Lacrimal gland absence or hypoplasia causes symptoms such as irritable eyes, recurrent eye infections and epiphora.
ALSG has variable expressivity, and affected individuals may have aplasia or hypoplasia of the lacrimal, parotid, submandibular, and sublingual glands and absence of the lacrimal
LADD syndrome is caused by FGF10 mutations and is allelic to autosomal dominant Aplasia/Hypoplasia of Lacrimal and Salivary Glands. J.M. Milunsky 1,2,3, G. Zhao 1, T.A.