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16 Possible Causes for Lacrimal Gland Enlargement, Lymphocytes Increased, T-Lymphocyte Count Increased

  • Infectious Mononucleosis

    The levels of liver enzymes and atypical lymphocytes increase with age.[ncbi.nlm.nih.gov] The percentage of CD8 /CD11b- cells was not increased in the atypical lymphocytes. However, CD45RO was expressed on 86.3% of CD4 atypical lymphocytes.[ncbi.nlm.nih.gov] Early in the course of the mono, blood tests may show an increase in one type of white blood cell (lymphocyte).[rxlist.com]

  • Precursor-Cell Lymphoblastic Leukemia

    The increase in the ALC was primarily from activated CTL019 T lymphocytes. Patient 1 was a 7-year-old girl with a second recurrence of ALL.[doi.org] A general increase in the number of lymphocytes is known as lymphocytosis, whereas a decrease is known as lymphocytopenia.[en.wikipedia.org] Medical Definition of acute lymphoblastic leukemia : lymphocytic leukemia that is marked by an abnormal increase in the number of lymphoblasts, that is characterized by rapid[merriam-webster.com]

  • Influenza

    Deterioration of CD4 T-lymphocyte cell counts or progression of HIV disease has not been demonstrated among HIV-infected persons after influenza vaccination compared with[cdc.gov] A low absolute lymphocyte count on admission is associated with more severe disease and death.[ncbi.nlm.nih.gov] Deterioration of CD4 T-lymphocyte cell counts or progression of HIV disease have not been demonstrated among HIV-infected persons after influenza vaccination compared with[cdc.gov]

  • Acute Lymphoblastic Leukemia 

    People who have a sibling, including a twin, with acute lymphocytic leukemia have an increased risk of ALL.[mayoclinic.org] , or T lymphocytes that are not able to fight infection very well.[aacrfoundation.org] Acute lymphocytic leukemia (ALL) is a cancer of the blood and bone marrow. In ALL, there’s an increase in a type of white blood cell (WBC) known as a lymphocyte.[healthline.com]

  • Waldenstrom Macroglobulinemia

    Additional tests that may be done include: 24-hour urine protein Total protein Immunofixation in urine T (thymus derived) lymphocyte count Bone x-rays Some people with WM[nlm.nih.gov] As the numbers of abnormal lymphocytes increase, the spleen and lymph nodes “glands” will enlarge.[leukaemia.org.au] In her bone marrow, increased small lymphocytes were admixed with plasmacytoid lymphocytes and plasma cells. She was diagnosed as having lymphoplasmacytic variant of WM.[ncbi.nlm.nih.gov]

  • Herpes Zoster

    Most studies have documented increasing zoster risk as CD4 T-lymphocyte counts decline, but the risk is increased nine-fold even among HIV-infected women with CD4 T-lymphocyte[web.archive.org] Fludarabine is a purine analog that has long been incorporated in chemotherapy regimens for CLL and has been known to cause lymphocyte depletion and increased risk of viral[bloodjournal.org] Lymphocyte responses to varicella zoster virus in the elderly. J Clin Immunol. 1987;7:174–178. [PubMed] [Google Scholar] 3.[ncbi.nlm.nih.gov]

  • Mikulicz Disease

    It has features of an allergic disorder: abnormally high Th2 cytokines in tissues, raised IgE and increased T-reg lymphocytes in the blood, and raised eosinophil count in[dermnetnz.org] Mikulicz disease comprises the triad of: symmetrical enlargement of all salivary glands narrowing of the palpebral fissures due to enlargement of the lacrimal glands parchment-like[gpnotebook.co.uk] […] stimulation in IgG4-RD may increase the risk of lymphoma development.[synapse.koreamed.org]

  • Chronic Thyroiditis

    It has features of an allergic disorder: abnormally high Th2 cytokines in tissues, raised IgE and increased T-reg lymphocytes in the blood, and raised eosinophil count in[dermnetnz.org] Lacrimal gland enlargement was observed in 8 cases.[ajnr.org] Variable Variable Present Subacute granulomatous Viral Yes Decreased Decreased Increased Absent Subacute lymphocytic Autoimmune No Decreased Decreased Increased Present Microbial[aafp.org]

  • IgG4-Related Retroperitoneal Fibrosis

    It has features of an allergic disorder: abnormally high Th2 cytokines in tissues, raised IgE and increased T-reg lymphocytes in the blood, and raised eosinophil count in[dermnetnz.org] Most commonly involved are the pancreas, major salivary glands (sialadenitis, salivary gland enlargement), lacrimal glands (lacrimal gland enlargement and proptosis), retroperitoneal[elynsgroup.com] Exclusive increase of CX3CR1 CD28-CD4 T cells in inflammatory bowel disease and their recruitment as intraepithelial lymphocytes.[ncbi.nlm.nih.gov]

  • IgG4-Related Ophthalmic Disease

    It has features of an allergic disorder: abnormally high Th2 cytokines in tissues, raised IgE and increased T-reg lymphocytes in the blood, and raised eosinophil count in[dermnetnz.org] Role of Th2 cells in IgG4-related lacrimal gland enlargement. Int Arch Allergy Immunol 2010;152(Suppl. 1):47-53. Yamada K, Kawano M, Inoue R et al.[eyewiki.aao.org] Fig. 3 a, b Transsphenoidal biopsy of the skull base mass demonstrating an inflammatory infiltrate with lymphocytes and slight increase in B cells with interspersed macrophages[joii-journal.springeropen.com]

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