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263 Possible Causes for Joint Stiffness, Progressive Contractures, Recurrent Pneumonia

  • Rheumatoid Arthritis

    Erosion of the articular cartilage, together with ligamentous changes, result in deformity and contractures. As the disease progresses, pain and deformity increase.[orthoinfo.aaos.org] The common signs include joint stiffness, swelling, pain, redness and warmth. These are typical hallmarks of inflammation.[techtimes.com] Flexion contractures may require intensive exercise, casting, or immobilization (eg, splinting) in progressively more stretched-open positions.[merckmanuals.com]

  • Mucopolysaccharidosis 2

    Clinical manifestations include dyspnea, difficulties with clearing secretions, cough, wheezing, and recurrent bronchitis or pneumonia.[karger.com] Flexion contractures. Progressive deafness - usually mixed sensorineural/conductive variety.[patient.info] Bone and joint involvement leads to skeletal deformities and joint stiffness.[symptoma.com]

  • Mucopolysaccharidosis

    ; hip containment surgeries; corrective osteotomy for progressive valgus deformity at the knee; posterior spinal fusion Multispecialty care is mandatory for these patients[emedicine.medscape.com] This results in permanent, progressive cellular damage which affects the appearance, physical abilities, organ and system functioning and, in most cases, mental development[omicsonline.org] […] hepatosplenomegaly, dysostosis multiplex, short stature, coarse facial features, corneal clouding, joint contractures, umbilical hernias, failure to thrive, intellectual[surgicalneurologyint.com]

  • Mucopolysaccharidosis 6

    Patients are typically susceptible to developing obstructive and restrictive lung disease which are accompanied by complications such as recurrent pneumonia and obstructive[symptoma.com] , hirsutism, joint contractures, hepatosplenomegaly, short stature, and skeletal, respiratory, and cardiac abnormalities, with a characteristic pattern of a chronic and progressive[scielo.br] The major clinical manifestations are corneal clouding, joint stiffness, and a skeletal dysplasia known as dysostosis multiplex.[egl-eurofins.com]

  • Ankylosing Spondylitis

    These deformities are excessive dorsal kyphosis with compensatory cervical lordosis and hip flexion contracture.[physio-pedia.com] When vertebrae or other bones/joints fuse together, the spine becomes stiff and immobile.[spineuniverse.com] Young patients need a great deal of encouragement and support as self-worth understandably diminishes with the progression of postural deformity. [7] (LOE:5) Treatment is[physio-pedia.com]

  • Congenital Muscular Dystrophy

    Choking and recurrent pneumonia may occur. Distal. This group of rare diseases affects adult men and women.[webmd.com] We report the first known Egyptian patient with FCMD, established by clinical features of generalized weakness, pseudohypertrophy of calf muscles, progressive joint contractures[ncbi.nlm.nih.gov] CMD results in overall muscle weakness with possible joint stiffness or looseness.[mda.org]

  • Fibrodysplasia Ossificans Progressiva

    This case however presents a very aggressive form of disease with patient developing spontaneous swellings and progressive contractures.[ijcasereportsandimages.com] Tissue swelling, joint stiffness and serious discomfort can occur. Some may have a low-grade fever. Flare-ups can last as long as six to eight weeks.[ucsfbenioffchildrens.org] Her respiratory condition was complicated by recurrent recent episodes of pneumonia.[anesthesia-analgesia.org]

  • Hemiplegia

    Contractures can develop anywhere but are particular apparent in the paretic limbs. As contractures progress, edema and pain may develop and further restrict mobility.[physio-pedia.com] The purpose of this study was to investigate the immediate effect of Walkbot gait training on knee joint stiffness in an individual with spastic hemiplegia.[ncbi.nlm.nih.gov] […] be a therapeutic objective but a means for preventing contractures.[emedicine.medscape.com]

  • Systemic Scleroderma

    Aspiration pneumonia should be suspected if a scleroderma patient has recurrent pneumonia, especially if there is an overlap or related myositis that might increase the risk[omicsonline.org] With disease progression, ulcerations over joints and flexion contractures of the fingers, wrists, and elbows may occur.[aafp.org] Other signs and symptoms of systemic scleroderma from internal organ involvement may include: Joint inflammation with stiffness and pain Sores (ulcers), mostly on the fingertips[my.clevelandclinic.org]

  • Mucolipidosis

    These young patients are often plagued by recurrent respiratory tract infections, including pneumonia, otitis media (middle ear infections), and bronchitis.[ninds.nih.gov] Growth generally doesn’t progress beyond the 10th percentile and is complicated by progressive contractures.[invitae.com] However; the patients with late onset and/or mild joint stiffness experienced slowly progressive symptoms.[ncbi.nlm.nih.gov]

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