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168 Possible Causes for Iron Increased, Reticulocyte Count Decreased

  • Chronic Alcoholism

    Coexisting iron accumulation or chronic hepatitis C increases risk of hepatocellular carcinoma.[merckmanuals.com] Other factors that may trigger type 1 PCT include oestrogen, iron and viral infections (especially hepatitis C).[dermnetnz.org] A diet high in unsaturated fat increases susceptibility, as does obesity.[merckmanuals.com]

  • Iron Deficiency Anemia

    Normal 0.5-1.5% Hypoprolifearative: Decreased reticulocytes Bone marrow unable to produce requisite number of RBC's Lack of essential substance (iron, B12, folate) or invasion[meddean.luc.edu] This is because your need for iron increases during these times of growth and development.[web.archive.org] Increased demand: Iron deficiency can occur during rapid periods of growth.[irondisorders.org]

  • Pernicious Anemia

    Values obtained before treatment with cyanocobalamin were compared with those found during peak reticulocyte count.[ncbi.nlm.nih.gov] Individuals suffering iron deficiency might take oral iron supplements and increase their dietary iron intake, while individuals suffering from pernicious anemia might receive[livestrong.com] Response should be monitored by reticulocyte counts, lactic dehydrogenase (LDH), and an appropriate rise in hemoglobin levels.[emedicine.medscape.com]

  • Aplastic Anemia

    For example, for a person with anemia, an inappropriately low reticulocyte count often indicates decrease in red blood cell production in the bone marrow .[labtestsonline.org] We studied 4 adult AA patients who had transfusion-induced iron overload and showed hematological improvement after ICT with oral deferasirox.[ncbi.nlm.nih.gov] Stainable iron is usually increased; however, the presence of increased ringed sideroblasts suggests a diagnosis of MDS.[cancertherapyadvisor.com]

  • Folate-Deficiency Anemia

    Significant blood test findings include macrocytosis, decreased reticulocyte count, abnormal platelets, and a serum folate less than 4 mg/ml.[innvista.com] Dangers of anaemia and iron deficiency less iron passing from mother to foetus so the newborn has low iron stores increased risk of blood loss during and after delivery, and[southsudanmedicaljournal.com] Iron deficiency anemia is due to insufficient iron, either from inadequate dietary intake or from increased iron losses.[livestrong.com]

  • Sideroblastic Anemia

    RBC indices reveal a decreased MCV, MCH, and a decreased reticulocyte count which correlates with Iron deficiency anemia.[usmleforum.com] Decreased ferritin increases synthesis of transferrin (increasing TIBC); such as seen in iron deficiency anemia.[forums.studentdoctor.net] , and increased IRP2 levels, indicative of relative cytosolic iron depletion, were observed together with mitochondrial iron overload.[ncbi.nlm.nih.gov]

  • Acute Myelocytic Leukemia

    An iron stain usually shows increased iron stores and may show ring sideroblasts (Figure 2, B [inset]).[archivesofpathology.org] The potential for neurotoxicity has aroused concern about the use of high-dose cytarabine in elderly patients who, ironically, have a higher likelihood of having drug-resistant[doi.org] […] in the patients who received high-dose cytarabine in our trial 45 ; the risk of neurotoxicity was less than 1 percent if none or one of these factors was present, but it increased[doi.org]

  • Leukemia

    Leukemia is cancer of the blood forming tissues that also affects the bone marrow and the lymphatic system. Such a type of cancer causes abnormal development of cells that gradually enter the bloodstream. Symptoms of leukemia vary with the type. The common symptoms of the disease include the following: Undue[…][symptoma.com]

  • Acute Myeloid Leukemia with Myelodysplasia-related Changes

    Mitochondrial pathology in MDS is suggested by abnormal mitochondrial iron accumulation, increased apoptosis, and a high frequency of acquired mitochondrial DNA mutations[ncbi.nlm.nih.gov]

  • Iron Deficiency

    The reticulocyte hemoglobin content (CHr, measured by some automated hematology analyzers) decreases, and the reticulocyte count falls.[cancertherapyadvisor.com] Iron deficiency is a lack of iron in the body resulting from inadequate iron intake, increased iron loss, or excessive iron requirements of which iron deficiency anaemia ([bestpractice.bmj.com] For example, for a person with anemia, an inappropriately low reticulocyte count often indicates decrease in red blood cell production in the bone marrow .[labtestsonline.org]

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