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901 Possible Causes for Jaundice, Leg Ulcer

  • Malignant Neoplasm

    […] spread to other parts of the body then the following symptoms may be experienced by the individual: Low back pain or pain in the pelvis to bone metastasis Abdominal pain and jaundice[]

  • Tuberculosis

    A 50 year male presented with acute onset jaundice, significant weight loss and elevated liver enzymes with clinico-radiological suspicion of cholangiocarcinoma.[] Skin - TB can cause certain rashes, including erythema nodosum - a red, lumpy rash on the legs - or lupus vulgaris which gives lumps or ulcers.[] Tell your doctor or health care worker if you have unexplained illness or any of the following symptoms happen: nausea and/or vomiting jaundice - yellow skin or eyes, dark[]

  • Hereditary Spherocytosis

    This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist[] However, complete clearance of the leg ulcer was not achieved until two months after a splenectomy.[] Taylor (1939) reported a case of chronic leg ulcer in HS. [4] In our case both the patient's and his mother's main problem was recurrent leg ulceration, that too started at[]

  • Pyruvate Kinase Deficiency

    Pyruvate kinase deficiency may cause pregnancy-associated jaundice.[] A splenectomy was performed and the leg ulcer was treated un-successfully with a pinch graft.[] Adults may have chronic leg ulcers. Differential diagnosis Other causes of haemolytic anaemia .[]

  • Sickle Cell Disease

    Jaundice, or yellowing of the skin, eyes, and mouth. Jaundice is a common sign and symptom of sickle disease.[] The third patient had sickle cell trait with an extensive leg ulcer that was associated with epidermoid carcinoma.[] People always have anemia and sometimes jaundice.[]

  • Cooley's Anemia

    Children develop life-threatening anemia, have failure to thrive, and may develop jaundice.[] Patients may have splenomegaly and bone deformities, recurrent leg ulcers, gallstones and infections.[] Common symptoms include pallor, jaundice, leg ulcers, gallstones (cholelithiasis), and abnormal enlargement of the liver and spleen.[]

  • Cholestasis

    A 35 year-old-woman with vitiligo, jaundice and cholestasis fulfilled serological, biochemical and histological criteria for PBC/AIH overlap.[] A 37-year-old man was admitted to our hospital for nephrotic syndrome and a trophic ulcer in the left leg.[] Our patient, a 76 year old female, with no past medical history, presented with progressive weakness followed by the onset of jaundice.[]

  • Alpha-1 Antitrypsin Deficiency

    Infants who develop jaundice secondary to alpha-1 antitrypsin deficiency usually have resolution of the jaundice within the first year of life.[] The first was a 24-year-old woman with known AATD who presented with painful leg ulcers refractory to treatment with corticosteroids and colchicine.[] Nodules may be widespread over the legs, arms, trunk or face. The nodules may ulcerate, bleed and leak oily material. The patient may be febrile .[]

  • Thalassemia

    Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[] The latter are linked to a high prevalence of thromboembolic and cerebrovascular events, as well as leg ulcers and pulmonary hypertension.[] Diagnostic methods Diagnosis is suspected in infants younger than 2 years of age with severe microcytic anemia, mild jaundice and hepatosplenomegaly.[]

  • Anabolic Steroid

    These cases are reported because each was severely jaundiced (peak bilirubin level 62 mg/dl), developed advanced hepatic failure (Child's Class B) and was referred to a liver[] A total of 44 patients with LDS and venous ulcers were enrolled and treated with either leg compression alone (placebo) or leg compression plus oral stanozolol 2 mg twice[] When used in therapeutic doses, these drugs produce clinical jaundice in just a small number of recipients.[]

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