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827 Possible Causes for Joint Stiffness, Muscle Weakness, Progressive Contractures

  • Congenital Muscular Dystrophy

    KEYWORDS: Collagen; Fibrosis; IGF-1; Mesenchymal; Mouse; Muscular dystrophy; Skeletal muscles; Weakness[] We report the first known Egyptian patient with FCMD, established by clinical features of generalized weakness, pseudohypertrophy of calf muscles, progressive joint contractures[] CMD results in overall muscle weakness with possible joint stiffness or looseness.[]

  • Rheumatoid Arthritis

    Fatigue, muscle weakness, and weight loss are common symptoms.[] Erosion of the articular cartilage, together with ligamentous changes, result in deformity and contractures. As the disease progresses, pain and deformity increase.[] The common signs include joint stiffness, swelling, pain, redness and warmth. These are typical hallmarks of inflammation.[]

  • Fibrodysplasia Ossificans Progressiva

    * Malformed fingers * Malformed toes * Limited joint movement * Muscle weakness * Rigid muscles * Tendon weakness * Rigid tendons * Calcium deposits in muscles * Movement[] This case however presents a very aggressive form of disease with patient developing spontaneous swellings and progressive contractures.[] Tissue swelling, joint stiffness and serious discomfort can occur. Some may have a low-grade fever. Flare-ups can last as long as six to eight weeks.[]

  • Hemophilia

    Weak muscles don't support the joints as well, making bleeding episodes more frequent.[] This disease can lead to further symptoms such as: • progressive decreased motion • flexion contractures • muscle atrophy [1] The second most common presentation of hemophilia[] Ultimately this process will cause chronic joint stiffness and pain.[]

  • Mucopolysaccharidosis

    Compression of the cervical spinal cord, caused by glycosaminoglycan infiltration of the dura, may lead to spastic paresis if not corrected by neurosurgical intervention.[] ; hip containment surgeries; corrective osteotomy for progressive valgus deformity at the knee; posterior spinal fusion Multispecialty care is mandatory for these patients[] Nursing Diagnosis - Self care deficit related to inability to carryout ADLS / tremors - Impaired physical mobility related to weakness of bones and muscles - Risk for injury[]

  • Arthrogryposis Multiplex Congenita

    This condition is accompanied by increased muscle weakness. Physical therapist Lynn Grabe of Children’s Hospital in St. Paul, MN details Anna’s aquatic therapy journey.[] Abstract Arthrogryposis multiplex congenita (AMC) is a rare disorder characterized by non-progressive, multiple contractures.[] Arthrogryposis multiplex congenita (AMC) is a complex disorder that leads to joint stiffness and deformities in 2 or more joints in afflicted children.[]

  • Osteoarthritis

    As a progressive degenerative joint disorder, OA is characterized by cartilage damage, changes in the subchondral bone, osteophyte formation, muscle weakness, and inflammation[] Another characteristic symptom of the disease is the progressive incapacity of the joint to function, leading – in the long run – to loss of mobility.[] The absolute reduction in finger joint stiffness for the exercise group, compared with the control group, was 7% (3% to 10%).[]

  • Muscle Spasticity

    Muscle weakness and spasticity will be evaluated in both groups of subjects.[] Spasticity-related muscle dysfunction is characterized by muscle hyperactivity/hypertonicity, motor weakness, and, in progressed cases, contracture of adjacent soft tissue[] BACKGROUND: Skeletal muscle spasticity is a major physical complication resulting from traumatic brain injury (TBI), which can lead to muscle contracture, joint stiffness,[]

  • Progressive Pseudorheumatoid Dysplasia

    INTERPRETATION: The deficits can be attributed to pronounced muscle weakness plus functional joint impairment and pain.[] These joints develop progressive contractures.[] Typical signs are prominent epiphysis, progressive joint stiffness, muscle weakness and early fatigue [ 1 ].[]

  • Emery-Dreifuss Muscular Dystrophy

    In some of the patients, muscle weakness distribution was more widespread than has usually been reported, with prominent involvement of finger extensors.[] Abstract Emery-Dreifuss muscular dystrophy (EDMD) is a neuromuscular disorder resulting in progressive muscle weakness, contractures, and cardiomyopathy.[] The condition causes slowly progressive (worsening) weakness in the muscles of the shoulders, upper arms, and lower legs and joint stiffness (contractures).[]

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