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179 Possible Causes for Jaundice, Pallor, Peripheral Blood Smear Abnormal

  • Thalassemia

    Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[] […] beta chain that results in microcytic hypochromic anemia, an abnormal peripheral blood smear with nucleated red blood cells, and reduced amounts of hemoglobin A.[] Clinical description Onset is during infancy with severe anemia, failure to thrive and progressive pallor.[]

  • T-cell Acute Lymphoblastic Leukemia

    Obstructive jaundice: an unusual initial manifestation of intra-abdominal non-Hodgkin lymphoma in a child.[] There was moderate pallor, bilateral, multiple, discrete, soft cervical lymph nodes with largest measuring up to 2 cm.[] […] present with signs of bone marrow failure, such as anemia, neutropenia and thrombocytopenia, manifesting as recurrent and possibly life-threatening infections, fatigue, fever, pallor[]

  • Chronic Lymphocytic Leukemia

    Swelling and a yellow pigment of the skin (jaundice) may also occur. The National Cancer Institute has published a six-step description of the staging of this disorder.[] Peripheral blood smear revealed leukocytosis with absolute lymphocytosis (absolute lymphocyte count: 37870 cells/mm³).[] We describe a case of a 77-year-old man who presented with fatigue, pallor and lower limb pain and weakness.[]

  • Severe Aplastic Anemia

    Tell your health care provider right away if you have any of these signs and symptoms of liver problems: yellowing of the skin or the whites of the eyes (jaundice) unusual[] A complete blood count and reticulocyte count usually show depression of all blood elements (pancytopenia). The peripheral blood smear shows no abnormal cells.[] There is usually a waxy pallor, and hemorrhages occur in the mucous membranes, skin, and other organs.[]

  • Sickle Cell Crisis

    Experience hemolytic jaundice. D. Have chronic anemia. 4.[] It is associated with pentard of signs and symptoms: thrombocytopenia, microangiopathic hemolytic anemia (schistocytes on peripheral blood smear), neurological abnormalities[] Pallor. First aid treatment for a sickle cell crisis Provide reassurance Contact medical help - the patient may know the details of who to contact during a crisis.[]

  • Babesiosis

    Jaundice, hepatosplenomegaly, anemia and conjugated hyperbilirubinemia developed in this preterm infant.[] After an uncomplicated repeat caesarean delivery of a healthy newborn, infection with Babesia species was diagnosed incidentally on a peripheral blood smear.[] Physical examination may reveal fever, splenomegaly, hepatomegaly, and pallor or jaundice. The diagnosis is confirmed with laboratory testing (see below).[]

  • Arsenic Poisoning

    Skin discoloration – darkening (hyperpigmentation), pale ( pallor ), yellow (jaundice), blue (cyanosis). Mee’s lines – white lines on fingernails and/or toenails.[] Both patients had coarsely stippled red blood cells with markedly abnormal nuclei in their peripheral blood smears.[] Jaundice, hepatomegaly, pancreatitis. Neurological: CNS depression, encephalopathy and coma. Seizures. Haematological: Acute haemolysis. Bone marrow suppression.[]

  • Cooley's Anemia

    Children develop life-threatening anemia, have failure to thrive, and may develop jaundice.[] Blood tests Peripheral blood smear shows small, abnormally-shaped red blood cells Complete blood count shows anemia Haemoglobin electrophoresis shows abnormal hemoglobin Prognosis[] The anemia surfaces in the first few months after birth and becomes progressively more severe leading to pallor and easy fatigability, failure to thrive (grow), bouts of fever[]

  • Megaloblastic Anemia

    (specifically) Loss of gastric acid, dercreased intrinsic fator (needed for b12 absorbtion,GI disturbances S&S of Magaloblastic anemia Common manifestations of anemia , jaundice[] General examination showed severe pallor. On systemic examination, no abnormality was detected, confirmed by ultrasonography abdomen.[] Inclusion criteria for the study were; age 9 to 36 months, refusal of food except for breast and cow milk, loss of appetite, developmental delay, significant pallor, and hypersegmentation[]

  • Hereditary Spherocytosis

    This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist[] blood smear, hyperbilirubinemia, and abnormal results on the osmotic fragility test.[] Incidentally, the parents provided a history of repeated episodes of pallor and jaundice since she was two and half years old.[]

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