Isoelectric EEG: Causes & Reasons

Possible Causes for Isoelectric EEG

An isoelectric EEG is not mandatory, but when used in conjunction with the clinical criteria for brain death, it provides confirmatory evidence of brain death. [clevelandclinic.org]

EEG ( Ad Hoc Committee 1968 ). [medlink.com]

If the EEG is isoelectric or if CBF is absent, the observational period can be shortened. [nature.com]

Coma

The primary mechanism of protection involves a reduction in CMRo2 of up to 55% to 60% at which point the EEG becomes isoelectric. ^ "Barbiturate Coma". Trauma.org. [en.wikipedia.org]

EEG patterns were visually classified as unfavorable (isoelectric, low-voltage, or burst suppression with identical bursts) or favorable (continuous patterns) at 12 and 24 [ncbi.nlm.nih.gov]

A diffusely slowed or normal EEG pattern at 12 hours was associated with good outcome in both montages. [ncbi.nlm.nih.gov]

Hypoglycemic Encephalopathy

Samples of frozen neocortex were used for these measurements., EEG non-isoelectric;, EEG isoelectric for 3 min prior to freezing brain; Δ, (more...) [ncbi.nlm.nih.gov]

As hypoglycemia progresses below 1m M, the EEG becomes isoelectric and neuronal cell death ensues. [ncbi.nlm.nih.gov]

Below 1 m M blood glucose concentrations, brain ATP levels become depleted [ 2 ] ( Fig. 38-2 ), the EEG becomes isoelectric and coma develops. [ncbi.nlm.nih.gov]

Metaphyseal Chondrodysplasia, Spahr Type

The impact was dose-dependent and an isoelectric EEG seemed to be imperative, but fresh research indicated that undiminished burst concealing is not certain inasmuch as neuroprotection [blkhospital.com]

New-Onset Refractory Status Epilepticus

Seizure duration Non-convulsive SE EEG characteristics Isoelectric EEG  poor prognosis (4/4) Burst suppression  poor functional outcome (22/27) Inversely, seizure control [slideplayer.com]

EEG. [46] The optimal extent of burst suppression is not known. [neurologyindia.com]

[…] or an isoelectric EEG recording. [nature.com]

Neuronal Ceroid Lipofuscinosis

Average time to isoelectric EEG (52 months, SD 13) was longer than reported previously (36 months). [ncbi.nlm.nih.gov]

[…] visual-evoked potentials; and G, isoelectric EEG or electroretinogram. [ajnr.org]

INTERPRETATION: Our findings suggest that combination therapy with cysteamine bitartrate and N-acetylcysteine is associated with delay of isoelectric EEG, depletion of GRODs [ncbi.nlm.nih.gov]

Hypoxic-Ischemic Brain Injury

"; and grade 5 ("isoelectric EEG"). [researchgate.net]

EEG with voltage below 20 µV (Grade V). [academic.oup.com]

Specificities for predicting an unfavorable outcome were 100% for isoelectric, discontinuous, or dominant delta activity EEG. [researchgate.net]

Limbic Encephalitis

A 44-year-old woman with impaired consciousness and subsequent coma characterised by an isoelectric EEG was diagnosed with AMPAR-antibody limbic encephalitis. [ncbi.nlm.nih.gov]

The full assortment of electroencephalogram (EEG) and clinical descriptions of the latter are yet to be fully described. [ncbi.nlm.nih.gov]

Severe Neonatal-Onset Encephalopathy with Microcephaly

[…] extensive hypodensities on CT o Treatment of ICP controversial · Prognostic factors: o Severity and duration of encephalopathy – most predictive o Seizures o Brain edema o EEG [emilytam.com]

– isoelectric, suppressed bkgrd, burst-suppression o CT, U/S, MRI o Antenatal factors – low 10 minute Apgar scores · Severe HIE results in microcephaly, MR, seizures, spastic [emilytam.com]

Staphylococcus Aureus Meningitis

EEG TABLE III TRANSFORAMINAL HERNIATION SYNDROME EARLY SIGNS LATE SIGNS PRE-TERMINAL SIGNS � Head tilt, nuchal ridgity, suboccipital tenderness � Respiratory arrest (secondary [atsu.edu]

[…] posturing � Bilaterally dilated and fixed pupils � Loss of vestibulo-ocular reflexes (tested by calorie stimulation or Doll's eye maneuver) � Loss of deep tendon reflexes � Isoelectric [atsu.edu]

Complete Locked-in Syndrome

Everybody who is engaged in determining brain death has noted an isoelectric electroencephalographic (EEG) recording before, as well as electrical brain activity after, the [jamanetwork.com]

Moebius Syndrome

Temporal bone findings in a case of Möbius syndrome are presented. The most striking pathological feature of the case is that the facial nerves ended in the horizontal segment in the temporal bones on both sides. This finding gives direct evidence that the site of nerve lesion in Möbius syndrome is in the[…] [ncbi.nlm.nih.gov]

Bacterial Meningitis

EEG TABLE III TRANSFORAMINAL HERNIATION SYNDROME EARLY SIGNS LATE SIGNS PRE-TERMINAL SIGNS � Head tilt, nuchal ridgity, suboccipital tenderness � Respiratory arrest (secondary [atsu.edu]

Brain Ischemia

If BIS or EEG is available, verify isoelectricity before cessation of circulation. The most important factor during DHCA is operative time (45 to 60 minutes or less). [openanesthesia.org]

Hypothermia due to Anesthesia

However, the temperature at which the EEG becomes isoelectric varies widely between patients—as low as 12.5°C in some studies—and appears to be higher during cooling than [academic.oup.com]

In some centres, the EEG is used to assess the adequacy of cooling before DHCA. [academic.oup.com]

Ocular Toxoplasmosis

EEG TABLE III TRANSFORAMINAL HERNIATION SYNDROME EARLY SIGNS LATE SIGNS PRE-TERMINAL SIGNS � Head tilt, nuchal ridgity, suboccipital tenderness � Respiratory arrest (secondary [atsu.edu]

Fetal Hypoxia

isoelectric line (ISO) featuring in severe cases of fetal hypoxia and acidosis. [ncbi.nlm.nih.gov]

Fetal hypoxia and acidosis were observed to entail some characteristic changes in EEG, that is, a decrease in the frequency and wave amplitude through the appearance of the [ncbi.nlm.nih.gov]

The following changes were found to occur during the development of hypoxia and acidosis:hypoxia, a decrease in the EEG frequency and amplitude, preacidosis with the appearance [ncbi.nlm.nih.gov]

Parenchymatous Cortical Cerebellar Degeneration

The EEG was isoelectric. Cranial ultrasound showed bilateral IVH with ventricular dilation, subdural hemorrhage and a possible vein of Galen aneurysm. [mrineonatalbrain.com]

Status Epilepticus

Not included were patients with open head injury, those whose relatives did not sign the consent form and patients with suspected brain death and an isoelectric EEG. [intechopen.com]

EEG. [46] The optimal extent of burst suppression is not known. [neurologyindia.com]

[…] barbiturate or anesthetic treatment [Table 3] with the drug dosing commonly set in a way in which burst suppression is aimed at interburst intervals of 2–30 s or even an isoelectric [neurologyindia.com]

Hereditary Hyperekplexia

Meanwhile the EEG became isoelectric, and the ECG showed junctional bradycardia, reflecting severe syncope. [doi.org]

Yim-Ebbin Syndrome

EEG as interest of a understanding pro- tection strategy in expectation of or directly following cerebral ischemia, and (3) provocative Wada testing. [nhha.org]

[…] indications: (1) elevated ICP or prominence epilepticus that is refractory to alternative strategies, (2) induction of esoteric worldwide anesthesia with burst ceasing or isoelectric [nhha.org]

Developmental and Epileptic Encephalopathy Type 3

The EEG pattern often shows a suppression-burst pattern with high-voltage bursts of slow waves mixed with multifocal spikes alternating with isoelectric suppression phases [diseaseinfosearch.org]

Reye Syndrome

The EEG at this point is isoelectric. There is almost always a history of a preceding viral illness, especially influenza A or B, or varicella. [web.archive.org]

The EEG at this point is isoelectric. [hawaii.edu]

Neonatal Hypoglycemia

Correlation of density of brain damage with the EEG isoelectric time: a quantitative study. Diabetes 1984;33(11):1090-1098. 5. Siesjo BK. [hawaii.edu]

Beta-Ureidopropionase Deficiency

Pyridoxine trial should be performed in intensive care units because it might be associated with transient isoelectric EEG, which can be associated with respiratory depression [frontiersin.org]

Nesidioblastosis

However, the EEG varied from one of abnormally low amplitude to an isoelectric record. Renal, liver function tests and coagulation profile were normal. [ncbi.nlm.nih.gov]

Bradyarrhythmia

[…] a discontinuous or isoelectric tracing was associated with a poorer neurologic outcome at hospital discharge. [dx.doi.org]

There are no data correlating EEG findings with neurologic outcome after hospital discharge. 2015 Recommendation—New EEGs performed within the first 7 days after pediatric [dx.doi.org]

[…] discontinue life-sustaining therapy). 2015 Evidence Summary Observational data from 2 small pediatric studies 94, 95 showed that a continuous and reactive tracing on an EEG [dx.doi.org]

Sepsis

[…] a discontinuous or isoelectric tracing was associated with a poorer neurologic outcome at hospital discharge. [doi.org]

There are no data correlating EEG findings with neurologic outcome after hospital discharge. 2015 Recommendation—New EEGs performed within the first 7 days after pediatric [doi.org]

[…] discontinue life-sustaining therapy). 2015 Evidence Summary Observational data from 2 small pediatric studies 94, 95 showed that a continuous and reactive tracing on an EEG [doi.org]

Choroid Hemorrhage

The EEG was isoelectric. Cranial ultrasound showed bilateral IVH with ventricular dilation, subdural hemorrhage and a possible vein of Galen aneurysm. [mrineonatalbrain.com]

Cardiomegaly

Isoelectric, burst suppression, seizures • Increase latency in brainstem auditory evoked potential (ABR) and visual evoked potentials (VEP) • Increased cerebral blood flow [slideserve.com]

[…] cortex (occipital), dentate gyrus, hippocampus, caudate nucleus Consequences of Neonatal Hypoglycemia: Clinical Outcome • Symptoms: Irritability, lethargy, seizures, coma • EEG [slideserve.com]