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94 Possible Causes for islet 1, protein,, zebrafish

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  • LIG4 Syndrome

    Tandem BRCT domains of LigIV mediate a unique mode of protein-protein interaction.[mcb.asm.org] METHODS Zebrafish maintenance, lines and mutagenesis Zebrafish (Danio rerio) were maintained on an Aquatic Habitat system (FL, USA).[zdoc.site] Diabetes Mellitus, Type 1 European Nicotinamide Diabetes Intervention Trial (ENDIT): a randomised controlled trial of intervention before the onset of type 1 diabetes.[brenda-enzymes.org]

  • Vitamin K

    Approximately 60% of protein S in human plasma is bound to the complement regulatory protein C4b-binding protein (C4BP) in a high-affinity, high-molecular-weight complex.[ncbi.nlm.nih.gov] Gavaia and Vincent Laizé , Zebrafish vitamin K epoxide reductases: expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro[doi.org] Synthesis of gamma-carboxy-lated polypeptides by alpha-cells of the pancreatic islets . Biochem Biophys Res Commun 2001; 283: 454-459.[doi.org]

  • Nephrotic Syndrome

    A total of 13/809 proteins were additionally present in the kidney proteome of PeptideAtlas and the Human Protein Atlas, although not in normal human urine and normal human[ncbi.nlm.nih.gov] CRISPR-Cas9 knockout in zebrafish and mice recapitulated the human phenotype of primary microcephaly and resulted in early lethality.[ncbi.nlm.nih.gov] Pancreas/Islet Transplant Program The Pancreas/Islet Transplant Program at the Massachusetts General Hospital Transplant Center provides innovative treatment, transplant and[massgeneral.org]

  • Inflammation

    The rate of protein synthesis in vivo was measured by the incorporation of [3H]phenylalanine into liver proteins in a chronic (5 day) intra-abdominal abscess model.[doi.org] Spaink , Comparative studies of Toll-like receptor signalling using zebrafish , Developmental & Comparative Immunology , 46 , 1 , (35) , (2014) . Bruno A.[doi.org] […] lamina propria CD25 and CD80 cells, enhanced expression of lamina propria cells positive for ligand and receptor molecules α4/β7 and intracellular adhesion molecule (ICAM)-1,[web.archive.org]

  • Cardiac Amyloidosis

    […] of undetermined significance (MGUS) Multiple myeloma A high-protein diet doesn't cause high blood protein.[mayoclinic.org] Human amyloidogenic light chain proteins result in cardiac dysfunction, cell death, and early mortality in zebrafish .[nature.com] Kidney Int. 2002;61:1-9. Jaikaran ET, Clark A. Islet amyloid and type 2 diabetes; from molecular misfolding to islet pathophysiology.[rarediseases.org]

  • Diabetic Nephropathy

    It is reported that low protein diet can improve protein, sugar and lipid metabolism, and reduce the symptoms and complications of renal insufficiency.[ncbi.nlm.nih.gov] The protective role of SRGAP2a in podocyte function also is confirmed in zebrafish, in which knockdown of SRGAP2a, a SRGAP2 ortholog in zebrafish, recapitulates podocyte foot[ncbi.nlm.nih.gov] 38,Suppl.1 1 von: International Congress on Pancreatic and Islet Transplantation: Proceedings of the ...[zdb-katalog.de]

  • Coxsackie Virus

    [bsid125147] PodNet: protein-protein interactions in the podocyte PodNet: protein-protein interactions in the podocyte PodNet is a manually curated network of protein-protein[ncbi.nlm.nih.gov] Pettersson and Arindam Majumdar , The coxsackie and adenovirus receptor (CAR) is required for renal epithelial differentiation within the zebrafish pronephros , Developmental[doi.org] Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes . Diabetes 64 , 1682–1687 (2015). 6.[nature.com]

  • Alstrom Syndrome

    Gov't MeSH terms Abnormalities, Multiple/pathology Aging/metabolism Animals Cilia/genetics Cilia/metabolism* DNA-Binding Proteins/genetics DNA-Binding Proteins/metabolism*[ncbi.nlm.nih.gov] A major contribution to early research has involved using zebrafish, already being studied by heart disease researchers investigating its ability to regenerate its own cardiac[telegraph.co.uk] C-peptide, insulin, islet cells, autoantibodies, growth hormone, insulin-like growth factor (IGF)-1, and insulin-like growth factor binding protein (IGF-BP)-3 measurements[jmg.bmj.com]

  • Alzheimer Disease

    Recently, evidence was reported that γ-secretase activating protein (GSAP, 16 kDa), derived from a larger precursor protein (98 kDa), plays a role in Aβ metabolism through[ncbi.nlm.nih.gov] Zuo, Yu Zhang, Zhiming Gou and Weiying Lin , Novel polysiloxane-based rhodamine B fluorescent probe for selectively detection of Al3 and its application in living-cell and zebrafish[doi.org] Riederer, Gérard Waeber and Amar Abderrahmani , Role of the JNK-interacting protein 1/islet brain 1 in cell degeneration in Alzheimer disease and diabetes , Brain Research[doi.org]

  • Gnathodiaphyseal Dysplasia

    […] showed no significant similarity to any other known protein or protein classes.[ncbi.nlm.nih.gov] […] family and a new African American family), and both missense mutations occur at the cysteine residue at amino acid 356, which is evolutionarily conserved among human, mouse, zebrafish[ncbi.nlm.nih.gov] […] myelogenous leukemia , and intestinal cancer [1] .[wikigenes.org]