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1,461 Possible Causes for Jaundice, Splenomegaly

  • Infectious Mononucleosis

    We report a case of infectious mononucleosis in a 72-year old jaundiced gentleman with ferritin level of 2438 that normalised on clinical improvement.[ncbi.nlm.nih.gov] Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] […] patient between 16 and 25 years old who complains of sore throat and fever is more likely to have infectious mononucleosis than another disease; and if - in addition - he is jaundiced[ncbi.nlm.nih.gov]

  • Hereditary Spherocytosis

    This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist[ncbi.nlm.nih.gov] Due to the membrane defect, there is increased fragility, hemolytic anemia, marked splenomegaly and hyperbilirubinemia.[ncbi.nlm.nih.gov] MATERIALS AND METHODS: A retrospective review was conducted to evaluate all SILS for splenomegaly performed by a single surgeon.[ncbi.nlm.nih.gov]

  • Pyruvate Kinase Deficiency

    Pyruvate kinase deficiency may cause pregnancy-associated jaundice.[ncbi.nlm.nih.gov] Significant hyperbilirubinaemia, anemia, and splenomegaly are common features in patients with severe haemolysis due to pyruvate kinase (PK) deficiency.[ncbi.nlm.nih.gov] She is doing well with mild splenomegaly.[ncbi.nlm.nih.gov]

  • Thalassemia

    Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[orpha.net] Approach to the adult patient with splenomegaly and other splenic disorders. . Accessed June 14, 2016. Splenomegaly. Merck Manual Professional Version. .[mayoclinic.org] Diagnostic methods Diagnosis is suspected in infants younger than 2 years of age with severe microcytic anemia, mild jaundice and hepatosplenomegaly.[orpha.net]

  • Hemolytic Anemia

    The existence of a primary form of acquired hemolytic jaundice has been questioned more and FULL TEXT[annals.org] It results in hemolytic anemia and splenomegaly.[icd9data.com] […] suffer from a mild hemolytic anemia (Hb levels ranging from 10 to 12.7g/mL) associated with macrocytosis, reticulocytosis, hyperbilirubinemia, hyperferritinemia and slight splenomegaly[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Secondary AIHA might not be diagnosed appropriately because the obstructive jaundice observed in type 1 AIP/IgG4-SC can obscure the presence of hemolytic jaundice.[ncbi.nlm.nih.gov] Examination demonstrated scleral icterus, splenomegaly, and anemia. By peripheral blood smear, the patient was diagnosed with Plasmodium ovale.[ncbi.nlm.nih.gov] Abstract A 48 year old lady presented with jaundice and exertional breathlesness.[ncbi.nlm.nih.gov]

  • Alpha Thalassemia

    BACKGROUND: Hereditary spherocytosis (HS) is a common inherited hemolytic anemia characterized by heterogeneous clinical presentations with variable degrees of anemia, jaundice[ncbi.nlm.nih.gov] Patients have variable microcytic hypochromic hemolytic anemia, splenomegaly (50 to 80%) and less commonly hepatomegaly (50%), mild jaundice (20-40%), and mild-to-moderate[orpha.net] Three deletions: Hb H Disease Patients with three alpha-globin deletions display a symptomatic microcytic anemia with moderate extravascular hemolysis that may yield splenomegaly[pathwaymedicine.org]

  • Niemann-Pick Disease Type C

    Abstract A three-month old Chinese male infant was a victim of neonatal hepatitis presenting with prolonged jaundice, poor body weight gain, progressive hepatosplenomegaly[ncbi.nlm.nih.gov] We report an unusual presentation of NPCD in a young asymptomatic adult with isolated nodular splenomegaly.[ncbi.nlm.nih.gov] NP-C) is a lysosomal lipid storage disease (see this term) characterized by variable clinical signs, depending on the age of onset, such as prolonged unexplained neonatal jaundice[orpha.net]

  • Alcoholic Hepatitis

    BACKGROUND: Alcoholic hepatitis (AH) is a severe manifestation of alcohol-related liver disease characterised by jaundice and liver failure.[ncbi.nlm.nih.gov] Image studies showed an extremely enlarged fatty liver and splenomegaly.[ncbi.nlm.nih.gov] Splenomegaly is uncommon. Ascites and hepatic encepalopathy are common in severe disease but varices are not common.[euroliver.org]

  • Portal Hypertension

    […] and left abdominal pain or fullness as a result Because portal hypertension is commonly caused by cirrhosis, liver failure symptoms can also indicate portal hypertension: Jaundice[radiology.ucla.edu] We performed LS in 83 patients with massive splenomegaly ( 30 cm) secondary to portal hypertension and liver cirrhosis.[ncbi.nlm.nih.gov] Symptoms Ascites (fluid build-up in the abdomen) Weight loss (malnutrition) Enlarged liver (at times) Varicose veins of the esophagus (varices) – with possible bleeding Jaundice[vascularcures.org]

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