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107 Possible Causes for Irritability, Nocturnal Leg Cramp, Weight Loss

  • Chronic Alcoholism

    The first had been admitted with confusion and weight loss, the second with hypotension and sepsis, and the third with confusion and hypoglycaemia-induced seizures.[ncbi.nlm.nih.gov] […] neglect of physical appearance and proper nutrition, alcohol-related illness (such as hepatitis or cirrhosis of the liver), and moderate to severe withdrawal symptoms (such as irritability[merriam-webster.com] OBJECTIVE: Diarrhea, weight loss and osteoporosis are prominent symptoms and clinical signs of alcoholism.[ncbi.nlm.nih.gov]

  • Hyperthyroidism

    A 28-year-old woman presented with weight loss and tiredness. Investigations revealed hyperthyroidism. She was commenced on treatment and later became pregnant.[ncbi.nlm.nih.gov] This leads to a wide range of symptoms including weight loss, increased appetite, increased sweating, intolerance to heat, anxiety and irritability.[symptoma.com] loss, and sleep problems, among other symptoms.[endocrineweb.com]

  • Graves Disease

    It results in various complications including weight loss with catabolism of bone and muscle, cardiac complications and psycho-cognitive complications.[symptoma.com] It can cause irritability, sleeplessness and absence of voluntary muscle movements. Elliot was detected with Graves’ disease in 2008.[healthresearchfunding.org] ˈgrāvz- \ Definition of Graves' disease : a common form of hyperthyroidism that is an autoimmune disease characterized by goiter, rapid and irregular heartbeat, weight loss, irritability[merriam-webster.com]

  • Chronic Kidney Insufficiency

    Nausea, loss of appetite, and vomiting. Urea in the gastric juices may cause upset stomach. This can lead to malnutrition and weight loss.[medical-dictionary.thefreedictionary.com] Treatment can also prevent and manage complications of CKD, such as: fluid overload congestive heart failure anemia brittle bones weight loss electrolyte imbalance Controlling[healthline.com] Symptoms may include: Appetite loss General ill feeling and fatigue Headaches Itching ( pruritus) and dry skin Nausea Weight loss without trying to lose weight Symptoms that[ufhealth.org]

  • Pernicious Anemia

    An elderly black man was admitted to our institution with macrocytic anemia, dysphagia, and significant weight loss.[ncbi.nlm.nih.gov] Long thought hypochondriacal, these findings, plus their time course and her psychopathology (irritability, delusions, hallucinations, with preserved clarity), are all consistent[ncbi.nlm.nih.gov] Some people with pernicious anemia may also become extremely irritable or depressed and, in some rare cases, even experience paranoia (megaloblastic madness).[rarediseases.org]

  • Hypoglycemia

    A 64 year-old African female was brought to the emergency room with a 1-month history of recurrent syncope, weight loss, and abdominal bloating.[ncbi.nlm.nih.gov] An infant presented with short history of jaundice and irritability, examination showed soft hepatomegaly.[ncbi.nlm.nih.gov] loss and hormonal health from an integrative perspective.[healthcentral.com]

  • Obstructive Sleep Apnea

    […] intervention, or CPAP plus a weight-loss intervention for 24 weeks.[nejm.org] Irritability/personality change. Nocturia. Decreased libido.[patient.info] We describe a case series of 4 patients with varying degrees of obstructive sleep apnea who incidentally had a history of nocturnal leg cramps.[ncbi.nlm.nih.gov]

  • Amyotrophic Lateral Sclerosis

    loss in the early stages.[ncbi.nlm.nih.gov] Muscle twitches and cramps are common; they occur because degenerating axons (long fibers extending from nerve-cell bodies) become “irritable.”[web.archive.org] FDA bans quinine for nocturnal leg cramps. Drug Utilization Rev. 1995; Oct:150. 26. Moss AH, Casey P, Stocking CB, Roos RP, Brooks BR, Siegler M.[aafp.org]

  • Insulinoma

    Body mass index (BMI), weight loss (WL) and percentage weight loss (%WL) were main outcomes.[ncbi.nlm.nih.gov] She reported a 30-minute period of fatigue, confusion, poor concentration, irritability, and “staring off” which was noted by parents while the patient was getting ready for[ijpeonline.biomedcentral.com] Weight loss and mental impairment contributed to the diagnosis pitfalls.[ncbi.nlm.nih.gov]

  • Restless Legs Syndrome

    Sign up for our free weekly newsletters and get nutritious recipes, healthy weight-loss tips, easy ways to stayin shape and all the health news you need, delivered straight[besthealthmag.ca] In the older age-onset patients, misdiagnoses also included skin irritation, arthritis, and malingering.[ncbi.nlm.nih.gov] Two common causes of pain or discomfort in legs are nocturnal leg cramps (NLC) and restless leg syndrome (RLS).[doi.org]

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