Irritability: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Irritability

Constipation

Clinical study results in patients with Chronic Idiopathic Constipation (CIC) and Irritable Bowel Syndrome with Constipation (IBS-C) are also reviewed. [ncbi.nlm.nih.gov]

BACKGROUND AND AIM: Linaclotide is a guanylate cyclase-C agonist approved in multiple countries to treat irritable bowel syndrome with constipation (IBS-C). [ncbi.nlm.nih.gov]

AIM: This meta-analysis analyzed the efficacy and safety of traditional Chinese medicine (TCM) for the treatment of irritable bowel syndrome with constipation (IBS-C). [ncbi.nlm.nih.gov]

Insomnia

It is associated with daytime symptoms such as irritability and fatigue. The February 20, 2013, issue of JAMA includes an article about insomnia. [doi.org]

It typically causes excessive daytime sleepiness, irritability, and lack of energy. [doi.org]

Nonrestorative sleep—individuals feel that sleep is unrefreshing or of poor quality Daytime fatigue and/or sleepiness Difficulty concentrating and remembering Changes in mood—irritability [doi.org]

Bronchitis

These lung irritants also can make symptoms worse. [web.archive.org]

It occurs if the lining of the bronchial tubes is constantly irritated and inflamed, causing a long-term cough with mucus. [web.archive.org]

After a long period of irritation: Excess mucus is produced constantly The lining of the airways becomes thickened An irritating cough develops Air flow may be hampered The [web.archive.org]

Hypoglycemia

An infant presented with short history of jaundice and irritability, examination showed soft hepatomegaly. [ncbi.nlm.nih.gov]

[…] behavior lightheadedness unsteady movement inability to concentrate personality changes headache restlessness depressed mood tingling in the hands, feet, lips, or tongue irritability [glucagenhypokit.com]

You may feel suddenly overwhelmed, frustrated, angry, anxious, or irritated, or in some cases, irrational. [healthcentral.com]

Vaginitis

This irritation of the vagina or vulva (the outside opening of the vagina) can affect anyone, from teens to menopausal grandmothers. [premierhealth.com]

Follow these simple tips to avoid irritation and infection: Wash the vaginal area every day, using a mild, unscented soap. [premierhealth.com]

When the walls of the vagina become inflamed, because some irritant has disturbed the balance of the vaginal area, vaginitis can occur. [columbiadoctors.org]

Vulvitis

It means that on some occasions we need to primarily treat a contact or irritant dermatitis rather than rushing out to get the anti-yeast cream. What Are The Irritants? [wdxcyber.com]

Contact Dermatitis (Irritant or Allergic Vulvitis) Contact dermatitis is a rash that results when the skin makes contact with an irritating substance. [colposcopycenter.com]

A 50-year-old female with longstanding complaints of spotting, vulvar dryness, irritation, and dyspareunia presented with circumscribed, purpuric, erythematous vulvar patches [ncbi.nlm.nih.gov]

Alcohol Abuse

Found that when the effects of alcohol were wearing off, you had withdrawal symptoms, such as trouble sleeping, shakiness, irritability, anxiety, depression, restlessness, [niaaa.nih.gov]

They include trouble sleeping, shakiness, irritability, anxiety, depression, restlessness, nausea, and sweating. [medlineplus.gov]

Acute Bronchitis

mucus production worsens and an irritating cough develops. [inogen.com]

Viruses or bacteria can easily infect the irritated bronchial tubes. When this happens, the condition worsens and lasts longer. [agingcare.com]

These lung irritants also can make symptoms worse. [healthcare.utah.edu]

Substance Abuse

"This can include increased irritability, mood swings, angry outbursts, and patterns of isolation." [bustle.com]

These symptoms can include : Loss of interest and pleasure Irritability and anger Changes in appetite Sleep problems Fatigue Slow movement and thinking Feelings of worthlessness [centerforanxietydisorders.com]

(suggestive of cocaine insufflation) Conjunctival irritation (suggestive of exposure to marijuana smoke) Labile blood pressure, tachycardia (suggestive of alcohol withdrawal [aafp.org]

Cystitis

Interstitial cystitis is a painful condition in which the bladder wall becomes irritated and inflamed. [everydayhealth.com]

Finally, avoid any products that irritate the area. [healthline.com]

Interstitial Cystitis Diet Avoiding foods that cause bladder irritation can help to relieve some symptoms of interstitial cystitis. [everydayhealth.com]

Insect Bite

That way, you will get the most benefit and to prevent issues like skin irritation. [theheartysoul.com]

Expert verdict: The crotamiton works as a 'counter irritant', irritating the skin receptors to the point where they stop working, so no longer relay the alternating temperature [dailymail.co.uk]

When you remove the irritant, the body stops producing the reaction that is causing you to itch and swell. [amazon.com]

Vaginal Candidiasis

[…] alone (27%) or irritation plus vaginal discharge (25%). [ncbi.nlm.nih.gov]

In vitro analyses (MTT assay, viscosity measurement, mucoadhesion, ex vivo permeation, etc.) and in vivo studies (bioadhesion, irritation potential and fungal clearance kinetics [ncbi.nlm.nih.gov]

Irritant dermatitis Irritation Burning Erythema of vulva and/or vestibule Normal pH Negative microscopy Negative fungal culture Removal of potential irritants Topical corticosteroid [aafp.org]

Dysthymic Disorder

In children, dysthymia may present as irritable mood, and a duration of symptoms of only one year is required to make the diagnosis. [ncbi.nlm.nih.gov]

Depressed mood, irritability, loss of energy and fatigue, guilt and low self-esteem were present in more than 70% of the subjects. [ncbi.nlm.nih.gov]

A symptomatic profile in the group with ID showed that intrapsychic and cognitive symptoms, such as depressed mood, irritability, pathological guilt and low self-image, were [ncbi.nlm.nih.gov]

Rosacea

This may help you figure out what irritates your skin. Use a sunscreen every day. [niams.nih.gov]

The most common adverse effects are irritation, xerosis, and burning. [ncbi.nlm.nih.gov]

Other Medical Problems Other medical problems related to rosacea In addition to red, irritated skin, rosacea can cause eye problems. [niams.nih.gov]

Gingivitis

Tartar makes plaque more difficult to remove, creates a protective shield for bacteria and causes irritation along the gumline. [mayoclinic.org]

Contact your dentist if swelling and irritation worsen during your pregnancy or continue after delivery. [americanpregnancy.org]

A 51-year old woman was referred to a specialized dentist because of consistent irritative buccal gingival hyperplasia that did not react to conservative and microbial treatment [ncbi.nlm.nih.gov]

Iron Deficiency Anemia

Areca nut is considered the primary etiology along with other local irritants like capsaicin, pungent and spicy food, nutritional deficiency, defective iron metabolism, collagen [ncbi.nlm.nih.gov]

Supplements can cause irritation of the stomach and cause stools to become black in color. [illinoiscancercare.com]

Iron supplements can cause irritation of the stomach and discoloration of bowel movements. [chop.edu]

Otitis Media

OME is more common than AOM, and may be caused by viral upper respiratory infections, allergies, or exposure to irritants (such as cigarette smoke). [web.archive.org]

[…] leading to a difficult diagnosis Irritability In neonates, irritability, excessive crying, feeding difficulty may the only signs of acute infection leading to a difficult [medicaljoyworks.com]

Irritability: Any kind of continuing pain may cause irritability in children and adults. [my.clevelandclinic.org]

Chronic Alcoholism

[…] neglect of physical appearance and proper nutrition, alcohol-related illness (such as hepatitis or cirrhosis of the liver), and moderate to severe withdrawal symptoms (such as irritability [merriam-webster.com]

They may wake up next morning with a headache, feeling irritable, but that is as far as it goes. [eskimo.com]

They include nausea, irritability, shakiness, depression, fatigue, anxiety, coarse tremor, and excitability. [bestpractice.bmj.com]

Brain Concussion

irritability, tearfulness or feeling down Sensitive to light and sound Suffer from cloudy thinking If these sequelae exist then bed rest is not necessary, but it is good [braininjury-explanation.com]

Post-concussion syndrome can include physical, cognitive, and emotional problems, including: Headache Dizziness Difficulty concentrating or completing tasks Irritability The [concussion.weillcornell.org]

Move slowly and constantly be aware of your surroundings Do not climb stepladders or work from heights Stress, irritability, sadness and anxiety are common and normal reactions [brainstreams.ca]

Common Cold

The person may cough from irritation and from phlegm collecting in the throat. [uofmhealth.org]

Firstly, the cumulative throat irritation score was used in two trials ( Sperber 1992 ; Winther 2001 ). [doi.org]

Kali bichromicum This helps relieve thick, greenish, irritating nasal discharge. [uofmhealth.org]

Head Trauma

Being irritable and grumpy. Tiredness. Poor appetite. Some difficulty concentrating. [patient.info]

Your baby may have one or more of these early symptoms: loss of consciousness drowsiness dizziness confusion vomiting irritability drainage, clear or bloody, from his nose [babycenter.com]

Common questions our doctors are asked How do I know if my child’s irritability and mood swings are because he is tired after the head injury, or something to worry about? [rch.org.au]

Chronic Obstructive Pulmonary Disease

The main cause of COPD is long-term exposure to substances that irritate and damage the lungs. This is usually cigarette smoke. [medlineplus.gov]

The small, hair-like structures on the inside of the airways (called cilia) might be damaged by the irritation. [my.clevelandclinic.org]

Chronic bronchitis Chronic bronchitis is irritation and inflammation (swelling) of the lining in the bronchial tubes (air passages). [my.clevelandclinic.org]

Dermatitis

Acute irritant contact dermatitis occurs after an exposure to a strong irritant or a caustic chemical (e.g., acid or alkali; Figure 2 ). [doi.org]

We included nine RCTs involving 2888 participants without occupational irritant hand dermatitis (OIHD) at baseline. [ncbi.nlm.nih.gov]

[…] skin changes from irritant contact dermatitis. [doi.org]

Stomatitis

Mechanical or chemical irritation, ill-fitting dentures, and dental fillings can induce irritant contact stomatitis. [ncbi.nlm.nih.gov]

irritation. [topdentists.com]

These can include biting or chewing on the inside of the mouth, tongue, or lip, irritation caused by braces or a jagged tooth, irritation caused by chewing tobacco, burning [study.com]

Sinusitis

Exposure to irritants and allergens: People with allergies and asthma are more likely to develop chronic sinusitis because these conditions can increase pressure and irritation [medicalnewstoday.com]

Top of Page Antibiotics Will Not Help if… When sinusitis is caused by a virus or irritation in the air (like cigarette smoke), antibiotics will not help it get better. [web.archive.org]

Tobacco smoke and air contaminants can irritate and inflame your lungs and nasal passages. Use a humidifier. [mayoclinic.com]

Esophagitis

Esophagitis is a condition in which the lining of the esophagus becomes swollen, inflamed, or irritated. [nlm.nih.gov]

Known to irritate the GI tract. [en.wikipedia.org]

Esophagitis is caused by an infection or irritation in the esophagus. An infection can be caused by bacteria, viruses, fungi, or diseases that weaken the immune system. [webmd.com]

Crack Ingestion

Binge use of the drug can cause adverse effects, such as anxiety, irritability, and restlessness. [hiredpower.com]

After use of crack cocaine, crack cocaine symptoms include the following: 2 Crack cocaine craving Depression Agitation, anxiety, anger, irritability Fatigue, lack of motivation [healthyplace.com]

First-wave physical effects may include anxiety, elevated heart rate, and blood pressure, increased body temperature, irritability, dilated pupils, and restlessness. [hiredpower.com]

Anxiety Disorder

His friends have noticed that Mitchell is irritable and angry most of the time, but when they try to distract him or ask him to hang out he blows them off. [anxietybc.com]

At least 3 key symptoms out of a possible 6 are required to make a diagnosis: restlessness or nervousness, easy fatigability, poor concentration, irritability, muscle tension [bestpractice.bmj.com]

Thus, a modified single factor model allowing the error terms of items associated with relaxing difficulties and irritability to covary was an appropriate solution. [ncbi.nlm.nih.gov]

Upper Respiratory Infection

Minor nasal discomfort and/or irritation was the only side effect reported by a minority of participants. [ncbi.nlm.nih.gov]

Irritable Bowel Syndrome (IBS) can have a major impact on your quality of life. .. Learn about the amazing health benefits of figs. These tiny delicious fruits are.. [netmeds.com]

[…] foreign virus causing: An increase in mucus production (runny nose) Swelling of the lining of the nose, making it hard to breathe and causing congestion Sneezing from the irritation [coppellfamilymedicine.com]

Alzheimer Disease

In early stages of the disease, people may experience personality changes such as irritability, anxiety or depression. [web.archive.org]

AD can also affect a person’s mood, and people with AD may become depressed, anxious, paranoid or irritable. [memory.ucsf.edu]

Middle or Moderate stage: memory loss worsens, progressive cognitive impairment, the patient gets easily irritated, disoriented and agitated. [flexikon.doccheck.com]