Generalized lipodystrophy is a disorder characterized by loss of adipose tissue and, usually, metabolic disturbance due to deficiency of hormones derived from these tissues, most importantly leptin. Generalized lipodystrophy (GL) may be divided in congenital GL, also known as Berardinelli-Seip syndrome and acquired GL,…
Lipodystrophy is a disorder characterized by atrophy of adipose tissue. Lipodystrophy may be localized, partial, or total, depending on the location and degree of fat loss.
Localized lipodystrophy is usually manifested in the form of isolated or multiple, indentations, particularly in the extremities of the body in…
Familial partial lipodystrophy is a rare genetic disorder in which progressive loss of subcutaneous fat starts around puberty. Depending on the subtype, loss of fat in the extremities and trunk, with the accumulation of adipose tissue in the head and neck region may be seen. Laboratory tests and imaging studies…
Pharyngitis is defined as an infection or inflammation of the pharynx which is common in children.
Symptoms usually vary depending on whether it is a viral or bacterial infection. They may also vary from mild to severe. In case of viral pharyngitis, the symptoms include the following: Sore throat Redness of eye Cough…
Infectious mononucleosis is a common viral infection known to cause pharyngitis and fever. It is primarily an infection of teenagers and young adults caused by the Epstein Barr virus.
The majority of patients with infectious mononucleosis have mild symptoms. However a few will complain of the following features: Once…
Mucopolysaccharidosis type II (MPS 2), also known as Hunter syndrome, is a rare X-linked recessive disorder caused by deficiency of the lysosomal enzyme iduronate sulfatase.
Mucopolysaccharidosis 2 presents with a progressive multisystem involvement due to glycosaminoglycan accumulation in virtually all tissues and…
Allergic rhinitis is an inflammation of the nasal membranes that presents with any of nasal congestion, itching, sneezing and rhinorrhea or a combination of any or all of them.
Symptoms associated with this condition include pruritus of the nose or palate, rhinorrhea, sneezing, postnasal drip, nasal congestion, anosmia,…
Chronic tonsillitis is defined as more than five attacks of typical throat infection related symptoms per year accompanied by hypertrophy of the tonsils, most frequently caused by bacterial pathogens. The diagnosis can be made by physical examination and microbiological studies.
The condition associated with the…
Atopy or atopic syndrome refers to the genetic predisposition to develop hypersensitivity reactions to allergens. Atopy is characterized by allergic rhinitis, asthma, and atopic dermatitis.
Allergic shiners or dark circles under the eyes and nasal crease across the lower half of the bridge are very common features…