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97 Possible Causes for Iron Increased, Petechiae, Reticulocyte Count Decreased

  • Aplastic Anemia

    For example, for a person with anemia, an inappropriately low reticulocyte count often indicates decrease in red blood cell production in the bone marrow .[labtestsonline.org] We studied 4 adult AA patients who had transfusion-induced iron overload and showed hematological improvement after ICT with oral deferasirox.[ncbi.nlm.nih.gov] Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia (infections).[merckmanuals.com]

  • Pernicious Anemia

    Petechiae in the mammillary bodies. WKS, acute lesion. Periaqueductal lesions. WKS, acute lesion. Periaqueductal lesions. WKS, burned out lesion. WKS, burned out lesion.[neuropathology-web.org] Values obtained before treatment with cyanocobalamin were compared with those found during peak reticulocyte count.[ncbi.nlm.nih.gov] Individuals suffering iron deficiency might take oral iron supplements and increase their dietary iron intake, while individuals suffering from pernicious anemia might receive[livestrong.com]

  • Leukemia

    These were petechiae/purpura (category derived from ‘petechiae’, ‘purpura’ and ‘petechiae/purpura’), mucosal bleeding (including ‘mucosal bleeding’ and ‘bleeding gums’), anorexia[doi.org] An additional eight features were present in a third to a half of children: recurrent infections (49%), fatigue (46%), limb pain (43%), hepatosplenomegaly (42%), bruising/petechiae[ncbi.nlm.nih.gov] "Petechiae usually appears on the lower extremities," Wadleigh adds.[prevention.com]

  • Acute Myelocytic Leukemia

    An iron stain usually shows increased iron stores and may show ring sideroblasts (Figure 2, B [inset]).[archivesofpathology.org] Thrombocytopenia often causes petechiae on the lower limbs. DIC may aggravate the situation and cause larger lesions.[patient.info] The potential for neurotoxicity has aroused concern about the use of high-dose cytarabine in elderly patients who, ironically, have a higher likelihood of having drug-resistant[doi.org]

  • Acute Myeloid Leukemia with Myelodysplasia-related Changes

    Mitochondrial pathology in MDS is suggested by abnormal mitochondrial iron accumulation, increased apoptosis, and a high frequency of acquired mitochondrial DNA mutations[ncbi.nlm.nih.gov]

  • Iron Deficiency Anemia

    Normal 0.5-1.5% Hypoprolifearative: Decreased reticulocytes Bone marrow unable to produce requisite number of RBC's Lack of essential substance (iron, B12, folate) or invasion[meddean.luc.edu] This is because your need for iron increases during these times of growth and development.[web.archive.org] You may have tiny red dots on your skin, called petechiae (pe-TEEK- ee-ay). These are commonly found on your lower legs. This is a sign of low blood platelets.[chemocare.com]

  • Chronic Kidney Insufficiency

    Because of increased iron utilization with stimulated erythropoiesis, iron stores must be replaced, often requiring parenteral iron.[merckmanuals.com] […] haemorrhage Subdural haematoma Epistaxis Haematuria Ecchymosis Purpura Bleeding from the gums Gingival bleeding Genital bleeding Haemoptysis Telangiectasia Haemarthrosis Petechiae[academic.oup.com] Iron therapy can help increase levels of iron in the body when EPO therapy alone is not effective. Vitamin D helps keep bones strong and healthy.[uwhealth.org]

  • Myelodysplasia

    Red blood cells contain iron, so if you have a lot of blood transfusions, the level of iron in your body will increase.[macmillan.org.uk] ., bruising and/or petechiae) may cause patient distress.[ncbi.nlm.nih.gov] Petechiae, ecchymoses, and nose and gum bleeding are common manifestations of a low platelet count.[emedicine.medscape.com]

  • Primary Myelofibrosis

    , and polychromatophilia and very elevated reticulocyte counts can occur. 263,264 The antiglobulin (Coombs) test usually is negative, but red cell autoantibodies can develop[patient-help.com] […] for the increase in hemoglobin levels.[ncbi.nlm.nih.gov] Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy[orpha.net]

  • Sideroblastic Anemia

    RBC indices reveal a decreased MCV, MCH, and a decreased reticulocyte count which correlates with Iron deficiency anemia.[usmleforum.com] Decreased ferritin increases synthesis of transferrin (increasing TIBC); such as seen in iron deficiency anemia.[forums.studentdoctor.net] You may also note slight jaundice, caused by excessive iron accumulation in the liver, and petechiae or bruises, caused by thrombocytopenia.[encyclopedia.lubopitko-bg.com]

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