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1,573 Possible Causes for Lack of Developmental Milestones, Mild Cognitive Impairment, Mutation in the VPS53 Gene

  • Pontocerebellar Hypoplasia Type 2E

    cognitive impairment were present.[pesquisa.bvsalud.org] The disease, which the researchers have called PCCA2 (Progressive Cerebello-Cerebral Atrophy Type 2), is caused by two mutations in the VPS53 gene.[sciencedaily.com] In the case of PCCA, the families that have it may have one of two mutations in one gene called SepSecS, or one mutation in an unrelated gene, called VPS53.[popsci.com]

  • Hyperpyrexia

    […] of expected normal physiological development Excludes: delayed puberty ( E30.0 ) R62.0 Delayed milestone Delayed attainment of expected physiological developmental stage[apps.who.int] Late: · talker · walker R62.8 Other lack of expected normal physiological development Failure to: · gain weight · thrive Infantilism NOS Lack of growth Physical retardation[apps.who.int] Fluid retention NOS R61 Hyperhidrosis R61.0 Localized hyperhidrosis R61.1 Generalized hyperhidrosis R61.9 Hyperhidrosis, unspecified Excessive sweating Night sweats R62 Lack[apps.who.int]

    Missing: Mutation in the VPS53 Gene
  • Acute Alcohol Intoxication

    Acute alcohol intoxication refers to the development of severe and possibly life-threatening complications after ingestion of large amounts of alcohol. Symptoms range from changes in behavior to severe hypothermia, vomiting, altered consciousness, coma, and respiratory insufficiency that may be fatal. A detailed[…][symptoma.com]

    Missing: Lack of Developmental Milestones Mutation in the VPS53 Gene
  • Hypoglycemia

    Some diabetes medications increase the risk of hypoglycemia, as can inadequate nutrition, cognitive impairment, and other factors.[ncbi.nlm.nih.gov] Abstract Hypoglycemic events range from mild to severe and occur at an increased rate among older adults with diabetes.[ncbi.nlm.nih.gov]

    Missing: Lack of Developmental Milestones Mutation in the VPS53 Gene
  • Alzheimer Disease

    The first cohort included 49 older controls and 48 individuals with mild cognitive impairment, while the second cohort included 94 older controls and 57 mild cognitive impairment[ncbi.nlm.nih.gov] Recent research has identified a transitional state between the cognitive changes of normal aging and Alzheimer's disease (AD), known as mild cognitive impairment (MCI).[ncbi.nlm.nih.gov] Mild cognitive impairment (MCI) manifests as memory impairment in the absence of dementia and progresses to Alzheimer's disease (AD) at a rate of around 15% per annum, versus[ncbi.nlm.nih.gov]

    Missing: Lack of Developmental Milestones Mutation in the VPS53 Gene
  • Substance Abuse Problems

    Abstract Hospital-wide rumors and anecdotal reports had suggested that there was a potentially serious problem of alcohol and drug abuse among the psychiatric patients of this hospital. The authors describe a systematic, evaluative approach which gave direct and detailed information on the nature and extent of[…][ncbi.nlm.nih.gov]

    Missing: Lack of Developmental Milestones Mutation in the VPS53 Gene
  • Chronic Alcoholism

    […] associated impairment in emotional processes and social cognition.[ncbi.nlm.nih.gov] After some six months of abstinence, the mild cortical atrophy and impaired cognition often associated with alcoholism disappear.[britannica.com] Chronic excessive alcohol consumption is associated with cognitive deficits, ranging from mild to severe, in executive functions, memory, and metacognitive abilities, with[ncbi.nlm.nih.gov]

    Missing: Lack of Developmental Milestones Mutation in the VPS53 Gene
  • Hyponatremia

    Abstract Hyponatremia is the most common electrolyte disorder and also a predictor of mild cognition impairment.[ncbi.nlm.nih.gov] cognition impairment.[journals.plos.org] OBJECTIVE: The study objective was to determine the eventual consequences (falls, unsteadiness, and cognitive impairment) of mild chronic hyponatremia, which is generally[ncbi.nlm.nih.gov]

    Missing: Lack of Developmental Milestones Mutation in the VPS53 Gene
  • Brain Concussion

    […] an earlier age of onset in people with mild cognitive impairment and Alzheimer’s disease.[alz.org] Cognitive impairment following closed head injury. Neurol Clin. 1992 Nov. 10(4):879-93. [Medline]. McCrea M, Guskiewicz KM, Marshall SW, et al.[emedicine.medscape.com] These results were consistent with other studies that indicate traumatic brain injury is a significant risk factor for cognitive decline in older adults and associated with[alz.org]

    Missing: Lack of Developmental Milestones Mutation in the VPS53 Gene
  • Chronic Fatigue Syndrome

    ., CHF5074 reduces biomarkers of neuroinflammation in patients with mild cognitive impairment: A 12-week, double-blind, placebo-controlled study. Curr.[ncbi.nlm.nih.gov] cognitive impairment ( 39 ) and Alzheimer’s disease ( 40 ).[dx.doi.org] […] maturation and isotype switching ( 37 ); however, abnormally high levels have been associated in some studies with risk of adverse neurovascular events ( 38 ) as well as mild[dx.doi.org]

    Missing: Lack of Developmental Milestones Mutation in the VPS53 Gene