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145 Possible Causes for Jaundice, Pallor, Peripheral Blood Smear Abnormal

  • Thalassemia

    Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[orpha.net] […] beta chain that results in microcytic hypochromic anemia, an abnormal peripheral blood smear with nucleated red blood cells, and reduced amounts of hemoglobin A.[meddean.luc.edu] Clinical description Onset is during infancy with severe anemia, failure to thrive and progressive pallor.[orpha.net]

  • Severe Aplastic Anemia

    Symptoms include fatigue, pale skin, fast heartbeat (tachycardia), trouble breathing, chills, backache, and yellow skin ( jaundice ).[webmd.com] A complete blood count and reticulocyte count usually show depression of all blood elements (pancytopenia). The peripheral blood smear shows no abnormal cells.[med.uth.edu] There is usually a waxy pallor, and hemorrhages occur in the mucous membranes, skin, and other organs.[britannica.com]

  • T-cell Acute Lymphoblastic Leukemia

    Obstructive jaundice: an unusual initial manifestation of intra-abdominal non-Hodgkin lymphoma in a child.[journals.lww.com] There was moderate pallor, bilateral, multiple, discrete, soft cervical lymph nodes with largest measuring up to 2 cm.[henrypublishinggroups.com] […] present with signs of bone marrow failure, such as anemia, neutropenia and thrombocytopenia, manifesting as recurrent and possibly life-threatening infections, fatigue, fever, pallor[symptoma.com]

  • Hereditary Spherocytosis

    This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist[ncbi.nlm.nih.gov] blood smear, hyperbilirubinemia, and abnormal results on the osmotic fragility test.[steadyhealth.com] Incidentally, the parents provided a history of repeated episodes of pallor and jaundice since she was two and half years old.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Secondary AIHA might not be diagnosed appropriately because the obstructive jaundice observed in type 1 AIP/IgG4-SC can obscure the presence of hemolytic jaundice.[ncbi.nlm.nih.gov] Microangiopathic changes on the peripheral blood smear are far more prominent in DIC than the mere presence of spherocytes as seen in AIHA.[oncologynurseadvisor.com] A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov]

  • Cooley's Anemia

    Children develop life-threatening anemia, have failure to thrive, and may develop jaundice.[secure.ssa.gov] Blood tests Peripheral blood smear shows small, abnormally-shaped red blood cells Complete blood count shows anemia Haemoglobin electrophoresis shows abnormal hemoglobin Prognosis[myvmc.com] The anemia surfaces in the first few months after birth and becomes progressively more severe leading to pallor and easy fatigability, failure to thrive (grow), bouts of fever[medicinenet.com]

  • Chronic Lymphocytic Leukemia

    Swelling and a yellow pigment of the skin (jaundice) may also occur. The National Cancer Institute has published a six-step description of the staging of this disorder.[rarediseases.org] Peripheral blood smear revealed leukocytosis with absolute lymphocytosis (absolute lymphocyte count: 37870 cells/mm³).[ncbi.nlm.nih.gov] We describe a case of a 77-year-old man who presented with fatigue, pallor and lower limb pain and weakness.[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    Jaundice, or yellowing of the skin, eyes, and mouth. Jaundice is a common sign and symptom of sickle disease.[hopkinsmedicine.org] smear (also called peripheral smear and manual differential) to screen for abnormal-looking and sickle-shaped RBCs Iron studies to evaluate the body's level of iron, which[labtestsonline.org] ASS: Inquire about noticeable increase in weakness or pallor, syncope, and sudden abdominal distention.[web.archive.org]

  • Hemolytic Uremic Syndrome

    A week later, he presents to the ER with jaundice, abdominal pain, and easy bruising. Lab results come back with low platelet count, anemia, and increased creatinine.[step2.medbullets.com] These abnormal findings may include: Hemolytic anemia: the red blood cell count is low and a peripheral blood smear, in which blood is examined under a microscope, will show[medicinenet.com] However, eight days post delivery, the patient developed severe nausea and vomiting followed by hematuria, spontaneous bruising, marked pallor, icteric sclera, and lethargy[ncbi.nlm.nih.gov]

  • Microangiopathic Hemolytic Anemia

    A newborn infant with a large hepatic hemangioma developed congestive heart failure, consumption coagulopathy, microangiopathic hemolytic anemia, and obstructive jaundice.[ncbi.nlm.nih.gov] With these findings, a peripheral blood smear examination should be performed, which will reveal the presence of schistocytes.[symptoma.com] -sudden pallor -black urine then oliguria (low urine output) then anuria How do you diagnose hemolytic uremia syndrome?[quizlet.com]

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