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160 Possible Causes for Iron Increased, Reticulocyte Count Decreased, Severe Anemia

  • Iron Deficiency Anemia

    OBJECTIVE: To evaluate the proportion of children with moderate to severe iron-deficiency anemia who have associated celiac disease.[ncbi.nlm.nih.gov] Normal 0.5-1.5% Hypoprolifearative: Decreased reticulocytes Bone marrow unable to produce requisite number of RBC's Lack of essential substance (iron, B12, folate) or invasion[meddean.luc.edu] This is because your need for iron increases during these times of growth and development.[web.archive.org]

  • Aplastic Anemia

    OVERVIEW: What every practitioner needs to know about severe aplastic anemia Are you sure your patient has severe aplastic anemia?[clinicaladvisor.com] For example, for a person with anemia, an inappropriately low reticulocyte count often indicates decrease in red blood cell production in the bone marrow .[labtestsonline.org] We studied 4 adult AA patients who had transfusion-induced iron overload and showed hematological improvement after ICT with oral deferasirox.[ncbi.nlm.nih.gov]

  • Pernicious Anemia

    Here, we report a rare coincidence of heterozygous hemoglobinopathy (Hb) Stanleyville II and severe pernicious anemia due to autoimmune gastritis.[ncbi.nlm.nih.gov] Values obtained before treatment with cyanocobalamin were compared with those found during peak reticulocyte count.[ncbi.nlm.nih.gov] Individuals suffering iron deficiency might take oral iron supplements and increase their dietary iron intake, while individuals suffering from pernicious anemia might receive[livestrong.com]

  • Leukemia

    People may need blood transfusions if leukemia has caused severe anemia. They may need antibiotics if infections develop.[merckmanuals.com] Severe in 90% Severe in 90% Mild in about 50% Mild in 80% Platelets Low in 80% Low in 90% Low in 20 to 30% High in 60% Low in 10% Lymphadenopathy Common Occasional Common[msdmanuals.com] […] in myeloblasts Occasionally hemolytic anemia and hypogammaglobulinemia Low leukocyte alkaline phosphatase level Philadelphia chromosome–positive in 90% Acute leukemias Chronic[merckmanuals.com]

  • Acute Myelocytic Leukemia

    anemia characteristic of HP failure, an expected feature of AML • Polychromasia: reduced, since anemia is result of bone marrow production failure • Other RBC pathology:[slideshare.net] An iron stain usually shows increased iron stores and may show ring sideroblasts (Figure 2, B [inset]).[archivesofpathology.org] The potential for neurotoxicity has aroused concern about the use of high-dose cytarabine in elderly patients who, ironically, have a higher likelihood of having drug-resistant[doi.org]

  • Sideroblastic Anemia

    The female infant developed moderately severe anemia at 6 months of age, which did not improve despite adequate nutritional support.[ncbi.nlm.nih.gov] RBC indices reveal a decreased MCV, MCH, and a decreased reticulocyte count which correlates with Iron deficiency anemia.[usmleforum.com] Decreased ferritin increases synthesis of transferrin (increasing TIBC); such as seen in iron deficiency anemia.[forums.studentdoctor.net]

  • Folate-Deficiency Anemia

    Folate-deficiency anemia usually develops slowly. At first, children with anemia don’t have symptoms. If untreated and severe, they become tired and fussy.[fairview.org] Significant blood test findings include macrocytosis, decreased reticulocyte count, abnormal platelets, and a serum folate less than 4 mg/ml.[innvista.com] Dangers of anaemia and iron deficiency less iron passing from mother to foetus so the newborn has low iron stores increased risk of blood loss during and after delivery, and[southsudanmedicaljournal.com]

  • Iron Deficiency

    When severe, anemia may cause shortness of breath, dizziness, and a rapid heart rate. Occasionally, severe anemia causes chest pain and heart failure.[merckmanuals.com] The reticulocyte hemoglobin content (CHr, measured by some automated hematology analyzers) decreases, and the reticulocyte count falls.[cancertherapyadvisor.com] Iron deficiency is a lack of iron in the body resulting from inadequate iron intake, increased iron loss, or excessive iron requirements of which iron deficiency anaemia ([bestpractice.bmj.com]

  • Chronic Alcoholism

    Alcoholics have a higher risk of severe complications after all types of surgery, and thus show a much slower recovery rate after major operations.[searidgealcoholrehab.com] Coexisting iron accumulation or chronic hepatitis C increases risk of hepatocellular carcinoma.[merckmanuals.com] Health troubles can range in severity, but the following health conditions and diseases may manifest due to chronic, heavy alcohol abuse: Cardiovascular disease Anemia Dementia[americanaddictioncenters.org]

  • Hereditary Spherocytosis

    In immunocompromised individuals, chronic infections can occur and cause a severe, persistent anemia.[ncbi.nlm.nih.gov] At 1 year following partial splenectomy, mean hemoglobin significantly increased by 3.0 1.4 g/dL (n 52), reticulocyte count decreased by 6.6% 6.6% (n 41), and bilirubin level[ncbi.nlm.nih.gov] Indications for laparoscopic removal of the spleen included anemia unresponsive to iron supplementation in eight patients (66.6 %) with increase need for red cells transfusions[ncbi.nlm.nih.gov]

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