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529 Possible Causes for Iron Deficiency, Photosensitivity

  • Erythropoietic Protoporphyria

    Erythropoietic protoporphyria (EPP) is a rare inherited disease characterized by dermal photosensitivity due to the accumulation of photosensitizer protoporphyrin IX.[ncbi.nlm.nih.gov] These disorders are often associated with iron deficiency anaemia (IDA).[ncbi.nlm.nih.gov] Following sunlight exposure, the resulting photosensitivity is manifested first as pain, later as erythema, edema and dermal lesions.[ncbi.nlm.nih.gov]

  • Acute Hepatic Porphyria

    Differential diagnoses for variagate porphyria and hereditary coproporphyria also include photosensitivity.[orpha.net] Inducing iron deficiency improves erythropoiesis and photo sensivity in congenital erythropoietic porphyria. Blood. 2015;126(2):257–261.[medcraveonline.com] The majority of patients exhibit acute attacks, while 20% can also present with skin-related symptoms, such as photosensitivity and blistering skin lesions.[symptoma.com]

  • Acute Intermittent Porphyria

    Photosensitivity may be controlled by avoiding exposure to light. Removal of the spleen is useful in some cases of the erythropoietic type of porphyria.[medical-dictionary.thefreedictionary.com] These findings suggest that the neurovisceral symptoms of AIP are not associated with generalized hepatic heme deficiency and support the neurotoxicity of ALA and/or PBG.[ncbi.nlm.nih.gov] Acquired forms Porphyria cutanea tarda (PCT) typically is acquired rather than inherited, although the enzyme deficiency may be inherited.[mayoclinic.org]

  • Iron Deficiency

    […] activity of uroporphyrinogen III synthase and the accumulation of nonphysiologic isomer I porphyrin metabolites, resulting in ineffective erythropoiesis and devastating skin photosensitivity[ncbi.nlm.nih.gov] Iron deficiency can develop insidiously leading to increased fatigability, lassitude, poor immunity, irritability, and iron deficiency anemia.[symptoma.com] Iron deficiency anemia is a significant problem worldwide and more so in developing countries, like India.[ncbi.nlm.nih.gov]

  • Porphyria

    The Diagnosis of Photosensitivity. Arch Dermatol. 2000;136(9):1152–1157. doi:10.1001/archderm.136.9.1152 Download citation file: 2019 New![doi.org] And it is known that porphyria, an iron deficiency, which is thought to lie behind the vampire myth, has run in the Royal Family.[web.archive.org] Zn protoporphyrin increases in many conditions other than porphyrias, including iron deficiency, lead poisoning and almost any type of disorder that affects erythrocytes.[web.archive.org]

  • Erythropoietic Porphyria

    […] activity of uroporphyrinogen III synthase and the accumulation of nonphysiologic isomer I porphyrin metabolites, resulting in ineffective erythropoiesis and devastating skin photosensitivity[ncbi.nlm.nih.gov] Here, we describe a case of CEP with infancy onset blistering, photosensitivity, red colored urine and teeth along with scarring but without any feature of hemolysis.[ncbi.nlm.nih.gov] Clinical features include photosensitive blistering and severe anemia. Wood's lamp fluorescence of the diaper is a useful screening test.[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    We reported two cases of SLE with psoriasis vulgaris with clinical manifestations as recurrent erythroderma with photosensitivity.[ncbi.nlm.nih.gov] She was diagnosed with SLE with pernicious anemia and iron deficiency anemia. The rare association of SLE with pernicious anemia was reported previously in few patients.[ncbi.nlm.nih.gov] This photosensitivity can be accompanied by worsening of inflammation throughout the body, called a "flare" of the disease.[web.archive.org]

  • Porphyria Cutanea Tarda

    Systemic lupus erythematosus, of complex pathophysiology and pleomorphic clinical manifestations, is similar to PCT regarding photosensitivity.[ncbi.nlm.nih.gov] deficiency anemia(1), Gene mutation(7), 5-aminolevulinic acid(3), Trace elements(24), Ageing(22), Antioxidation(4), Immunology(601), Nutrition(261), Biochemistry(491), Public[researchmap.jp] Photosensitive skin Photosensitive skin rashes Photosensitivity Sensitivity to sunlight Skin photosensitivity Sun sensitivity [ more ] 0000992 Erythema 0010783 Hyperpigmentation[rarediseases.info.nih.gov]

  • Hypermenorrhea

    Prolonged use of Yarrow may cause photosensitivity of the skin in some people. Therefore, it is advisable not to exceed 15 days of treatment.[naturalexis.com] Iron deficiency anemia may result if the condition goes untreated, as the excessive bleeding can deplete the iron levels of the blood.[wisegeekhealth.com] Low hemoglobin may be the result of insufficient iron. Menorrhagia may deplete iron levels enough to increase the risk of iron deficiency anemia.[pharmacypedia.org]

  • Onycholysis

    Sparfloxacin is an antibiotic in the quinolone group of antibacterial agents, which often induce photosensitive skin reactions, more often phototoxic reactions than photoallergic[ncbi.nlm.nih.gov] As an initial screen for associated systemic disorders, it is reasonable to check a complete blood count and iron panel (for iron deficiency anemia), an antinuclear antibody[dermatologyadvisor.com] Clinical findings include photosensitivity, vesicles, bullae, milia, and scarring in sun-exposed areas.[ncbi.nlm.nih.gov]

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