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598 Possible Causes for Jaundice, Knee Pain, Pallor

  • Paroxysmal Nocturnal Hemoglobinuria

    Although the severe obstructive jaundice requiring endoscopic therapy following cholecystectomy was complicated, critical intravascular hemolysis and thrombosis were not observed[ncbi.nlm.nih.gov] […] disorder with insidious onset (usually in the third or fourth decade) and chronic course, characterized by episodes of hemolytic anemia, hemoglobinuria (chiefly at night), pallor[medical-dictionary.thefreedictionary.com] Study Persistent Pain After Total Knee Replacement Study Rotator Cuff Stem Cell Clinical Trial Treatment Study for Articular Cartilage Injuries in the Knee Pain Management[rush.edu]

  • Sickle Cell Disease

    Jaundice, or yellowing of the skin, eyes, and mouth. Jaundice is a common sign and symptom of sickle disease.[hopkinsmedicine.org] […] swelling of the hands and feet (dactylitis), pneumococcal sepsis or meningitis, severe anemia and acute splenic enlargement (splenic sequestration), acute chest syndrome, pallor[pediatrics.aappublications.org] Hip or knee pain should prompt consideration of avascular necrosis.[clinicaladvisor.com]

  • Growth Hormone Deficiency

    The proband is a 5-year-old girl who presented with neonatal hypoglycaemia and prolonged jaundice.[ncbi.nlm.nih.gov] Clinical and laboratory investigations showed pallor, hepatosplenomegaly, anemia and low/normal platelet count.[ncbi.nlm.nih.gov] This may be a sign of increased pressure in the brain Any allergic reaction you experience to the injection of Nutropin therapy A limp or have hip or knee pain A fracture[nutropin.com]

  • Multiple Myeloma

    Three years later, she showed massive ascites and jaundice.[ncbi.nlm.nih.gov] A physical examination revealed generalized pallor and dehydration but no signs of abdominal peritoneal irritation.[ncbi.nlm.nih.gov] As a result, affected individuals may have a reduced number of red blood cells ( anemia ), which can cause fatigue, weakness, and unusually pale skin (pallor); a low number[ghr.nlm.nih.gov]

  • Hemophilia

    Most people can safely return to work after the jaundice clears, even if their liver function test results aren’t quite normal.[arizonahemophilia.org] […] uncles Symptoms recurrent or severe bleeding bleeding in unusual places (e.g. joints) mucocutaneous bleeding (e.g. gums, nose, easy bruising) Physical Examination inspection pallor[orthobullets.com] You also may bleed into your knees, ankles, and elbows. Bleeding in the joints causes pain and, if not treated, can lead to arthritis.[medlineplus.gov]

  • Gaucher Disease

    Investigations General assessment FBC and differential (assess the degree of pancytopenia); LFTs (minor elevations of liver enzymes are common but jaundice is a poor prognostic[patient.info] Growth retardation in children Pain and degeneration of joints and bone-covering tissue Loss of bone density leading to widening of bones along the knee joint curvature of[gaucherdisease.org.uk] The gastrointestinal features include hepatosplenomegaly, jaundice , hepatic (liver) failure, and ascites (fluid in the abdomen).[medicinenet.com]

  • Rheumatoid Arthritis

    The symptoms improved temporarily, but five months later, the fever, skin rash, jaundice, and thrombocytopenia relapsed.[ncbi.nlm.nih.gov] Symptoms include weakness, low energy, pallor, and shortness of breath.[emedicinehealth.com] Knee and hip replacements are most common. The effects of surgery can help to ease pain and regain joint movement.[familydoctor.org]

  • Kawasaki Disease

    We describe here two cases presented with fever, and acute jaundice as initial features of Kawasaki disease.[ncbi.nlm.nih.gov] Pallor of the proximal parts of the fingernails and/or toenails may appear within 7 days after the start of Kawasaki Disease.[physio-pedia.com] (other than neonatal jaundice).[clinicaltrials.gov]

  • Juvenile Rheumatoid Arthritis

    A 29-yr-old male was admitted with high fever and jaundice for one month. He was diagnosed as juvenile arthritis 16 yr ago.[ncbi.nlm.nih.gov] Majority presented with fever, pallor, arthritis, night pain, and bone pain.[ncbi.nlm.nih.gov] Each session the patient was asked to rate his pain using the Faces Pain Scale.[ncbi.nlm.nih.gov]

  • Granulomatosis with Polyangiitis

    All other causes of cholestatic jaundice were ruled out.[ncbi.nlm.nih.gov] […] quiet OU Iris : Normal architecture OU Lens: Trace nuclear sclerosis, cortical cataracts OU Vitreous : Normal OU Dilated fundus examination: (Figure 2) Disc : Mild temporal pallor[webeye.ophth.uiowa.edu] Joint pain also is a symptom of Wegener's granulomatosis. Pain within the joint is a common cause of shoulder pain, ankle pain, and knee pain.[medicinenet.com]

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