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22 Possible Causes for Jaundice, Pancytopenia, Polyclonal Hyperglobulinemia

  • Multicentric Castleman's Disease

    Jaundice may be noted. Additional complaints consistent with MCD are xerostomia, rash and neurological deficits.[symptoma.com] Diffuse lymph-node enlargement, splenomegaly and pancytopenia were detected. Induction with Rituximab was made because pancytopenia was present.[ncbi.nlm.nih.gov] hyperglobulinemia, elevated transaminases and renal disease. 2 , 5 , 7 Dispenzieri et al. 8 analyzed the clinical spectrum of Castleman’s disease in 113 patients.[pagepress.org]

  • Chronic Active Hepatitis B

    The symptoms of liver cancer include weight loss, loss of appetite, nausea and vomiting, and jaundice.[news-medical.net] A 28-year-old man was admitted to our department with intermittent fever, hepatosplenomegaly and pancytopenia.[ncbi.nlm.nih.gov] hyperglobulinemia.[hepatitiscentral.com]

  • Primary Myelofibrosis

    Seek medical care right away for uncontrolled bleeding, shortness of breath, or jaundice (yellow skin and whites of the eyes) that gets worse.[nlm.nih.gov] This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[aoporphan.com] Polyclonal hyperglobulinemia may be present. Patients with sporadic idiopathic or familial pulmonary hypertension have significant marrow fibrosis.[patient-help.com]

  • HIV Infection

    […] dysfunction, and a bleeding tendency (particularly in people with hemophilia) Amprenavir (APV) Rash Atazanavir (ATV) Rash and yellowing of the skin and whites of the eyes (jaundice[merckmanuals.com] […] osteomalacia* Protease inhibitors with statins: myopathy Hematologic or oncologic Anemia of chronic disease Lymphoma, multiple myeloma Bone marrow infiltration (leading to pancytopenia[aafp.org] Hyperactivation is reflected in dramatic polyclonal hyperglobulinemia, only a portion of which is directed against HIV antigens;(59) bone marrow plasmacytosis;(60) heightened[hivinsite.ucsf.edu]

  • Polycythemia Neonatorum

    Gallery images and information: Diagnosis Polycythemia Neonatorum pic source Neonatal Jaundice 1 638 x 479 jpeg 79kB pic source Neonatal Jaundice 1 638 x 479 jpeg 54kB pic[mnogolok.info] Excludes1: pancytopenia (due to) (with): aplastic anemia (D61.-) bone marrow infiltration (D61.82) congenital (pure) red cell aplasia (D61.01) drug induced (D61.1) hairy[en.wikisource.org] pancytopenia D61.82 Myelophthisis Includes: Leukoerythroblastic anemia Myelophthisic anemia Panmyelophthisis Excludes 1: idiopathic myelofibrosis (D47.1) myelofibrosis NOS[app.drchrono.com]

  • Chronic Active Hepatitis

    In a patient with chronic hepatitis who has already suffered relapses a search for a second cause of jaundice is not usually necessary.[ncbi.nlm.nih.gov] Abstract A 28-year-old man was admitted to our department with intermittent fever, hepatosplenomegaly and pancytopenia.[ncbi.nlm.nih.gov] hyperglobulinemia.[hepatitiscentral.com]

  • Congenital Intrinsic Factor Deficiency

    Affected infants may experience repeated episodes of extreme anemia and jaundice.[rarediseases.org] Gene GIF (AR) Diagnostic Test Plasma Vitamin B12, Folate Neurological Ataxia, dystonia Non-Neurological Megaloblastic anemia, pancytopenia Treatment HydroxyCobalamin Level[treatable-id.org] NOS (R77.1) monoclonal gammopathy (of undetermined significance) (D47.2) Excludes2: transplant failure and rejection (T86.-) D89.0 Polyclonal hypergammaglobulinemia Benign[en.wikisource.org]

  • Hemolytic Anemia due to a Disorder of Glycolytic Enzymes

    Clinical description Clinically, PK-deficient patients suffer from a highly variable degree of chronic hemolysis, ranging from severe neonatal jaundice and fatal anemia at[orpha.net] […] and thrombotic emboli (e.g., infarctions, Budd-Chiari syndrome ) Risk of acute leukemias Think of PNH if a patient presents with hemolytic anemia, venous thrombosis, and pancytopenia[amboss.com] NOS (R77.1) monoclonal gammopathy (of undetermined significance) (D47.2) Excludes2: transplant failure and rejection (T86.-) D89.0 Polyclonal hypergammaglobulinemia Benign[en.wikisource.org]

  • Posthemorrhagic Anaemia of the Newborn

    History: Family: Anemia during pregnancy, ethnicity, jaundice in anamnesis Maternal and perinatal: Blood type and Rh; anemia; complications of labor or delivery Neonatal:[slideplayer.com] […] with malformations 284.1 Pancytopenia Excludes: pancytopenia (due to) (with): aplastic anemia NOS (284.9) bone marrow infiltration (284.2) constitutional red blood cell aplasia[theodora.com] NOS (R77.1) monoclonal gammopathy (of undetermined significance) (D47.2) Excludes2: transplant failure and rejection (T86.-) D89.0 Polyclonal hypergammaglobulinemia Benign[en.wikisource.org]

  • Anemia due to Glutathione Metabolism Disorder

    […] synthetase deficiency HNSHA due to glutathione reductase deficiency Leukocyte glucose-6-phosphate dehydrogenase deficiency Muscle phosphofructokinase deficiency Neonatal jaundice[icd9data.com] Excludes1: pancytopenia (due to) (with): aplastic anemia (D61.-) bone marrow infiltration (D61.82) congenital (pure) red cell aplasia (D61.01) drug induced (D61.1) hairy[en.wikisource.org] Anemia and jaundice are noted in the neonatal period. Jaundice may be severe enough to require exchange transfusion.[medcaretips.com]

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