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341 Possible Causes for Jaundice, Lactate Dehydrogenase Increased, Mild Anemia

  • Thalassemia

    Diagnostic methods Diagnosis is suspected in infants younger than 2 years of age with severe microcytic anemia, mild jaundice and hepatosplenomegaly.[orpha.net] At the end of the treatment period, Hb and HbF increased by 2.5   1.8 g/dL and 2.5   1.6 g/dL, while bilirubin, lactate dehydrogenase, and the nucleated red blood cell count[ncbi.nlm.nih.gov] Mild anemia can make you feel tired. Mild anemia caused by alpha thalassemia trait might be mistaken for iron-deficiency anemia.[web.archive.org]

  • Hereditary Spherocytosis

    This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist[ncbi.nlm.nih.gov] Reticulocytosis, increased bilirubin, increased lactate dehydrogenase, increased urinary and fecal urobilinogen, and decreased haptoglobin, reflect increased erythrocyte production[clinicaladvisor.com] A 27-year-old Nigerian woman presented with mild anemia, jaundice, splenomegaly and a history of multiple blood transfusion.[ncbi.nlm.nih.gov]

  • Cooley's Anemia

    Children develop life-threatening anemia, have failure to thrive, and may develop jaundice.[secure.ssa.gov] […] and a decreasing trend in the serum lactate dehydrogenase (LDH) and serum unconjugated bilirubin levels.[onlinelibrary.wiley.com] People with Cooley's anemia make less hemoglobin and fewer circulating red blood cells than normal, which results in mild or severe anemia.[blood.emedtv.com]

  • Hemoglobin C Disease

    In some cases, jaundice may occur. Some people may develop gallstones that need to be treated. In most cases, no treatment is needed.[nlm.nih.gov] Hemoglobin C disease is a hemoglobinopathy causing mild hemolytic anemia.[symptoma.com] There may be intermittent abdominal discomfort, splenomegaly, and slight jaundice.[connects.catalyst.harvard.edu]

  • Hereditary Elliptocytosis

    As neonates, the nine relatives did not have any significant jaundice or anemia that was recognizable.[ncbi.nlm.nih.gov] Diagnostic tests Key laboratory studies comprise a complete blood count (CBC), reticulocyte count, bilirubin, haptoglobin, lactate dehydrogenase (LDH), Coombs test, potassium[symptoma.com] The patient presented for a general check up when his CBC showed only mild anemia with slightly increased reticulocytes.[ncbi.nlm.nih.gov]

  • Toxic Hemolytic Anemia

    Two months later he was referred to the Emergency Room due to worsening of his general health, floating in the right hip and mucocutaneous jaundice.[unboundmedicine.com] DISCUSSION The initial symptoms and laboratory findings of hemolytic anemia, depressed hemoglobin and haptoglobin concentrations, increased lactate dehydrogenase, increased[clinchem.aaccjnls.org] anemia and are more likely to have spontaneous remissions of the disease with resolution in 6 months, thus intervention may be minimal or unnecessary in these groups.[pedclerk.bsd.uchicago.edu]

  • Infectious Mononucleosis

    We report a case of infectious mononucleosis in a 72-year old jaundiced gentleman with ferritin level of 2438 that normalised on clinical improvement.[ncbi.nlm.nih.gov] anemia, neutropenia, and thrombocytopenia BSR CRP Transaminases Note: Pfeiffer’s gland cells are characterized by a basophilic vacuole in the cytoplasm and eccentrically[lecturio.com] Jaundice. A yellowing of your skin and the whites of your eyes (jaundice) also occurs occasionally.[mayoclinic.com]

  • Autoimmune Hemolytic Anemia

    Secondary AIHA might not be diagnosed appropriately because the obstructive jaundice observed in type 1 AIP/IgG4-SC can obscure the presence of hemolytic jaundice.[ncbi.nlm.nih.gov] Unconjugated bilirubin is usually, but not always, elevated and urine urobilinogen is increased. Lactate dehydrogenase is usually elevated into the thousands.[clinlabnavigator.com] anemia and are more likely to have spontaneous remissions of the disease with resolution in 6 months, thus intervention may be minimal or unnecessary in these groups.[pedclerk.bsd.uchicago.edu]

  • Microangiopathic Hemolytic Anemia

    A newborn infant with a large hepatic hemangioma developed congestive heart failure, consumption coagulopathy, microangiopathic hemolytic anemia, and obstructive jaundice.[ncbi.nlm.nih.gov] Laboratory abnormalities Anemia Increased lactate dehydrogenase. Increased indirect bilirubin. Decreased haptoglobin. Increased urine urobilinogen.[clinicaladvisor.com] Indirect evidence of hemolysis was suggested by mild anemia, elevation of serum lactate dehydrogenase, and examination of the patient's bone marrow.[ncbi.nlm.nih.gov]

  • Hemolytic Anemia

    The existence of a primary form of acquired hemolytic jaundice has been questioned more and FULL TEXT[annals.org] Hemolysis was confirmed by a complete drop in haptoglobin, hemopexin and increased plasma lactate dehydrogenase, an increased red blood cell distribution width and osmotic[ncbi.nlm.nih.gov] All the children presented with neonatal hemolytic anemia. Beyond the neonatal period, they did not have jaundice or hemolysis, but continued to have mild anemia.[ncbi.nlm.nih.gov]

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