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150 Possible Causes for Irritability, Loss of Motor Skills, Rhabdomyolysis

  • Alcohol Abuse

    There may be a dramatic loss of motor skills and coordination. Vision may be significantly blurred.[americanaddictioncenters.org] Found that when the effects of alcohol were wearing off, you had withdrawal symptoms, such as trouble sleeping, shakiness, irritability, anxiety, depression, restlessness,[niaaa.nih.gov] Rhabdomyolysis is a severe and life-threatening condition in which skeletal muscle is damaged.[ncbi.nlm.nih.gov]

  • Chronic Alcoholism

    skills, or slurred speech.[cdc.gov] […] neglect of physical appearance and proper nutrition, alcohol-related illness (such as hepatitis or cirrhosis of the liver), and moderate to severe withdrawal symptoms (such as irritability[merriam-webster.com] Of five chronic alcoholics with acute skeletal muscle necrosis (rhabdomyolysis) three developed acute heart failure with disturbances of rhythm and conduction.[ncbi.nlm.nih.gov]

  • Leigh's Disease

    The symptoms of the disease usually progress at a rapid rate, with the earliest signs potentially being poor sucking ability and a loss of motor skills and head control.[disabled-world.com] Symptoms usually begin between ages of three months and two years and include loss of appetite, vomiting, irritability and seizure activity.[wikidata.org] […] are a few reports regarding the use of succinylcholine in patients with Leigh disease, we would suggest that succinylcholine be avoided because of the potential risks of rhabdomyolysis[saudija.org]

  • Alzheimer Disease

    However, as MCI progresses to Alzheimer disease, memory loss becomes more severe, and language, perceptual, and motor skills deteriorate.[britannica.com] In early stages of the disease, people may experience personality changes such as irritability, anxiety or depression.[web.archive.org] Rhabdomyolysis associated with hydroxymethylglutaryl-coenzyme A reductase inhibitors. Am Heart J 2004 Jun; 147(6): 956–65 PubMed CrossRef Google Scholar 108.[oadoi.org]

  • Glutaric Aciduria

    […] of motor skills and convulsions resulting in bilateral striatal injury with severe secondary dystonia and occasionally subdural and retinal hemorrhage.[orpha.net] Other clinical features included irritability (12/13), neurologic depression (11/13), and hypotonia (7/13). All patients evolved to dystonic tetraparesis.[ncbi.nlm.nih.gov] KEYWORDS: glutaric aciduria type II; multiple acyl Co-A dehydrogenase deficiency; myopathy; rhabdomyolysis[ncbi.nlm.nih.gov]

  • Dementia

    The former are characterized predominantly by memory loss, accompanied by impairment in other cognitive functions or "domain," such as language function ( aphasia ), skilled[my.clevelandclinic.org] We present the case of a 34-year-old Jordanian woman who was referred to mainstream mental health services because of irritability, agitation, loss of appetite, withdrawal[ncbi.nlm.nih.gov] The SAEs considered to be treatment related in the atorvastatin group were hepatitis, acute renal failure/rhabdomyolysis/pancreatitis, abdominal pain/nausea/chest discomfort[doi.org]

  • Duchenne Muscular Dystrophy

    […] of motor skills development fatigue rapidly worsening weakness in the legs, pelvis, arms, and neck DMD is a genetic disease.[healthline.com] Fecal transplant is used to treat gut infections and is now being studied as a treatment for obesity, urinary tract infections, irritable bowel syndrome and more.[nytimes.com] DMD is usually a challenge for the anaesthesiologist, with poor cardiac function, a high risk of developing rhabdomyolysis, and the probable life-threatening complications[ncbi.nlm.nih.gov]

  • Hepatic Encephalopathy

    There is usually asterixis and difficulty with writing and other fine motor skills. Patients are moderately obtunded, confused, and disoriented.[enotes.tripod.com] We present a case of decompensated liver cirrhosis with ascites, which had history of asterixis, impaired balance with swaying gait along with mild irritability since 1 month[ncbi.nlm.nih.gov] Syunsuke Nakajima, Masami Abe, Yayoi Hosoki, Takaaki Ohtake, Tsuneshi Fujii, Mikihiro Fujiya, Yutaka Kohgo and Chitomi Hasebe, Conservative treatment of lamivudine-induced rhabdomyolysis[doi.org]

  • Subacute Sclerosing Panencephalitis

    All children showed a progressive course of dementia, loss of motor skills and epilepsy.[ncbi.nlm.nih.gov] Because these patients may be unable to express symptoms, increased intracranial pressure should be considered in the presence of irritability or frequent myoclonia.[ncbi.nlm.nih.gov] He developed adult respiratory distress syndrome and renal failure due to rhabdomyolysis. Creatine kinase levels were 47,000.[ncbi.nlm.nih.gov]

  • Marchiafava Bignami Disease

    Loss of purposive hand movements & acquired fine motor manipulative skills with subsequent development of stereotyped hand movements.[rxpgonline.com] There were no lateralizing deficits and no signs of meningeal irritation.[indianjpsychiatry.org] […] after admission we started a small dose citalopram (SSRI) to treat his depression and within 24-hours he developed symptoms and signs suggestive of serotonin syndrome with rhabdomyolysis[neurology.org]

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