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425 Possible Causes for Joint Stiffness, Round Face

  • Mucopolysaccharidosis

    A typical clinical presentation includes such symptoms and characteristics as short stature, facial dysmorphism, skeletal deformities, pulmonary dysfunction, joint stiffness[] The early clinical characteristics were developmental delay, joint stiffness, coarse facies, recurrent respiratory tract infections, abdominal distention and hernia.[] These may include joint stiffness, heart problems, corneal clouding and hearing loss.[]

  • Mucopolysaccharidosis 2

    Bone and joint involvement leads to skeletal deformities and joint stiffness.[] The phenotype of the patient was severe, including joint stiffness, kyphosis, hepatomegaly, hypertrophic cardiomyopathy, moderate mental retardation, and bilateral hearing[] […] contractures (from joint stiffness) Tests may include: Enzyme study Genetic testing for a change in the iduronate sulfatase gene Urine test for heparan sulfate and dermatan[]

  • Congenital Muscular Dystrophy

    CMD results in overall muscle weakness with possible joint stiffness or looseness.[] […] of the joints, hip dislocation and a type of curvature of the spine known as ’kyphoscoliosis’.[] There may be stiff joints (contractures) due to the baby not being able to move the joints enough.[]

  • Mucopolysaccharidosis 1

    Joint stiffness and skeletal deformities. Cardiomyopathy and coronary heart disease. Hepatosplenomegaly.[] stiffness The cause of MPS I is inherited genetic mutations on chromosome 4 that leads to deficiency in the lysosomal enzyme a-L-iduronidase.[] Symptoms include stiff painful joints, carpal tunnel syndrome, glaucoma (with potential clouding of the cornea) and aortic valvular disease.[]

  • Arthritis

    These side effects are serious and can include easy bruising, thinning of the bones (osteoporosis), cataracts, weight gain, a round face, susceptibility to infections, diabetes[] Arthritis is the inflammation of one or more joints. The main symptoms are joint pain, swelling and stiffness.[] "Arthritis" describes many different diseases that cause tenderness, pain, swelling, and joint stiffness.[]

  • Psoriasis

    Nineteen dermatologists from different European countries met for a face-to-face discussion and defined items through a four-round Delphi process.[] Psoriatic arthritis produces swelling and stiffness in the joints or stiffness in the lower back and should be managed by a rheumatologist who works closely with your dermatologist[] […] are small for gestational age Oral antihistamines and topical corticosteroids for mild cases; systemic oral corticosteroids for severe cases Impetigo herpetiformis 22, 23 Round[]

  • Rheumatoid Arthritis

    These side effects are serious and can include easy bruising, thinning of the bones (osteoporosis), cataracts, weight gain, a round face, susceptibility to infections, diabetes[] The common signs include joint stiffness, swelling, pain, redness and warmth. These are typical hallmarks of inflammation.[] It can also be difficult to diagnose because many conditions cause joint stiffness and inflammation.[]

  • Kniest Dysplasia

    Kniest dysplasia is a severe type II collagenopathy characterized by a short trunk and limbs, prominent joints and midface hypoplasia (round face with a flat nasal root).[] This is often true for spinal deformities such as scoliosis, hip conditions, knee complications and joint stiffness.[] The disease has_symptom large joints, has_symptom wide set eyes, has_symptom round flat face. ( 3 ) References: GARD:6841 MESH:C537207 OMIM:156550 Ontology: Human Disease[]

  • Arthrogryposis Multiplex Congenita

    Round face with capillary hemangioma and slightly small jaw.[] Arthrogryposis multiplex congenita (AMC) is a complex disorder that leads to joint stiffness and deformities in 2 or more joints in afflicted children.[] The face is round (although asymmetry is common) and often associated with a frontal midline capillary hemangioma, flat nasal bridge, and mild micrognathia.[]

  • Systemic Lupus Erythematosus

    Depending on the dosage, people who require steroids may develop Cushing's syndrome, symptoms of which may include obesity, puffy round face, diabetes mellitus, increased[] But, in general, lupus signs and symptoms may include: Fatigue Fever Weight loss or gain Joint pain, stiffness and swelling Butterfly-shaped rash (malar rash) on the face[] People with lupus may develop a rash, such as: A rash resembling a butterfly that appears across the nose and cheeks (malar rash) A red rash consisting of round or oval-shaped[]

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