Jaundice: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Jaundice

Cholelithiasis

After "simple" cholecystectomy for lithiasis, biliary disorders can appear, with the onset more than 3 years postoperative, like cholangitis or transitory jaundice. [ncbi.nlm.nih.gov]

Jaundice. Dark coloured stools. Dark coloured urine discharge. Diarrhoea. [practo.com]

But if it gets down to common bile duct than it can also cause obstructive jaundice. Right upper quadrant pain. [youtube.com]

Cholestatic Jaundice

Our report highlights the varied aetiology of obstructive jaundice and the importance of including biliary ascariasis in the differential diagnosis of the jaundiced patient [ncbi.nlm.nih.gov]

Familial acholuric jaundice is another name for the hereditary form of hemolytic jaundice. breast milk jaundice elevated unconjugated bilirubin in some breast-fed infants [medical-dictionary.thefreedictionary.com]

What is Obstructive Jaundice? [healthhype.com]

Infectious Mononucleosis

We report a case of infectious mononucleosis in a 72-year old jaundiced gentleman with ferritin level of 2438 that normalised on clinical improvement. [ncbi.nlm.nih.gov]

[…] patient between 16 and 25 years old who complains of sore throat and fever is more likely to have infectious mononucleosis than another disease; and if - in addition - he is jaundiced [ncbi.nlm.nih.gov]

[…] mononucleosis due to Epstein-Barr virus (EBV) infection sometimes causes acute hepatitis, which is usually self-limiting with mildly elevated transaminases, but rarely with jaundice [ncbi.nlm.nih.gov]

Hemolytic Anemia

The existence of a primary form of acquired hemolytic jaundice has been questioned more and FULL TEXT [annals.org]

The diagnosis of Zieve syndrome was confirmed based on hemolysis and cholestatic jaundice secondary to alcoholic liver disease and heavy drinking. [ncbi.nlm.nih.gov]

Jaundice (yellowing of the skin or eyes) occurs because of the increase in bilirubin. Jaundice may appear or increase at times of illness. [stjude.org]

Choledocholithiasis

[…] colic Charcot’s triad Ascending cholangitis  Suppurative cholangitis Reynold’s pentad Persistent pain, fever, jaundice, shock & AMS  Painful jaundice with dark color [slideshare.net]

Cholangitis, Obstructive Jaundice) How is Common Bile Duct Stone (Choledocholithiasis, Cholangitis, Obstructive Jaundice) Diagnosed? [myvmc.com]

In fact, fluctuating jaundice is so characteristic of choledocholithiasis. [slideshare.net]

Liver Cirrhosis

Differential diagnosis from obstructive jaundice and a severe prognosis without alcohol abstinence make early diagnosis mandatory. [ncbi.nlm.nih.gov]

Jaundice may complicate any stage of cirrhosis. [britannica.com]

The patient also presented with acute encephalopathy, jaundice, right upper quadrant abdominal pain and hyperbilirubinaemia (total bilirubin of 8.1 mg/dL with direct bilirubin [ncbi.nlm.nih.gov]

Hepatitis

Common symptoms include jaundice, nausea, chills, rigors, diaphoresis, fatigue, and abdominal pain. [ncbi.nlm.nih.gov]

[citation needed] Diagnostic tests[24] Function test Pre-hepatic jaundice Jaundice due to the liver Post-hepatic jaundice Total bilirubin Normal / increased Increased Conjugated [en.wikipedia.org]

Hepatic Disorders, Jaundice, and Hepatic Failure Sections: Hepatic Disorders, Jaundice, and Hepatic Failure: Introduction, Epidemiology, Pathophysiology, Clinical Features [web.archive.org]

Portal Cirrhosis

It has a lengthy latent period, usually followed by the sudden appearance of abdominal pain and swelling, hematemesis, dependent edema, or jaundice. [medical-dictionary.thefreedictionary.com]

Besides cirrhosis, the affected person may show jaundice, gastrointestinal bleeding, and kidney failure.Read More [britannica.com]

[…] within the normal range in patients with latent, asymptomatic cirrhosis, 13, 14 whereas it was consistently reduced in patients with portal cirrhosis accompanied by severe jaundice [annals.org]

Alcoholic Liver Disease

The term acute alcoholic cholestasis is suggested for this apparently distinct syndrome of cholestatic jaundice in the absence of hepatitis. [ncbi.nlm.nih.gov]

The diagnosis of Zieve syndrome was confirmed based on hemolysis and cholestatic jaundice secondary to alcoholic liver disease and heavy drinking. [ncbi.nlm.nih.gov]

There is described the case of a 27-year-old patient with jaundice and hepatic encephalopathy with long history of alcohol dependence and substance abuse. [ncbi.nlm.nih.gov]

Biliary Carcinoma

We present the third case of metastatic lung cancer to the common bile duct presenting as abdominal distention and jaundice. [omicsonline.org]

We present a woman diagnosed with metastatic breast cancer in the CBD after presenting with obstructive jaundice. [karger.com]

Jaundice is a common symptom of bile duct cancer. Jaundice causes the skin and the whites of the eyes to turn yellow. [cancer.net]

Cholestasis

The outcomes of patients with cholestatic jaundice depend on the cause. [ncbi.nlm.nih.gov]

Our patient, a 76 year old female, with no past medical history, presented with progressive weakness followed by the onset of jaundice. [omicsonline.org]

A 35 year-old-woman with vitiligo, jaundice and cholestasis fulfilled serological, biochemical and histological criteria for PBC/AIH overlap. [ncbi.nlm.nih.gov]

Bile Duct Stricture

Laboratory reports suggested obstructive jaundice. [ncbi.nlm.nih.gov]

Biloma and jaundice are serious complications associated with bile duct strictures. [ncbi.nlm.nih.gov]

Obstructive jaundice, first evident at 3 weeks of age, became progressively severe. [ncbi.nlm.nih.gov]

Macronodular Cirrhosis

List 3 causes of pre-hepatic jaundice List 2 causes of post-hepatic jaundice. List 3 causes of hepatic jaundice. [quizlet.com]

Pruritus is reported when significant jaundice is present. [medical-dictionary.thefreedictionary.com]

The whites of the eyes and the skin may turn yellow ( jaundice ), and urine may be dark yellow or brown. Stools may be black or bloody. [medical-dictionary.thefreedictionary.com]

Hereditary Spherocytosis

This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist [ncbi.nlm.nih.gov]

In this article the authors present a case of pathological neonatal jaundice resistant to phototherapy in a baby with a family history of Gilbert's syndrome and hereditary [ncbi.nlm.nih.gov]

[…] of hereditary spherocytosis (HS) in a newborn infant is generally made on the basis of a positive family history, spherocytes on blood film and Coombs-negative hemolytic jaundice [ncbi.nlm.nih.gov]

Cholecystitis

The outcomes of patients with cholestatic jaundice depend on the cause. [ncbi.nlm.nih.gov]

A 61-year-old man presented with upper abdominal pain and jaundice. [ncbi.nlm.nih.gov]

[…] patient had right upper quadrant pain with sclera was transferred from emergency room to the hospital, she was proposed to have acute cholecystitis, gallstones, obstructive jaundice [ncbi.nlm.nih.gov]

Acute Cholecystitis

The outcomes of patients with cholestatic jaundice depend on the cause. [ncbi.nlm.nih.gov]

A 61-year-old man presented with upper abdominal pain and jaundice. [ncbi.nlm.nih.gov]

Courvoisier’s Law: The presence of jaundice, palpable gallbladder means that the jaundice is unlikely to be due to stones. [armandoh.org]

Cryptogenic Cirrhosis

Age, jaundice, spiders, palmar erythema and factor V showed a statistically significant difference of the cryptogenic cirrhosis when compared with both alcoholic and viral [ncbi.nlm.nih.gov]

Symptoms of cryptogenic cirrhosis are no different than the symptoms in any other type of cirrhosis: jaundice, abdominal swelling, weight loss, fever and blood in the stool [symptoma.com]

CARDIAC CIRRHOSIS Clinic a l featu r es · Mild jaundice · Liver dysfunction · Hepatomegaly – firm, non tender • *Ascites · Peripheral edema · Oesophageal bleeding · Encephalopathy [medicscientist.com]

Neonatal Jaundice

Background Early jaundice Ix early jaundice Ix late jaundice Management Background Neonatal Jaundice is common in the first week of life (65 % of term infants are clinically [emed.ie]

RESULTS: Physiological jaundice cases showed no significant variations in hematological profile, while jaundice due to ABO incompatibility, septicemia, Rh incompatibility, [ncbi.nlm.nih.gov]

Breast milk jaundice is common. [kidshealthwa.com]

Ascending Cholangitis

The outcomes of patients with cholestatic jaundice depend on the cause. [ncbi.nlm.nih.gov]

Key Clinical Questions What causes jaundice? How are biliary obstruction and cholangitis diagnosed? What are the best imaging modalities? [accessmedicine.mhmedical.com]

Jaundice results from a pathologic process that interferes with the normal metabolism and excretion of bilirubin (Figure 158-1). [accessmedicine.mhmedical.com]

Primary Sclerosing Cholangitis

Jaundice due single ‘dominant strictures’ of the bile duct may present with jaundice and require treatment by endoscopy (ERCP). [royalfree.nhs.uk]

Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of bile ducts..Patients with PSC usually presents with fatigue, jaundice and pruritus. [ncbi.nlm.nih.gov]

As the disease progresses, individuals may develop jaundice (yellowing of skin and darkening of urine). Jaundice is due to the accumulation of bilirubin in the body. [emedicinehealth.com]

Secondary Sclerosing Cholangitis

Cholestatic jaundice as a paraneoplastic feature of secondary sclerosing cholangitis is rare in Hodgkin’s lymphoma. [jamc.ayubmed.edu.pk]

Overall 70% of patients with sclerosing cholangitis had jaundice vs. 25% without sclerosing cholangitis (p CONCLUSIONS: Our results indicate that drugs can lead to bile duct [ncbi.nlm.nih.gov]

A 50 year male presented with acute onset jaundice, significant weight loss and elevated liver enzymes with clinico-radiological suspicion of cholangiocarcinoma. [ncbi.nlm.nih.gov]

Pancreatitis

Detection and diagnosis When making a diagnosis, the doctor checks for signs of jaundice, weakness, emaciation, diarrhea and/or foul-smelling stool. [gwhospital.com]

Detection and Diagnosis When making a diagnosis, the doctor checks for signs of jaundice, weakness, emaciation, diarrhea and/or foul-smelling stool. [aikenregional.com]

ERCP (an endoscopy test) to place a stent in the bile duct to unblock it to relieve jaundice, can trigger acute pancreatitis. [pancreaticcanceraction.org]

Viral Hepatitis

Jaundice is a rare clinical presentation in typhoid fever, therefore hepatitis A should be considered in typhoid fever and jaundice because both enterically transmitted disease [ncbi.nlm.nih.gov]

The dilemma in which an anesthesiologist is put is whether to promise the anesthesia straightaway in the face of a demonstrable acute jaundice in pregnancy to advise a postponement [ncbi.nlm.nih.gov]

Liver Failure

Rare disease associated with jaundice, coagulopathy, and hepatic encephalopathy. [bestpractice.bmj.com]

One of the first signs of a problem with your child’s liver is jaundice. Jaundice happens when the liver is unable to remove bilirubin, a yellow pigment, from the blood. [seattlechildrens.org]

The insult should be a hepatic one and presentation in the form of liver failure (jaundice, encephalopathy, coagulopathy, ascites) with or without extrahepatic organ failure [ncbi.nlm.nih.gov]

Pancreatic Adenocarcinoma

The main symptoms include fatigue, weight loss, abdominal pain, and jaundice. [symptoma.com]

Distal cholangiocarcinoma Usually presents with obstructive jaundice, bile duct dilation. [clinicaladvisor.com]

A 70-year-old Caucasian male presented with vague complaints of nausea, vomiting and abdominal distention, with subsequent development of jaundice. [ncbi.nlm.nih.gov]

Malignant Neoplasm of the Pancreas

Jaundice and related symptoms Jaundice is yellowing of the eyes and skin. [cancer.org]

In patients with inoperable lesions and jaundice, endoscopic placement of a bile duct stent relieves jaundice. Duodenal stenting is frequently done. [msdmanuals.com]

This can also cause jaundice. [cancer.org]

Drug-Induced Toxic Hepatitis

Combination of estrogenic and progestational steroids; estrogen is primarily responsible Intrahepatic cholestasis Pruritus and jaundice Susceptible patients: idiopathic jaundice [slideshare.net]

Anorexia, nausea, and vomiting are the usual symptoms; jaundice and hepatomegaly are noted on physical assessment. [hepatitiscentral.com]

Neoplastic obstruction of the bile ducts can also cause jaundice, although pain is frequently absent. [nature.com]

Toxic Liver Disease

In addition to the elevation of ALT and AST levels, cases of liver necrosis, jaundice, and fulminant hepatitis with and without jaundice have occurred. [emedicine.medscape.com]

Others may have Loss of appetite Nausea and vomiting Diarrhea Dark-colored urine and pale bowel movements Stomach pain Jaundice, yellowing of skin and eyes Some forms of hepatitis [icdlist.com]

Jaundice may then follow. Most patients with isoniazid hepatitis recover fully and promptly after stopping the drug. [medicinenet.com]

Isoniazid Hepatitis

However, jaundice was notably absent in the patients with enzyme elevations and prompted a further investigation into the possible effect of INH on bilirubin metabolism. [ncbi.nlm.nih.gov]

A prodromal period characterized by fatigue, weakness, anorexia, and malaise was noted in all patients before the appearance of jaundice. [annals.org]

ALTHOUGH isoniazid (INH) is thought to be a rare cause of jaundice its precise role is unclear. [nejm.org]

Acute Fatty Liver of Pregnancy

Jaundice, fever, abdominal pain, anorexia, and nausea are some of the main complaints, whereas liver failure and coagulopathy can lead to both maternal and fetal death in [symptoma.com]

A review of this disorder and other medical emergencies causing jaundice in pregnancy is presented. [ncbi.nlm.nih.gov]