Possible Causes for joint hypermobility Supination Injury Details about the project - category Details about the project - value Project status: Published Project manager: Daniel Fong Supervisor(s): Kai-Ming Chan Coworker(s): Yosuke Shima, Tron Krosshaug, Patrick Yung, Y Hong Description Over the years, ankle kinematics has been studied during simulated sub-injury or[…] [ostrc.no] Mucopolysaccharidosis Hypermobility of all the joints was noted. The limbs were normal in length. There was marked hepatosplenomegaly with coarse facies and abnormal gait. [sajr.org.za] Marfan Syndrome Physical examination revealed a lens dislocation with strabismus, high palate, positive wrist and thumb signs, joint hypermobility, and pes planus. [ncbi.nlm.nih.gov] Skeletal involvement is often the first sign of the disease and can include dolichostenomelia (excessive length of extremities), large size, arachnodactyly, joint hypermobility [orpha.net] Postural Orthostatic Tachycardia Syndrome Impact of joint laxity and hypermobility on the musculoskeletal system. J Am Acad Orthop Surg. 2011;19:463–471. [springermedizin.de] hypermobility. [acc.org] Joint hypermobility syndrome (JHS) is an inherited condition characterized by joint hypermobility, connective tissue fragility, and soft velvety skin with variable hyperextensibility [bjmp.org] Mucopolysaccharidosis Type 4 Short stature. ligamentous laxity/joint hypermobility. Odontoid hypoplasia leading to atlantoaxial instability. Spinal cord compression leading to cervical myelopathy. [genetics4medics.com] Joint hypermobility (of the wrist in particular) may develop and can be especially helpful in establishing clinical suspicion as it is unique to MPS IVA and MPS IVB among [omicsonline.org] Hypermobility of all the joints was noted. The limbs were normal in length though they appeared long in relation to the trunk. There was marked hepatosplenomegaly. [ijo.in] Hypermobility Syndrome Treating joint hypermobility syndrome There's no cure for joint hypermobility syndrome. [nhs.uk] Review of the Literature A search for the terms hypermobility, hypermobility syndrome, joint hypermobility, and benign joint hypermobility syndrome on MED-LINE and the MD [web.archive.org] Although perceived as a rare condition, joint hypermobility syndrome is common. Its prevalence in rheumatology clinics is extremely high. [ncbi.nlm.nih.gov] Mucopolysaccharidosis Type 4A In addition, joint hypermobility is unique to MPS IV. [ncbi.nlm.nih.gov] Ligamentous laxity contributes to joint instability and hypermobility, and may be detrimental in patients suffering from dysplasia of the vertebral column. [symptoma.com] Hypermobility and ulnar deviation of the wrist joint are distinctive features of MPS IVA. [ncbi.nlm.nih.gov] Arterial Tortuosity Syndrome The main findings included aged appearance, congenital joint hypermobility, joint instability complications, chronic fatigue syndrome, progressive painful joint stiffness, [ncbi.nlm.nih.gov] We conclude that patients of Kurdish origin who display arterial tortuosity associated with skin hyperextensibility, joint hypermobility, and characteristic facial features [ncbi.nlm.nih.gov] In addition, patients display connective tissue features which include hyperextensible skin, hypermobility of joints and characteristic facial features. [ncbi.nlm.nih.gov] Dopamine Beta-Hydroxylase Deficiency Less common features include an unusually large range of joint movement (hypermobility) and muscle weakness. Dopamine β-hydroxylase deficiency is a very rare disorder. [ghr.nlm.nih.gov] Ehlers-Danlos Syndrome No excess risks for adverse pregnancy outcome were seen in joint hypermobility syndrome. [ncbi.nlm.nih.gov] Beighton score and hypermobility at other joints were influenced by age at diagnosis. [ncbi.nlm.nih.gov] Implications for rehabilitation Fatigue is a significant symptom reported by individuals affected by joint hypermobility syndrome/Ehlers-Danlos syndrome - hypermobility type [ncbi.nlm.nih.gov] Ehlers-Danlos Syndrome Classic-Like Type 1 Hypermobility of Joints 4th Edition follows the same format as its successful predecessors. [books.google.com] hypermobility tenascin-X Joint hypermobility is a common finding, differing strongly between sexes and among races. 1 Joint hypermobility is not a disease in itself, but [ard.bmj.com] hypermobility, skin hyperextensibility and easy bruising without atrophic scarring. [orpha.net] Ehlers-Danlos Syndrome Type 4 The first is joint hypermobility (often called loose or double joints). [forgottendiseases.org] Skin hyperextensibility and joint hypermobility are not hallmarks of this subtype of EDS. [omicsonline.org] Soft, hyperextensible skin; joint hypermobility; bruising; normal scar formation Dominant (rare recessives) COL5A1 and COL5A2 Classical EDS Hypermobility Type (EDS type III [uwcpdx.org] Stickler Syndrome Type 2 hypermobility Double-Jointed Flexible joints Increased mobility of joints [ more ] 0001382 Long fingers 0100807 Malar flattening Zygomatic flattening 0000272 Micrognathia [rarediseases.info.nih.gov] hypermobility. [nature.com] Figure 5 Joint hypermobility: (A) MS71 I:1, (B) MS67 I:1. [jmg.bmj.com] Keratoglobus Some concomitant abnormalities reported with kertoglobus include joint hypermobility, dental and skeletal abnormalities, osteal fragility, and deafness. [ncbi.nlm.nih.gov] Three patients (3 eyes) had blue sclera, joint hypermobility, and consanguineous parents; 3 other patients (4 eyes) had only KGB. [ncbi.nlm.nih.gov] He had hypermobility of large joints, easy bruising, thin and hyperextensible skin with visible veins, which were also described in his elder brother. [ncbi.nlm.nih.gov] Hallermann-Streiff Syndrome hypermobility Double-Jointed Flexible joints Increased mobility of joints [ more ] 0001382 Low-set ears Low set ears Lowset ears [ more ] 0000369 Metaphyseal widening Broad [rarediseases.info.nih.gov] hypermobility Hypotrichosis of the scalp Metaphyseal widening Obstructive sleep apnea Parietal bossing Pectus excavatum Platybasia Recurrent respiratory infections Recurrent [dovemed.com] […] typical 0000752 Hyperlordosis Prominent swayback 0003307 Hypertension 0000822 Hypotrichosis of the scalp Reduced/lack of hair on scalp 0004782 Iris coloboma Cat eye 0000612 Joint [rarediseases.info.nih.gov] Stickler Syndrome The systemic abnormalities included short stature and joint hypermobility. The diagnosis was type 1 Stickler syndrome, and the eyes were treated surgically. [ncbi.nlm.nih.gov] There is joint hypermobility which declines with age. Osteoarthritis develops typically in the third or fourth decade. [ncbi.nlm.nih.gov] hypermobility mild spondyloepiphyseal dysplasia precocious osteoarthritis Promoted articles (advertising) [radiopaedia.org] Osteogenesis Imperfecta Type 15 The mother had velvety skin and small-joint hypermobility. [emedicine.medscape.com] Hyperextensibility" [1] Associated Co-morbidities Joint hypermobility Hearing impairment/Loss Excessive diaphoresis Cardiovascular complications Scoliosis Pectus deformity [physio-pedia.com] hypermobility and kyphoscoliosis, hernias, and arcus senilis are quite common.[ 1 ],[ 2 ] Individuals with OI type I have distinctly blue sclerae which remain intensely blue [edoj.org.eg] Orthostatic Intolerance due to NET Deficiency The lack of clinical distinction between the hypermobility type of Ehlers–Danlos syndrome and the joint hypermobility syndrome (a.k.a. hypermobility syndrome). Am. J. [doi.org] GPs should have a high index of suspicion in joint hypermobility syndrome, chronic fatigue syndrome, and diabetes. [doi.org] Other Conditions associated with PoTS Joint Hypermobility Syndrome Joint hypermobility syndrome (JHS) which is also called benign joint hypermobility syndrome, Ehlers-Danlos [potsuk.org] Oculo-Palato-Cerebral Syndrome […] rare disorder characterized by low birth weight, microcephaly, persistent hyperplastic primary vitreous, microphthalmia, large ears, small hands and feet, cleft palate, joint [malacards.org] hypermobility, developmental delay, and cerebral atrophy (summary by Pellegrino et al., 2001). (257910) (Updated 05-Apr-2021) MalaCards based summary : Oculopalatocerebral [malacards.org] hypermobility, developmental delay, and cerebral atrophy. [ncbi.nlm.nih.gov] Hyperextensible Joints It may be useful to think of it like this: Generalised joint hypermobility symptoms joint hypermobility syndrome Who gets joint hypermobility? [versusarthritis.org] Treating joint hypermobility syndrome There's no cure for joint hypermobility syndrome. [nhs.uk] Questions physicians should ask patients to detect benign joint hypermobility syndrome. [jaoa.org] Coffin-Lowry Syndrome hypermobility, hyperextensibility of interpharyngeal joint, deformity of middle finger, fixed position of forearm and thoracolumbar scoliosis. [alliedacademies.org] Hypotonia, hyperextensible fingers and hypermobility of the joint were seen. Based on these findings, he was diagnosed as having Coffin-Lowry syndrome. [koreamed.org] […] lower lip, prominent low set ears, long Philtrum, high palate, hypodentia, widespaced teeth, micrognathia, large soft hands with tapering fingers, flat feet, lax ligaments, joint [alliedacademies.org] Oculocerebrorenal Syndrome However, the only musculoskeletal abnormalities reported in patients with OCRS have been joint hypermobility, recurrent fractures, rickets, tenosynovitis, and joint effusions [ncbi.nlm.nih.gov] * Hydrophthalmos * Epicanthal folds * Flabby muscles * Joint hypermobility * Rickets * Underdeveloped testes * Excess fatty tissue Causes - Lowe oculocerebrorenal syndrome [checkorphan.org] Musculoskeletal abnormalities such as joint hypermobility, dislocated hips, and fractures may develop as consequences of renal tubular acidosis and hypophosphatemia. [uniprot.org] Ehlers-Danlos Syndrome Hypermobility Type Symptoms / Comorbidities of Joint Hypermobility syndrome/Ehlers-Danlos syndrome – Hypermobility Type often includes, but are not limited to: – Joint hypermobility (not to [edswellness.org] Hypermobility type (formerly type III) Joint hypermobility is the major manifestation of this form of Ehlers-Danlos syndrome. [medicinenet.com] hypermobility (small and large joints) which is assessed by using the Beighton Score system and a questionnaire. [rarediseases.info.nih.gov] Ehlers-Danlos Syndrom Classic Type 2 Keywords Fibromyalgia; Ehlers-Danlos syndrome hypermobility type; Skin ultrastructure; Joint hypermobility syndrome; Connective tissue disorder. [omicsonline.org] The first is joint hypermobility (often called loose or double joints). [forgottendiseases.org] Abstract The type II (mitis) variant of Ehlers-Danlos syndrome (EDS) is an autosomal dominant disorder characterized by mild skin hyperextensibility, mild joint hypermobility [mdedge.com] Ehlers-Danlos-Syndrome Type 10 hypermobility and cutaneous hyperextensibility. [orpha.net] An inherited connective tissue disorder characterized by loose and fragile skin and joint hypermobility. [icd10data.com] Soft, hyperextensible skin; joint hypermobility; bruising; normal scar formation Dominant (rare recessives) COL5A1 and COL5A2 Classical EDS Hypermobility Type (EDS type III [uwcpdx.org] Dermatosparaxis Joint hypermobility becomes more important with age. [ncbi.nlm.nih.gov] The patients suffer with soft, doughy, saggy, redundant and fragile skin, different types of hernias and joint hypermobility. [xpertdox.com] Common symptoms include soft, doughy skin that is extremely fragile; saggy, redundant skin, especially on the face; hernias; and mild to severe joint hypermobility. [oneedsvoice.com] Brittle Cornea Syndrome Type 2 hypermobility (generalized or restricted to small joints). [ehlers-danlos.com] Most types of EDS affect joints and skin and most feature joint hypermobility. [patient.info] Victoria has Ehlers-Danlos syndrome (EDS), a group of connective tissue disorders generally characterized by joint hypermobility, skin hyperextensibility, and tissue fragility [raredr.com] Brittle Cornea Syndrome Type 1 […] of the joints. [genecards.org] One carrier had partially penetrant features of BCS1, including joint hypermobility. [ncbi.nlm.nih.gov] hypermobility (generalized or restricted to small joints). [ehlers-danlos.com] Rubinstein-Taybi Syndrome hypermobility, and skin anomalies (in particular keloid formation). [orpha.net] A small group of patients experience an increased fracture frequency, and many patients have joint hypermobility and lax ligaments that cause various orthopedic problems. [doi.org] […] nasolacrimal duct obstruction, congenital glaucoma, refractive errors), a variety of congenital heart defects (e.g. ventricular and atrial septal defect, patent ductus arteriosus), joint [orpha.net] Atkin Syndrome Germany, Deutsche, Deutschlandneuropathologist BEIGHTON, GretaBeighton Score (1971)19392017England, English, UK, British, South Africanursing, genetics, historygenetics, hypermobility [litfl.com] score, laxity, joint PAGON, Roberta AndersonPagon syndrome (1985)1945USA, America, AmericanPaediatrician, pediatrics, genetics LANCEFIELD, Rebecca CraighillLancefield classification [litfl.com]
