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827 Possible Causes for Joint Stiffness, Muscle Weakness, Progressive Contractures

  • Congenital Muscular Dystrophy

    KEYWORDS: Collagen; Fibrosis; IGF-1; Mesenchymal; Mouse; Muscular dystrophy; Skeletal muscles; Weakness[ncbi.nlm.nih.gov] We report the first known Egyptian patient with FCMD, established by clinical features of generalized weakness, pseudohypertrophy of calf muscles, progressive joint contractures[ncbi.nlm.nih.gov] CMD results in overall muscle weakness with possible joint stiffness or looseness.[mda.org]

  • Rheumatoid Arthritis

    Fatigue, muscle weakness, and weight loss are common symptoms.[britannica.com] Erosion of the articular cartilage, together with ligamentous changes, result in deformity and contractures. As the disease progresses, pain and deformity increase.[orthoinfo.aaos.org] The common signs include joint stiffness, swelling, pain, redness and warmth. These are typical hallmarks of inflammation.[techtimes.com]

  • Fibrodysplasia Ossificans Progressiva

    * Malformed fingers * Malformed toes * Limited joint movement * Muscle weakness * Rigid muscles * Tendon weakness * Rigid tendons * Calcium deposits in muscles * Movement[checkorphan.org] This case however presents a very aggressive form of disease with patient developing spontaneous swellings and progressive contractures.[ijcasereportsandimages.com] Tissue swelling, joint stiffness and serious discomfort can occur. Some may have a low-grade fever. Flare-ups can last as long as six to eight weeks.[ucsfbenioffchildrens.org]

  • Hemophilia

    Weak muscles don't support the joints as well, making bleeding episodes more frequent.[web.archive.org] This disease can lead to further symptoms such as: • progressive decreased motion • flexion contractures • muscle atrophy [1] The second most common presentation of hemophilia[physio-pedia.com] Ultimately this process will cause chronic joint stiffness and pain.[emedicinehealth.com]

  • Mucopolysaccharidosis

    Compression of the cervical spinal cord, caused by glycosaminoglycan infiltration of the dura, may lead to spastic paresis if not corrected by neurosurgical intervention.[orpha.net] ; hip containment surgeries; corrective osteotomy for progressive valgus deformity at the knee; posterior spinal fusion Multispecialty care is mandatory for these patients[emedicine.medscape.com] Nursing Diagnosis - Self care deficit related to inability to carryout ADLS / tremors - Impaired physical mobility related to weakness of bones and muscles - Risk for injury[slideshare.net]

  • Arthrogryposis Multiplex Congenita

    This condition is accompanied by increased muscle weakness. Physical therapist Lynn Grabe of Children’s Hospital in St. Paul, MN details Anna’s aquatic therapy journey.[hydroworx.com] Abstract Arthrogryposis multiplex congenita (AMC) is a rare disorder characterized by non-progressive, multiple contractures.[ncbi.nlm.nih.gov] Arthrogryposis multiplex congenita (AMC) is a complex disorder that leads to joint stiffness and deformities in 2 or more joints in afflicted children.[ncbi.nlm.nih.gov]

  • Osteoarthritis

    As a progressive degenerative joint disorder, OA is characterized by cartilage damage, changes in the subchondral bone, osteophyte formation, muscle weakness, and inflammation[ncbi.nlm.nih.gov] Another characteristic symptom of the disease is the progressive incapacity of the joint to function, leading – in the long run – to loss of mobility.[oafifoundation.com] The absolute reduction in finger joint stiffness for the exercise group, compared with the control group, was 7% (3% to 10%).[ncbi.nlm.nih.gov]

  • Muscle Spasticity

    Muscle weakness and spasticity will be evaluated in both groups of subjects.[clinicaltrials.gov] Spasticity-related muscle dysfunction is characterized by muscle hyperactivity/hypertonicity, motor weakness, and, in progressed cases, contracture of adjacent soft tissue[bmcneurol.biomedcentral.com] BACKGROUND: Skeletal muscle spasticity is a major physical complication resulting from traumatic brain injury (TBI), which can lead to muscle contracture, joint stiffness,[ncbi.nlm.nih.gov]

  • Progressive Pseudorheumatoid Dysplasia

    INTERPRETATION: The deficits can be attributed to pronounced muscle weakness plus functional joint impairment and pain.[ncbi.nlm.nih.gov] These joints develop progressive contractures.[ncbi.nlm.nih.gov] Typical signs are prominent epiphysis, progressive joint stiffness, muscle weakness and early fatigue [ 1 ].[ped-rheum.biomedcentral.com]

  • Emery-Dreifuss Muscular Dystrophy

    In some of the patients, muscle weakness distribution was more widespread than has usually been reported, with prominent involvement of finger extensors.[ncbi.nlm.nih.gov] Abstract Emery-Dreifuss muscular dystrophy (EDMD) is a neuromuscular disorder resulting in progressive muscle weakness, contractures, and cardiomyopathy.[ncbi.nlm.nih.gov] The condition causes slowly progressive (worsening) weakness in the muscles of the shoulders, upper arms, and lower legs and joint stiffness (contractures).[nationwidechildrens.org]

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