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271 Possible Causes for Iron Increased, Progressive Polyneuropathy

  • Vitamin B12 Deficiency

    peripheral neuropathy, and spinal degeneration.[] You may also develop anemia due to iron deficiency and you can read my other post about the top signs of iron deficiency and how to increase iron levels in your blood .[] Deficiency and How To Increase Iron Levels In Your Blood Common Defficincies Almost Everyone Has (and doesn’t know about it) Top Signs That You Have Magnesium Deficiency[]

  • Chronic Alcoholism

    Coexisting iron accumulation or chronic hepatitis C increases risk of hepatocellular carcinoma.[] Other factors that may trigger type 1 PCT include oestrogen, iron and viral infections (especially hepatitis C).[] A diet high in unsaturated fat increases susceptibility, as does obesity.[]

  • Pernicious Anemia

    Individuals suffering iron deficiency might take oral iron supplements and increase their dietary iron intake, while individuals suffering from pernicious anemia might receive[] Eat more meats for better iron absorption. Vitamin C also increases iron absorption. Try eating citrus fruits or bell pepper when you consume your iron.[] Since rapid cell regeneration increases the patient’s iron and folate requirements, supplemental iron and folic acid replacement is necessary to prevent iron deficiency anemia[]

  • Heavy Metal Poisoning

    In addition, non-inflammatory degenerative disease of the sensorimotor nerves (sensorimotor polyneuropathy) may advance to progressive deterioration (atrophy).[] Low iron increases toxicity of cadmium and lead, causing impaired cognitive function.[] . • Data suggests that low dietary intake of vitamin D may increase accumulation of lead in bones, whereas low dietary intake of vitamin C and iron may increase lead levels[]

  • Diabetes Mellitus

    Hemochromatosis is an inherited condition associated with increased iron storage. Iron buildup can damage the pancreas and other organs.[] Delay in starting GFD increases the risk of osteoporosis, gastrointestinal malignancies, iron deficiency anemia, infertility, and other autoimmune disorders.[]

  • Vasculitis

    Neuropathy Sensory or Sensory-Motor General patterns Mononeuritis multiplex (13%) Asymmetric polyneuropathy (85%) Distal symmetric polyneuropathy (2%) More slowly progressive[] Abstract Deferasirox is an iron chelator agent used in the treatment of diseases with iron overload, such as thalassemia and myelodysplastic syndrome.[] CIDP Peripheral Nerve Specific Vasculitis 2 Epidemiology: Females & Males Onset Age: Mean 59 years; Range 22 to 70 years Pain & Sensory loss Progression: 3 months to 5 years[]

  • Occult Malignancy

    , possibly contributing to the start and promotion of the tumour process while also instigating lipid oxidative lesions, resulting in an increased expression of tissue factor[] […] processes and metastatic disease; (4) plateletrich microthrombotic processes; (5) activation of oncogenes that induce clotting; (6) toxicity from high environmental levels of iron[]

  • Guillain-Barré Syndrome

    Guillain-Barré syndrome is a rare condition in pregnancy which is characterised by symmetrical progressive ascending polyneuropathy.[] Pradal, Abnormally increased iron concentration in basal ganglia in Shy-Drager syndrome MR imaging and autonomic study: RM imagem e estudo autonômico, Arquivos de Neuro-Psiquiatria[] An 81-year-old man presented with fever, confusion and rapidly-progressive flaccid tetraparesis.[]

  • Acute Intermittent Porphyria

    The electromyogram showed sensorimotor polyneuropathy markedly of movement, with axonal character of symmetric distribution and severe axonal loss in distal and proximal areas[] […] concentration was slightly elevated; and (f) heme oxygenase I mRNA was increased approximately three-fold.[] Ferrokinetic studies in one patient also demonstrated decreased erythropoiesis (plasma iron turnover was 70 per cent of normal).[]

  • Thiamine Deficiency

    Nerve conduction studies were consistent with axonal, length-dependent polyneuropathy.[] […] is one potential way of increasing micronutrient intake in resource limited populations....[] Infants and young children are also at increased risk if they continue to breastfeed after 6 months of age without iron supplementation 21, or if they consume weaning foods[]

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