Joint Hypermobility: Causes & Reasons

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Possible Causes for Joint Hypermobility

Hypermobility Syndrome

Treating joint hypermobility syndrome There's no cure for joint hypermobility syndrome. [nhs.uk]

Review of the Literature A search for the terms hypermobility, hypermobility syndrome, joint hypermobility, and benign joint hypermobility syndrome on MED-LINE and the MD [web.archive.org]

Neuromusculoskeletal signs and potential sequelae from benign joint hypermobility syndrome. Figure 2. [jaoa.org]

Ehlers-Danlos Syndrome

No excess risks for adverse pregnancy outcome were seen in joint hypermobility syndrome. [ncbi.nlm.nih.gov]

[…] syndrome (EDS-HT) or benign joint hypermobility syndrome (BJHS). [ncbi.nlm.nih.gov]

Implications for rehabilitation Fatigue is a significant symptom reported by individuals affected by joint hypermobility syndrome/Ehlers-Danlos syndrome - hypermobility type [ncbi.nlm.nih.gov]

Mucopolysaccharidosis Type 4

Short stature. ligamentous laxity/joint hypermobility. Odontoid hypoplasia leading to atlantoaxial instability. Spinal cord compression leading to cervical myelopathy. [genetics4medics.com]

Joint hypermobility (of the wrist in particular) may develop and can be especially helpful in establishing clinical suspicion as it is unique to MPS IVA and MPS IVB among [omicsonline.org]

Hypermobility of all the joints was noted. The limbs were normal in length though they appeared long in relation to the trunk. There was marked hepatosplenomegaly. [ijo.in]

Ehlers-Danlos Syndrome Classic-Like Type 1

hypermobility (GJH) and benign joint hypermobility syndrome (BJHS). [citeulike.org]

hypermobility tenascin-X Joint hypermobility is a common finding, differing strongly between sexes and among races. 1 Joint hypermobility is not a disease in itself, but [ard.bmj.com]

Soft, hyperextensible skin; joint hypermobility; bruising; normal scar formation Dominant (rare recessives) COL5A1 and COL5A2 Classical EDS Hypermobility Type (EDS type III [uwcpdx.org]

Stickler Syndrome Type 2

hypermobility mild spondyloepiphyseal dysplasia precocious osteoarthritis Promoted articles (advertising) [radiopaedia.org]

Hearing loss, joint hypermobility and premature arthropathy are frequently found in Stickler syndrome, but are less specific. [ashg.org]

hypermobility Double-Jointed Flexible joints Increased mobility of joints [ more ] 0001382 Long fingers 0100807 Malar flattening Zygomatic flattening 0000272 Micrognathia [rarediseases.info.nih.gov]

Oculocerebrorenal Syndrome

However, the only musculoskeletal abnormalities reported in patients with OCRS have been joint hypermobility, recurrent fractures, rickets, tenosynovitis, and joint effusions [ncbi.nlm.nih.gov]

* Hydrophthalmos * Epicanthal folds * Flabby muscles * Joint hypermobility * Rickets * Underdeveloped testes * Excess fatty tissue Causes - Lowe oculocerebrorenal syndrome [checkorphan.org]

Musculoskeletal abnormalities such as joint hypermobility, dislocated hips, and fractures may develop as consequences of renal tubular acidosis and hypophosphatemia. [uniprot.org]

Marfan Syndrome

Physical examination revealed a lens dislocation with strabismus, high palate, positive wrist and thumb signs, joint hypermobility, and pes planus. [ncbi.nlm.nih.gov]

Skeletal involvement is often the first sign of the disease and can include dolichostenomelia (excessive length of extremities), large size, arachnodactyly, joint hypermobility [orpha.net]

Osteogenesis Imperfecta Type 15

The mother had velvety skin and small-joint hypermobility. [emedicine.medscape.com]

hypermobility and kyphoscoliosis, hernias, and arcus senilis are quite common.[ 1 ],[ 2 ] Individuals with OI type I have distinctly blue sclerae which remain intensely blue [edoj.org.eg]

Hyperextensibility" [1] Associated Co-morbidities Joint hypermobility Hearing impairment/Loss Excessive diaphoresis Cardiovascular complications Scoliosis Pectus deformity [physio-pedia.com]

Osteoporosis-Pseudoglioma Syndrome

hypermobility Double-Jointed Flexible joints Increased mobility of joints [ more ] 0001382 Kyphoscoliosis 0002751 Metaphyseal widening Broad wide portion of long bone 0003016 [rarediseases.info.nih.gov]

[…] disability, mild Mental retardation, borderline-mild Mild and nonprogressive mental retardation Mild mental retardation [ more ] 0001256 Iris atrophy Iris degeneration 0001089 Joint [rarediseases.info.nih.gov]

Dopamine Beta-Hydroxylase Deficiency

Less common features include an unusually large range of joint movement (hypermobility) and muscle weakness. Dopamine β-hydroxylase deficiency is a very rare disorder. [ghr.nlm.nih.gov]

Rubinstein-Taybi Syndrome

hypermobility, and skin anomalies (in particular keloid formation). [orpha.net]

hypermobility Double-Jointed Flexible joints Increased mobility of joints [ more ] 0001382 Joint laxity Joint instability Lax joints Loose-jointedness Loosejointedness [ [rarediseases.info.nih.gov]

[…] nasolacrimal duct obstruction, congenital glaucoma, refractive errors), a variety of congenital heart defects (e.g. ventricular and atrial septal defect, patent ductus arteriosus), joint [orpha.net]

Autosomal Recessive Cutis Laxa Type 2A

hypermobility Double-Jointed Flexible joints Increased mobility of joints [ more ] 0001382 Lipodystrophy Inability to make and keep healthy fat tissue 0009125 Long philtrum [rarediseases.info.nih.gov]

Mental retardation, nonspecific Mental-retardation [ more ] 0001249 Intrauterine growth retardation Prenatal growth deficiency Prenatal growth retardation [ more ] 0001511 Joint [rarediseases.info.nih.gov]

Mucopolysaccharidosis Type 4A

In addition, joint hypermobility is unique to MPS IV. [ncbi.nlm.nih.gov]

Ligamentous laxity contributes to joint instability and hypermobility, and may be detrimental in patients suffering from dysplasia of the vertebral column. [symptoma.com]

Hypermobility and ulnar deviation of the wrist joint are distinctive features of MPS IVA. [ncbi.nlm.nih.gov]

Mirhosseini-Holmes-Walton Syndrome

hypermobility 31 HP:0001382 9 reduced visual acuity 31 HP:0007663 10 truncal obesity 31 HP:0001956 11 narrow palm 31 HP:0004283 12 hypogonadism 31 HP:0000135 13 pigmentary [malacards.org]

[…] unclassified Phenotypes Arachnodactyly ; Autosomal recessive inheritance ; Cataract ; Hypogonadism ; Intellectual disability, progressive ; Intellectual disability, severe ; Joint [dev.mousephenotype.org]

hypermobility pigmentary retinopathy, myopia, and intermittent neutropenia. [en.academicresearch.net]

3M Syndrome

Skeletal features include hyperlordosis, short digits, prominent heels, winged scapulae, pes planus and joint hypermobility and dislocation (5). [edm.bioscientifica.com]

De Barsey-Moens-Dierckx Syndrome

[…] dislocation-lax skin Mental retardation joint hypermobility and skin laxity with or without metabolic abnormalities Neurocutaneous syndrome Bicknell type Progeroid syndrome [uniprot.org]

hypermobility; abnormal range of joint movement Large fontanelles; large soft spots/gaps between the cranial bones Low-set ears Macrotia; abnormally-large ears Muscular hypotonia [dovemed.com]

In these disorders, there are excessive joint mobility (joint hypermobility) problems. [findzebra.com]

Vesicoureteral Reflux 8

The hypermobility type is characterized by an unusually large range of joint movement (hypermobility). [selfdecode.com]

This condition causes hypermobility and chronic joint pain. [ghr.nlm.nih.gov]

hypermobility. [ingentaconnect.com]

Mucopolysaccharidosis

Hypermobility of all the joints was noted. The limbs were normal in length. There was marked hepatosplenomegaly with coarse facies and abnormal gait. [sajr.org.za]

Hallermann-Streiff Syndrome

hypermobility Double-Jointed Flexible joints Increased mobility of joints [ more ] 0001382 Low-set ears Low set ears Lowset ears [ more ] 0000369 Metaphyseal widening Broad [rarediseases.info.nih.gov]

hypermobility Hypotrichosis of the scalp Metaphyseal widening Obstructive sleep apnea Parietal bossing Pectus excavatum Platybasia Recurrent respiratory infections Recurrent [dovemed.com]

[…] typical 0000752 Hyperlordosis Prominent swayback 0003307 Hypertension 0000822 Hypotrichosis of the scalp Reduced/lack of hair on scalp 0004782 Iris coloboma Cat eye 0000612 Joint [rarediseases.info.nih.gov]

Coffin-Lowry Syndrome

hypermobility, hyperextensibility of interpharyngeal joint, deformity of middle finger, fixed position of forearm and thoracolumbar scoliosis. [alliedacademies.org]

Hypotonia, hyperextensible fingers and hypermobility of the joint were seen. Based on these findings, he was diagnosed as having Coffin-Lowry syndrome. [koreamed.org]

[…] lower lip, prominent low set ears, long Philtrum, high palate, hypodentia, widespaced teeth, micrognathia, large soft hands with tapering fingers, flat feet, lax ligaments, joint [alliedacademies.org]

Langer-Giedion Syndrome

Children with TRPS II often have an unusually large range of joint movement (hypermobility). [ghr.nlm.nih.gov]

However, as osteochondromas begin to develop, typically starting between infancy and mid-childhood, the joints begin to stiffen, leading to decreased mobility. [ghr.nlm.nih.gov]

Wilson Disease

hypermobility Double-Jointed Flexible joints Increased mobility of joints [ more ] 0001382 Mixed demyelinating and axonal polyneuropathy 0007327 Nephrolithiasis Kidney stones [rarediseases.info.nih.gov]

Hypercalciuria Elevated urine calcium levels 0002150 Hyperphosphaturia High urine phosphate levels 0003109 Hypoparathyroidism Decreased parathyroid hormone secretion 0000829 Joint [rarediseases.info.nih.gov]

Nemaline Myopathy Type 7

hypermobility May develop joint and spine abnormalities ( J Med Genet 1997;34:705 ) Congenital forms often show facial elongation, tent shaped mouth and high arched palate [pathologyoutlines.com]

[…] be seen with specific mutations ( Curr Opin Neurol 2016;29:642, Semin Cell Dev Biol 2017;64:191, Circulation 1989;79:1282 ) Frequently show weak deep tendon reflexes and joint [pathologyoutlines.com]

Atkin Syndrome

Germany, Deutsche, Deutschlandneuropathologist BEIGHTON, GretaBeighton Score (1971)19392017England, English, UK, British, South Africanursing, genetics, historygenetics, hypermobility [litfl.com]

score, laxity, joint PAGON, Roberta AndersonPagon syndrome (1985)1945USA, America, AmericanPaediatrician, pediatrics, genetics LANCEFIELD, Rebecca CraighillLancefield classification [litfl.com]

Supination Injury

Please use this identifier to cite or link to this item: https://dspace.lboro.ac.uk/2134/21212 Title: Biomechanics of supination ankle sprain: a case report of an accidental injury event in the laboratory Authors: Hong, Youlian Shima, Yosuke Krosshaug, Tron Yung, Patrick Shu-Hang Chan, Kai-Ming Keywords: Ankle sprain[…] [dspace.lboro.ac.uk]

Orthostatic Intolerance due to NET Deficiency

Other Conditions associated with PoTS Joint Hypermobility Syndrome Joint hypermobility syndrome (JHS) which is also called benign joint hypermobility syndrome, Ehlers-Danlos [potsuk.org]

The lack of clinical distinction between the hypermobility type of Ehlers–Danlos syndrome and the joint hypermobility syndrome (a.k.a. hypermobility syndrome). Am. J. [doi.org]

GPs should have a high index of suspicion in joint hypermobility syndrome, chronic fatigue syndrome, and diabetes. [doi.org]

Postural Orthostatic Tachycardia Syndrome

Impact of joint laxity and hypermobility on the musculoskeletal system. J Am Acad Orthop Surg. 2011;19:463–471. [springermedizin.de]

hypermobility. [acc.org]

Joint hypermobility syndrome (JHS) is an inherited condition characterized by joint hypermobility, connective tissue fragility, and soft velvety skin with variable hyperextensibility [bjmp.org]

Arterial Tortuosity Syndrome

The main findings included aged appearance, congenital joint hypermobility, joint instability complications, chronic fatigue syndrome, progressive painful joint stiffness, [ncbi.nlm.nih.gov]

We conclude that patients of Kurdish origin who display arterial tortuosity associated with skin hyperextensibility, joint hypermobility, and characteristic facial features [ncbi.nlm.nih.gov]

In addition, patients display connective tissue features which include hyperextensible skin, hypermobility of joints and characteristic facial features. [ncbi.nlm.nih.gov]

Ehlers-Danlos Syndrome Type 4

The first is joint hypermobility (often called loose or double joints). [forgottendiseases.org]

Soft, hyperextensible skin; joint hypermobility; bruising; normal scar formation Dominant (rare recessives) COL5A1 and COL5A2 Classical EDS Hypermobility Type (EDS type III [uwcpdx.org]

Most types of EDS affect joints and skin and most feature joint hypermobility. [patient.info]

Keratoglobus

Some concomitant abnormalities reported with kertoglobus include joint hypermobility, dental and skeletal abnormalities, osteal fragility, and deafness. [ncbi.nlm.nih.gov]

Three patients (3 eyes) had blue sclera, joint hypermobility, and consanguineous parents; 3 other patients (4 eyes) had only KGB. [ncbi.nlm.nih.gov]

He had hypermobility of large joints, easy bruising, thin and hyperextensible skin with visible veins, which were also described in his elder brother. [ncbi.nlm.nih.gov]