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73 Possible Causes for Lactate Dehydrogenase Increased, Leg Cramp, Muscle Tenderness

  • Acute Exertional Rhabdomyolysis

    Delayed onset muscle soreness (DOMS), creatine kinase (CK) and lactate dehydrogenase (LDH) activity, total leukocyte counts, interleukin-6 and C-reactive protein (CRP) were[] […] first, ASCENDING hyporeflexia and areflexia can have autonomic dysfcn and opthalmoparesis sensory changes less prominent may have pain- arthralgias and back pain, cramping[] Patients may have muscle weakness, cramping, stiffness and tenderness on palpation to muscles during physical exam.[]

  • Rhabdomyolysis

    […] creatine phosphokinase, myoglobin, lactate dehydrogenase, serum aspartate aminotransferase, hypercholesterolemia, and a basal serum prolactin near the upper limit of normal[] The patient presented with muscle tenderness over the lower limbs and dark brown-to-red colored urine.[] CASE REPORT A 72-year-old patient presented to our Emergency Department with typical signs of rhabdomyolysis consisting of muscular cramps and pain in both legs and a significant[]

  • Myopathy

    The laboratory evaluation was remarkable for the marked increase in the serum lactate dehydrogenase and creatine phosphokinase levels.[] Other symptoms of myopathy can include include muscle cramps, stiffness, and spasm.[] […] weakness, impaired function in activities of daily life, and, rarely, muscle pain and tenderness.[]

  • Pulmonary Embolism

    Sitting in a cramped position during lengthy plane or car trips slows blood flow in the legs, which contributes to the formation of clots. Other risk factors Smoking.[] There may be symptoms of a DVT, such as pain at the back of the calf in the leg, tenderness of the calf muscles or swelling of a leg or foot.[] An extremity with a DVT is unlikely to lose pulses, but patients may have nonspecific leg pain and tenderness (particularly in the calf muscles) and increased warmth and swelling[]

  • Amyotrophic Lateral Sclerosis

    For example, NSC-34 cells treated with CSF from patients with ALS exhibited decreased cell viability and increased lactate dehydrogenase activity [ 48 ], suggesting that factors[] A Cochrane review explored the interventions for leg cramps in pregnancy ( Young 2002 ).[] Weak muscles may ache and are occasionally tender. Proximal muscles are more affected than distal muscles; lower extremity muscles are affected predominantly.[]

  • Portal Cirrhosis

    Digestive issues like nausea, vomiting, abdominal pain and cramping.[] […] pain or tenderness, red and blotchy patches on the skin, and blood capillaries on the upper abdomen.[] Symptoms of PBC in its early stages include fatigue, itchy skin, and dry eyes and mouth. swelling of the legs, ankles, feet (oedema).[]

  • Pernicious Anemia

    […] tongue Weak muscles The symptoms of megaloblastic anemia may resemble other blood conditions or medical problems.[] Symptoms that affect the gastrointestinal system include a sore and brightly red tongue, loss of appetite, weight loss, diarrhea, and abdominal cramping.[] […] tongue weak muscles (Vitamin B12 specific) Lightheadedness upon standing or exertion Difficulty concentrating Shortness of breath (primarily during exercise) Swollen, red[]

  • Progressive Muscular Atrophy

    Males with Kennedy's disease have shaking hands, muscle cramps and twitches, and weakness in their face, arms, and legs. They may have trouble swallowing and speaking.[] Multiple neuritis is distinguished by the rapid onset, the wide extent of the parts affected, the numbness of anesthesia, and the tenderness of the muscles.[] Weakness may progress more on one side of the body than on the other and usually proceeds up the arm or leg.[]

  • Glycogen Storage Disease Type 7

    The incresased levels of pyruvate lead to increased lactate produciton via lactate dehydrogenase (LDH) and alanine via alanine transaminase (ALT).[] Arms Fatigue Cramps: Proximal muscles Muscle size Atrophy: Proportionate to weakness May be mild calf hypertrophy Tendon reflexes: Reduced in proportion to weakness Cardiac[] The body breaks down muscle when trying to attain energy, which causes many symptoms such as muscle pain, muscle cramping, muscle fatigue, and muscle tenderness.[]

  • Myxedema

    Elevated lactate dehydrogenase concentrations, acidosis, and anemia are common findings. Lumbar puncture reveals increased opening pressure and high protein content.[] […] of hair Carpal Tunnel Syndrome In the later stages, suffering individuals typically display other discomforting signs like: Weight gain Slow speech Pale skin Swelling of leg[] […] cholesterol level Muscle aches, tenderness and stiffness Pain, stiffness or swelling in your joints Heavier than normal or irregular menstrual periods Thinning hair Slowed[]

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