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901 Possible Causes for Jaundice, Leg Ulcer

  • Malignant Neoplasm

    […] spread to other parts of the body then the following symptoms may be experienced by the individual: Low back pain or pain in the pelvis to bone metastasis Abdominal pain and jaundice[epainassist.com]

  • Tuberculosis

    A 50 year male presented with acute onset jaundice, significant weight loss and elevated liver enzymes with clinico-radiological suspicion of cholangiocarcinoma.[ncbi.nlm.nih.gov] Skin - TB can cause certain rashes, including erythema nodosum - a red, lumpy rash on the legs - or lupus vulgaris which gives lumps or ulcers.[patient.info] Tell your doctor or health care worker if you have unexplained illness or any of the following symptoms happen: nausea and/or vomiting jaundice - yellow skin or eyes, dark[nt.gov.au]

  • Hereditary Spherocytosis

    This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist[ncbi.nlm.nih.gov] However, complete clearance of the leg ulcer was not achieved until two months after a splenectomy.[ncbi.nlm.nih.gov] Taylor (1939) reported a case of chronic leg ulcer in HS. [4] In our case both the patient's and his mother's main problem was recurrent leg ulceration, that too started at[ijdvl.com]

  • Pyruvate Kinase Deficiency

    Pyruvate kinase deficiency may cause pregnancy-associated jaundice.[ncbi.nlm.nih.gov] A splenectomy was performed and the leg ulcer was treated un-successfully with a pinch graft.[ncbi.nlm.nih.gov] Adults may have chronic leg ulcers. Differential diagnosis Other causes of haemolytic anaemia .[patient.info]

  • Sickle Cell Disease

    Jaundice, or yellowing of the skin, eyes, and mouth. Jaundice is a common sign and symptom of sickle disease.[hopkinsmedicine.org] The third patient had sickle cell trait with an extensive leg ulcer that was associated with epidermoid carcinoma.[ncbi.nlm.nih.gov] People always have anemia and sometimes jaundice.[merckmanuals.com]

  • Cooley's Anemia

    Children develop life-threatening anemia, have failure to thrive, and may develop jaundice.[secure.ssa.gov] Patients may have splenomegaly and bone deformities, recurrent leg ulcers, gallstones and infections.[myvmc.com] Common symptoms include pallor, jaundice, leg ulcers, gallstones (cholelithiasis), and abnormal enlargement of the liver and spleen.[rarediseases.org]

  • Cholestasis

    A 35 year-old-woman with vitiligo, jaundice and cholestasis fulfilled serological, biochemical and histological criteria for PBC/AIH overlap.[ncbi.nlm.nih.gov] A 37-year-old man was admitted to our hospital for nephrotic syndrome and a trophic ulcer in the left leg.[care.diabetesjournals.org] Our patient, a 76 year old female, with no past medical history, presented with progressive weakness followed by the onset of jaundice.[omicsonline.org]

  • Alpha-1 Antitrypsin Deficiency

    Infants who develop jaundice secondary to alpha-1 antitrypsin deficiency usually have resolution of the jaundice within the first year of life.[rileychildrens.org] The first was a 24-year-old woman with known AATD who presented with painful leg ulcers refractory to treatment with corticosteroids and colchicine.[ncbi.nlm.nih.gov] Nodules may be widespread over the legs, arms, trunk or face. The nodules may ulcerate, bleed and leak oily material. The patient may be febrile .[dermnetnz.org]

  • Thalassemia

    Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[orpha.net] The latter are linked to a high prevalence of thromboembolic and cerebrovascular events, as well as leg ulcers and pulmonary hypertension.[ncbi.nlm.nih.gov] Diagnostic methods Diagnosis is suspected in infants younger than 2 years of age with severe microcytic anemia, mild jaundice and hepatosplenomegaly.[orpha.net]

  • Anabolic Steroid

    These cases are reported because each was severely jaundiced (peak bilirubin level 62 mg/dl), developed advanced hepatic failure (Child's Class B) and was referred to a liver[ncbi.nlm.nih.gov] A total of 44 patients with LDS and venous ulcers were enrolled and treated with either leg compression alone (placebo) or leg compression plus oral stanozolol 2 mg twice[ncbi.nlm.nih.gov] When used in therapeutic doses, these drugs produce clinical jaundice in just a small number of recipients.[ncbi.nlm.nih.gov]

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