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511 Possible Causes for Jaundice, Leukopenia, Pancytopenia

  • Pernicious Anemia

    She was readmitted with jaundice and macrocytic anemia.[ncbi.nlm.nih.gov] A deficiency of white blood cells ( leukopenia ) and platelets ( thrombocytopenia ) in the blood may occur.[britannica.com] The outcome was rapidly marked by febrile pancytopenia and ataxia leading to the diagnosis of pernicious anemia.[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    Although the severe obstructive jaundice requiring endoscopic therapy following cholecystectomy was complicated, critical intravascular hemolysis and thrombosis were not observed[ncbi.nlm.nih.gov] CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov] We report a 19-year-old female patient admitted to the hospital with pancytopenia. Workout of pancytopenia disclosed paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov]

  • Severe Aplastic Anemia

    Symptoms include fatigue, pale skin, fast heartbeat (tachycardia), trouble breathing, chills, backache, and yellow skin ( jaundice ).[webmd.com] Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia (infections).[msdmanuals.com] Abstract Severe aplastic anemia (SAA) is an autoimmune disease characterized by severe pancytopenia and bone marrow failure.[ncbi.nlm.nih.gov]

  • T-cell Acute Lymphoblastic Leukemia

    Obstructive jaundice: an unusual initial manifestation of intra-abdominal non-Hodgkin lymphoma in a child.[journals.lww.com] Most frequently reported AEs included somnolence and nausea in adult patients and leukopenia and lymphocytopenia in pediatric patients.[ci.nii.ac.jp] The patient was a 16-year-old boy who presented with septic shock and pancytopenia, likely precipitated by an acute parvovirus B19 infection.[ncbi.nlm.nih.gov]

  • Acute Arsenic Poisoning

    Manifestations are suggestive of a general toxic state with alterations of consciousness, from confusion until delirium, crash, hematuria, jaundice and renal insufficiency[pathopedia-india.com] ) and easy bruising / petechia (thrombocytopenia) Anemia and leukopenia are common in chronic arsenic toxicity, are often accompanied by thrombocytopenia and mild eosinophilia[pathologyoutlines.com] AAP can lead to several hematological ailments that are exemplified by bone marrow suppression leading to normocytic anemia or pancytopenia, disseminated intravascular coagulation[symptoma.com]

  • Multicentric Castleman's Disease

    Jaundice may be noted. Additional complaints consistent with MCD are xerostomia, rash and neurological deficits.[symptoma.com] Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present.[ncbi.nlm.nih.gov] Abstract An HIV positive black African woman presented with widespread lymphadenopathy and pancytopenia that had been ascribed to tuberculosis.[ncbi.nlm.nih.gov]

  • Infectious Mononucleosis

    We report a case of infectious mononucleosis in a 72-year old jaundiced gentleman with ferritin level of 2438 that normalised on clinical improvement.[ncbi.nlm.nih.gov] Leukopenia and thrombocytopenia are not uncommon.[ncbi.nlm.nih.gov] […] infection as an adult is a risk factor for the development of multiple sclerosis. [1, 2] Hematologic complications can include development of autoimmune hemolytic anemia, pancytopenia[emedicine.medscape.com]

  • Graft-versus-Host-Disease

    We report the case of a 37-year-old man with a previous bone marrow transplantation presenting with abdominal pain, diarrhoea and jaundice.[ncbi.nlm.nih.gov] The clinical entity characterized by anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the graft vs host[icd10data.com] All cases had diarrhea and pancytopenia, 4 out of 5 presented with erythematous skin rashes, and 2 had cytomegalovirus colitis.[ncbi.nlm.nih.gov]

  • Niemann-Pick Disease

    Although neurodegeneration defines the disease's severity, in most patients it is preceded by hepatic complications such as cholestatic jaundice or hepatomegaly.[ncbi.nlm.nih.gov] Patients with type B NPD have minimal neurologic involvement but pancytopenia is common.[symptoma.com] RESULTS: Four patients were admitted at the age of 1-10 months due to jaundice, hepatosplenomegaly and psychomotor retardation.[ncbi.nlm.nih.gov]

  • Aplastic Anemia

    When clinical manifestations appear, these include choluria, jaundice, and abdominal pain.[ncbi.nlm.nih.gov] Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia (infections).[merckmanuals.com] Differentiation of AN-associated pancytopenia from other types of pancytopenia, especially idiopathic aplastic anemia (IAA), has not been studied.[ncbi.nlm.nih.gov]

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