or jaw (e.g., protrusion of tongue, puffing of cheeks, puckering of mouth, chewing[rxlist.com]

  • Molindone

    […] trials; deaths in trials appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature Not approved for treatment of patients[reference.medscape.com] The syndrome is characterized by rhythmical involuntary movements of the tongue, face, mouth or jaw (e.g., protrusion of tongue, puffing of cheeks, puckering of mouth, chewing[rxlist.com] Death typically occurred due to heart failure, sudden death, or infections (primarily pneumonia).[pdr.net]

  • Narcolepsy-Cataplexy Syndrome

    These occur more rarely, but may include: Dependency or abuse Psychosis Mania Aggressive behavior Tourette’s syndrome (rare) Irregular heart rhythms Heart attack Stroke Sudden[verywell.com] Cataplexy in children is slightly different and a variety of symptoms and movements including tongue protrusion and involuntary arm movements have been described.[evelinalondon.nhs.uk] death Seizures Growth suppression with long-term use Allergic reaction Exfoliative dermatitis Low white blood cell count Neuroleptic malignant syndrome Inflammation of cerebral[verywell.com]

  • Trifluoperazine

    Trifluoperazine, a commonly used antipsychotic drug, has been known to induce QT prolongation and torsades de pointes, which can cause sudden death.[ncbi.nlm.nih.gov] The syndrome is characterized by rhythmical involuntary movements of the tongue, face, mouth or jaw (e.g., protrusion of tongue, puffing of cheeks, puckering of mouth, chewing[healthyplace.com] The deaths appeared to be either cardiovascular (eg, heart failure, sudden death) or infectious (eg, pneumonia) in nature.[reference.medscape.com]

  • Chlorpromazine

    Large daily doses of chlorpromazine may cause phenothiazine sudden death syndrome.[ltd.aruplab.com] The syndrome is characterized by rhythmical involuntary movements of the tongue, face, mouth or jaw (e.g., protrusion of tongue, puffing of cheeks, puckering of mouth, chewing[rxlist.com] death/Sudden cardiac death (with possible causes of cardiac origin as well as cases of unexplained sudden death, in patients receiving neuroleptic phenothiazines) (see Section[medicines.org.uk]

  • Haldol

    The sponsor found thirteen reports including TdP, QT prolongation, ventricular arrhythmias and/or sudden death.[psychcentral.com] The syndrome is characterized by rhythmical involuntary movements of tongue, face, mouth or jaw (e. g., protrusion of tongue, puffing of cheeks, puckering of mouth, chewing[healthyplace.com] Tardive dyskinesia is characterized by rhythmic involuntary movements of the tongue, face, mouth, or jaw (e.g., protrusion of the tongue, puffing of cheeks, chewing movements[endoflifecare.tripod.com]

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