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396 Possible Causes for Joint Stiffness, Retinal Degeneration, Round Face

  • Mucopolysaccharidosis 2

    […] resulting in large rounded cheeks and thick lips – generally manifests between ages 18 months and four years in the early progressive form and about two years later for those[ncbi.nlm.nih.gov] Typical signs and symptoms include: Hearing impairment Joint stiffness Coarse face Upper airway disease Carpal tunnel syndrome Communicating hydrocephalus Retinal degeneration[symptoma.com] Retinal degeneration is seen to a lesser degree in MPS IIB. Patients diagnosed with MPS IIB can live beyond the fifth decade of life.[emedicine.medscape.com]

  • Mucopolysaccharidosis

    degeneration Hearing impairment – Deafness Musculoskeletal disease – Short stature; joint stiffness; symptoms of peripheral nerve entrapment Findings from examination may[emedicine.medscape.com] Retinal degeneration may occur, but the cornea usually remains clear. Appearance is normal at birth with excessive growth taking place during first two years of life.[icd9data.com] Corneal clouding was mentioned as another symptom characteristic of MPS and may be associated with glaucoma, retinal degeneration, and optic nerve swelling with subsequent[symptoma.com]

  • Mucopolysaccharidosis 1

    Additional signs and symptoms that may develop include: Enlarged head Chronic nasal discharge Retinal degeneration Splenomegaly Enlarged abdominal organs Skeletal dysplasia[medicinenet.com] Joint stiffness and skeletal deformities. Cardiomyopathy and coronary heart disease. Hepatosplenomegaly.[patient.info] degeneration Hearing impairment – Deafness Musculoskeletal disease – Short stature; joint stiffness; symptoms of peripheral nerve entrapment Findings from examination may[emedicine.medscape.com]

  • Congenital Muscular Dystrophy

    The eyes presented with severe myopia and retinal dysplasia.[doi.org] CMD results in overall muscle weakness with possible joint stiffness or looseness.[mda.org] There may be stiff joints (contractures) due to the baby not being able to move the joints enough.[patient.info]

  • Arthritis

    These side effects are serious and can include easy bruising, thinning of the bones (osteoporosis), cataracts, weight gain, a round face, susceptibility to infections, diabetes[orthop.washington.edu] degeneration Leflunomide 20 mg po once/day or, if adverse effects occur, reduced to 10 mg once/day Skin reactions Hepatic dysfunction Alopecia Diarrhea Peripheral neuropathy[merckmanuals.com] Arthritis is the inflammation of one or more joints. The main symptoms are joint pain, swelling and stiffness.[symptoma.com]

  • Kniest Dysplasia

    The disease also causes ocular abnormalities, such as retinopathy, vitreoretinal degeneration, cataract, glaucoma, retinal detachment, myopia.[symptoma.com] This is often true for spinal deformities such as scoliosis, hip conditions, knee complications and joint stiffness.[chop.edu] face Circular face Round facial appearance Round facial shape [ more ] 0000311 5%-29% of people have these symptoms Cataract Clouding of the lens of the eye Cloudy lens [[rarediseases.info.nih.gov]

  • Rheumatoid Arthritis

    These side effects are serious and can include easy bruising, thinning of the bones (osteoporosis), cataracts, weight gain, a round face, susceptibility to infections, diabetes[orthop.washington.edu] degeneration Leflunomide 20 mg po once/day or, if adverse effects occur, reduced to 10 mg once/day Skin reactions Hepatic dysfunction Alopecia Diarrhea Peripheral neuropathy[merckmanuals.com] The common signs include joint stiffness, swelling, pain, redness and warmth. These are typical hallmarks of inflammation.[techtimes.com]

  • Arthrogryposis Multiplex Congenita

    Round face with capillary hemangioma and slightly small jaw.[scielo.br] Ophthalmologic evaluation is done for opacity and retinal degeneration. Treatment Arthrogryposis cannot be cured. The treatment goals are ambulation and self-care.[boneandspine.com] Arthrogryposis multiplex congenita (AMC) is a complex disorder that leads to joint stiffness and deformities in 2 or more joints in afflicted children.[ncbi.nlm.nih.gov]

  • Stickler Syndrome

    Most also have a characteristic face with flat cheekbones.[dbproject.mn.org] The ocular findings, frequently bilateral, consisted of radial perivascular retinal degeneration (RPRD) (100%), vitreous syneresis (100%), high myopia (76%), retinal detachment[ncbi.nlm.nih.gov] Joint problems Hypermobility (looseness and overflexibility of joints). Stiffness and premature arthritis. Prominent joints - joints that are more visible than normal.[contact.org.uk]

  • Systemic Lupus Erythematosus

    Recent ophthalmic imaging technologies are capable of identifying early changes in retinal and choroidal morphology and circulation that may reflect CNS degeneration.[ncbi.nlm.nih.gov] The pains may 'flit' from joint to joint. Joint stiffness is common and is usually worse first thing in the morning.[patient.info] Depending on the dosage, people who require steroids may develop Cushing's syndrome, symptoms of which may include obesity, puffy round face, diabetes mellitus, increased[en.wikipedia.org]

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