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3,265 Possible Causes for Lacrimal Gland Enlargement, Splenomegaly, T-Lymphocyte Count Increased

  • Infectious Mononucleosis

    Clinical estimates of splenomegaly are fallible.[ncbi.nlm.nih.gov] In adolescent and adult patients presenting with sore throat, the presence of posterior cervical, inguinal or axillary adenopathy, palatine petechiae, splenomegaly, or atypical[ncbi.nlm.nih.gov] Abdominal ultrasound may be required to assess for splenomegaly.[patient.info]

  • Precursor-Cell Lymphoblastic Leukemia

    The increase in the ALC was primarily from activated CTL019 T lymphocytes. Patient 1 was a 7-year-old girl with a second recurrence of ALL.[doi.org] Splenomegaly and thrombocytopenia were frequently observed more in CD200 patients. Increased frequency of CD34 was associated with CD200 and CD56 patients.[ncbi.nlm.nih.gov] Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[doi.org]

  • Acute Lymphoblastic Leukemia 

    Surgical consults could also be included in the plan of care for patients with severe splenomegaly and/or bulky/painful lymphadenopathy.[cancertherapyadvisor.com] […] had some significance with certain treatment regimens, are the percentage of circulating blast cells; the degree of bone marrow involvement; the presence of hepatomegaly, splenomegaly[cancernetwork.com] Abdominal distention due to hepatomegaly and splenomegaly. Lymphadenopathy. Testicular enlargement. Gum hypertrophy. Leukaemia cutis [ 9 ].[patient.info]

  • Waldenstrom Macroglobulinemia

    Additional tests that may be done include: 24-hour urine protein Total protein Immunofixation in urine T (thymus derived) lymphocyte count Bone x-rays Some people with WM[nlm.nih.gov] The presence of progressive, symptomatic lymphadenopathy or splenomegaly provide additional reasons to begin therapy. The presence of anemia with a hemoglobin value of[ncbi.nlm.nih.gov] Abstract Manifestations of macroglobulinemic lymphoma include lymphadenopathy, splenomegaly and bone marrow involvement.[ncbi.nlm.nih.gov]

  • Non-Hodgkin Lymphoma

    Computed tomography scan of the chest and abdomen showed paratracheal and subcarinal lymphadenopathy and splenomegaly, with the findings being compatible with lymphoma.[ncbi.nlm.nih.gov] Splenomegaly. Hepatomegaly. Intermediate- and high-grade lymphomas: Most patients present with rapidly growing and bulky lymphadenopathy.[patient.info] Splenomegaly is observed in approximately 40% of patients; the spleen is rarely the only involved site at presentation.[emedicine.medscape.com]

    Missing: T-Lymphocyte Count Increased
  • Hepatitis

    Dehydration with drying of mucous membranes Telangiectasis (spider angiomata) and esophageal varices Jaundice Ascites Utricarial rashes Portal Hypertension Hepatomegaly and Splenomegaly[symptoma.com] Mild splenomegaly occurs in 15 to 20% of patients. Jaundice usually peaks within 1 to 2 wk. Recovery phase: During this 2- to 4-wk period, jaundice fades.[merckmanuals.com] Physical examination may be without pathological findings, but may also reveal hepatomegaly, splenomegaly, jaundice, and signs and symptoms of chronic liver disease[ 1 9 ][doi.org]

    Missing: Lacrimal Gland Enlargement
  • Primary Immune Deficiency Disorder

    Splenomegaly and generalized lymphadenopathy are present in many patients with common variable immunodeficiency (CVID).[emedicine.medscape.com] Skin infections become more common as the number of CD4 T- lymphocytes reduces. Mild reduction in CD4 T- lymphocyte count ( 200) is part of normal ageing.[dermnetnz.org] Hepatomegaly and splenomegaly may be detected in the abdomen. In infants, crusting around the anus may be a sign of chronic diarrhoea.[patient.info]

    Missing: Lacrimal Gland Enlargement
  • Lymphoma

    Lacrimal gland. The enlarged gland displaces the eyeball inferomedially. Eyelids. Swelling and prolapse may occur in the eyelid.[aao.org] At diagnosis, patients usually present with adenopathy and, in 50% of cases, splenomegaly.[orpha.net] However, the presence of extensive retroperitoneal lymphadenopathy and splenomegaly favours lymphoma, whereas adjacent fat infiltration supports adenocarcinoma.[radiopaedia.org]

    Missing: T-Lymphocyte Count Increased
  • Sarcoidosis

    […] conjunctival nodules, lacrimal gland enlargement, cataracts, glaucoma, retinal ischaemia, optic neuropathy, and papillo-oedema. w6 Hepatic or gastrointestinal (18%) —Typically[doi.org] In this report, we describe the case of a 12-year-old girl presenting with fatigue and weight loss, with a painless hepato-splenomegaly without additional clinical signs on[ncbi.nlm.nih.gov] The indications of splenectomy include abdominal pain due to splenomegaly, hypersplenism, functional asplenia or spontaneous splenic rupture(6).[pneumologia.eu]

    Missing: T-Lymphocyte Count Increased
  • Leukemia

    Five features were present in 50% of children: hepatomegaly (64%), splenomegaly (61%), pallor (54%), fever (53%) and bruising (52%).[ncbi.nlm.nih.gov] Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly.[icd9data.com] […] leukemia (T-PLL) is the most common type of mature T-cell leukemia and is characterized by a rapidly rising peripheral blood lymphocyte count, bone marrow involvement, and splenomegaly[web.archive.org]

    Missing: T-Lymphocyte Count Increased

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