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1,254 Possible Causes for Iron Deficiency, Splenomegaly

  • Malignant Neoplasm

    Laboratory findings showed no abnormalities, except for a slightly elevated C-reactive protein value and iron deficiency anemia.[ncbi.nlm.nih.gov]

  • Mucolipidosis

    […] conditions 'stand alone', 'walk without support' and 'speak single words' were impaired; however, the frequency of 'heart murmur', 'inguinal hernia' and 'hepatomegaly and/or splenomegaly[ncbi.nlm.nih.gov] While laboratory analyses of blood samples reveal increased levels of gastrin, iron deficiency anemia may also be diagnosed.[symptoma.com] Clinical manifestations, such as ‘heart murmur’, ‘inguinal hernia’ and ‘hepatomegaly and/or splenomegaly’, were found in both ML II and III.[nature.com]

  • Essential Thrombocythemia

    And the clinical characteristics of ET patients, such as WBC counts, hemoglobin level, splenomegaly and thrombosis, were influenced by JAK2V617F mutation burden.[ncbi.nlm.nih.gov] When elderly patients present with persistent thrombocytosis, myeloproliferative disease, iron-deficiency anemia or post-splenectomy status are suspected along with autoimmune[ncbi.nlm.nih.gov] It is difficult to make a diagnosis of ET, because most thrombocythemia are reactive to certain disease conditions including iron deficiency anemia, infection, collagen diseases[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    PNH is associated with abdominal vein thrombosis, which can cause splenomegaly and hypersplenism.[ncbi.nlm.nih.gov] Iron staining of the bone marrow demonstrated the absence of stainable iron and sideroblasts. The patient was diagnosed with iron deficiency anemia.[ncbi.nlm.nih.gov] We describe a patient under treatment with the anti-complement antibody eculizumab who developed pancytopenia, requiring blood transfusions, due to massive splenomegaly.[ncbi.nlm.nih.gov]

  • Schistosomiasis

    Initial investigation showed signs of liver fibrosis, portal hypertension and splenomegaly.[ncbi.nlm.nih.gov] The loss of blood can lead to iron deficiency anemia.[encyclopedia.com] The hepatosplenic form of the disease is characterized by periportal hepatic fibrosis, pre-sinusoidal portal hypertension and splenomegaly.[ncbi.nlm.nih.gov]

  • Pernicious Anemia

    Some people with Pernicious Anemia may have an abnormally enlarged liver (hepatomegaly) or spleen (splenomegaly).[rarediseases.org] An iron deficiency can also disrupt hemoglobin function, causing iron-deficiency anemia.[livestrong.com] Hepatomegaly and splenomegaly may be present.[patient.info]

  • Erythropoietic Protoporphyria

    As hepatic complications worsen the patient will develop splenomegaly, leading to entrapment and hemolysis of erythrocytes.[clinicaladvisor.com] This indicated that anemia in EPP resulted from an absolute iron deficiency.[ncbi.nlm.nih.gov] This disease is characterized by splenomegaly; anemia; photosensitivity; cutaneous lesions; accumulation of hydroxymethylbilane; and increased excretion of uroporphyrins and[icd10data.com]

  • Hereditary Spherocytosis

    Due to the membrane defect, there is increased fragility, hemolytic anemia, marked splenomegaly and hyperbilirubinemia.[ncbi.nlm.nih.gov] Describing 6 typical cases, we demonstrate that occasional normal percentages of hyperchromic red blood cells occurring during phases of anemia and/or iron deficiency are[ncbi.nlm.nih.gov] A total of 153 patients with anemia (33 with HS, 40 with autoimmune hemolytic anemia, 40 with anemia of chronic disease, and 40 with iron deficiency anemia [IDA]) and 140[ncbi.nlm.nih.gov]

  • Thalassemia

    The presence of splenomegaly and the elevation of Hb A(2) and Hb F and the exclusion of a defect of protein of red blood cell (RBC) membranes defined a clinical picture of[ncbi.nlm.nih.gov] CRP C-reactive protein; Hb hemoglobin; IDA iron-deficient anemia; ICP inductively coupled plasma; IE ineffective erythropoiesis; SCD sickle cell disease; sTf transferrin saturation[ncbi.nlm.nih.gov] Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[orpha.net]

  • Autoimmune Hemolytic Anemia

    Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale.[ncbi.nlm.nih.gov] The main types of anemia in patients with Crohn's disease are iron deficiency anemia and anemia of chronic disease.[ncbi.nlm.nih.gov] She was found to have splenomegaly, generalized lymphadenopathy, pancytopenia, and acute hepatic failure.[ncbi.nlm.nih.gov]

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