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11 Possible Causes for Iron Decreased, Leukocyte Alkaline Phosphatase Decreased, Occult Malignancy

  • Renal Cell Carcinoma

    We describe a unique case of subcutaneous metastasis of sarcomatoid renal cell carcinoma which was the first manifestation of the occult malignancy.[] The blood tests showed the biological signs of malabsorption with profound hypoalbuminemia (15.5 g/L, N 37), decreased serum level of iron (0.52 mg/L, N 7.5) and folic acid[] In cases where the oral lesion represents the initial presentation of an occult primary malignancy, additional workup including full body imaging is recommended to determine[]

  • Adenocarcinoma of the Breast

    Adenocarcinoma of the breast is a term encompassing several types of tumors such as ductal and lobular carcinomas. An asymptomatic painless mass is usually the only symptom in the early stages, whereas an array of constitutional and localized symptoms may be seen in more advanced disease. Mammography and other[…][]

  • Cecal Adenocarcinoma

    Most importantly, for patients with blood cultures that grow C. septicum , a comprehensive search for occult malignancy is imperative, especially for adenocarcinomas in the[] According to this definition, the sign may be present with or without occult malignancy and is detectable on history and physical examination alone.[] malignancy [ 2 ].[]

  • Hodgkin Lymphoma

    The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a[…][]

  • Metastatic Renal Cell Carcinoma

    Int J Mol Sci. 2017 Aug 10;18(8). pii: E1736. doi: 10.3390/ijms18081736. Author information 1 Institute of Biomedicine, Pharmacology, Aarhus University, Wilhelm Meyers Allé 4, DK-8000 Aarhus C, Denmark. 2 Institute of Biomedicine, Pharmacology, Aarhus University, Wilhelm Meyers Allé 4, DK-8000 Aarhus[…][]

  • Leukoerythroblastic Anemia

    Increased C-reactive protein suggests but does not secure a diagnosis of reactive thrombocytosis associated with an occult inflammatory or malignant process.[] ) 2) decreased transport - decreased serum iron TIBC 3) decrased Hb production - anemia, hypochromia, and microcytosis case 2 - Pernicious Anemia - 58 yo female - worsening[] leukocyte alkaline phosphatase score in CML LAP is absent in neoplastic granulocytes and present in benign granulocytes Treatment of CML imatinib mesylate: oral tyrosine[]

  • Bone Marrow Disease

    Some of the transplant centers, including ours, use bone marrow aspiration on related donors to exclude occult hematological malignancies.[] […] numbers of cells. lack of iron making RBC formation difficult spread of other diseases to the bone marrow Diseases of the different cell types Cell types and functions: White[] Molecular genetic studies are usually not performed in patients with mild chronic cytopenia unless there are signs of an occult underlying lymphoma.[]

  • Leukopenia

    […] metastases; and indium-labeled imaging may help locate occult infection.[] iron deficiency anemia.[] […] megakaryocytes Decreased erythroid precursors Leukocyte alkaline High Absent phosphatase Table 9-6.[]

  • Hereditary Neutrophilia

    In addition, a history of smoking, along with evidence for a chronic anxiety state or an occult malignancy, should be sought.[] iron, folate or B12 deficiency or due to autoimmune disease, malnutrition, uraemia, drugs, aplastic anaemia and red cell aplasia.[] […] megakaryocytes Decreased erythroid precursors Leukocyte alkaline High Absent phosphatase Table 9-6.[]

  • Hemoglobin Yakima

    Hosch S, Kraus J, Scheunemann P, Izbicki JR, Schneider C, Schumacher U, Witter K, Speicher MR, Pantel K (2000) Malignant potential and cytogenetic characteristics of occult[] Examination of iron in bone marrow macrophages was traditionally considered the definitive way to demonstrate decreased iron stores.[] The leukocyte alkaline phosphatase score is not elevated when neutrophilia is caused by sickle cell crisis alone when no underlying infection is present.[]