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73 Possible Causes for Lactate Dehydrogenase Increased, Leg Cramp, Muscle Tenderness

  • Acute Exertional Rhabdomyolysis

    Delayed onset muscle soreness (DOMS), creatine kinase (CK) and lactate dehydrogenase (LDH) activity, total leukocyte counts, interleukin-6 and C-reactive protein (CRP) were[docplayer.net] […] first, ASCENDING hyporeflexia and areflexia can have autonomic dysfcn and opthalmoparesis sensory changes less prominent may have pain- arthralgias and back pain, cramping[quizlet.com] Patients may have muscle weakness, cramping, stiffness and tenderness on palpation to muscles during physical exam.[emdocs.net]

  • Rhabdomyolysis

    […] creatine phosphokinase, myoglobin, lactate dehydrogenase, serum aspartate aminotransferase, hypercholesterolemia, and a basal serum prolactin near the upper limit of normal[ncbi.nlm.nih.gov] The patient presented with muscle tenderness over the lower limbs and dark brown-to-red colored urine.[ncbi.nlm.nih.gov] CASE REPORT A 72-year-old patient presented to our Emergency Department with typical signs of rhabdomyolysis consisting of muscular cramps and pain in both legs and a significant[ncbi.nlm.nih.gov]

  • Myopathy

    The laboratory evaluation was remarkable for the marked increase in the serum lactate dehydrogenase and creatine phosphokinase levels.[ncbi.nlm.nih.gov] Other symptoms of myopathy can include include muscle cramps, stiffness, and spasm.[ninds.nih.gov] […] weakness, impaired function in activities of daily life, and, rarely, muscle pain and tenderness.[emedicine.com]

  • Pulmonary Embolism

    Sitting in a cramped position during lengthy plane or car trips slows blood flow in the legs, which contributes to the formation of clots. Other risk factors Smoking.[mayoclinic.org] There may be symptoms of a DVT, such as pain at the back of the calf in the leg, tenderness of the calf muscles or swelling of a leg or foot.[patient.info] An extremity with a DVT is unlikely to lose pulses, but patients may have nonspecific leg pain and tenderness (particularly in the calf muscles) and increased warmth and swelling[emsworld.com]

  • Amyotrophic Lateral Sclerosis

    For example, NSC-34 cells treated with CSF from patients with ALS exhibited decreased cell viability and increased lactate dehydrogenase activity [ 48 ], suggesting that factors[doi.org] A Cochrane review explored the interventions for leg cramps in pregnancy ( Young 2002 ).[doi.org] Weak muscles may ache and are occasionally tender. Proximal muscles are more affected than distal muscles; lower extremity muscles are affected predominantly.[web.archive.org]

  • Portal Cirrhosis

    Digestive issues like nausea, vomiting, abdominal pain and cramping.[marylandhearingcenter.com] […] pain or tenderness, red and blotchy patches on the skin, and blood capillaries on the upper abdomen.[marylandhearingcenter.com] Symptoms of PBC in its early stages include fatigue, itchy skin, and dry eyes and mouth. swelling of the legs, ankles, feet (oedema).[marylandhearingcenter.com]

  • Pernicious Anemia

    […] tongue Weak muscles The symptoms of megaloblastic anemia may resemble other blood conditions or medical problems.[stanfordchildrens.org] Symptoms that affect the gastrointestinal system include a sore and brightly red tongue, loss of appetite, weight loss, diarrhea, and abdominal cramping.[encyclopedia.com] […] tongue weak muscles (Vitamin B12 specific) Lightheadedness upon standing or exertion Difficulty concentrating Shortness of breath (primarily during exercise) Swollen, red[danafarberbostonchildrens.org]

  • Progressive Muscular Atrophy

    Males with Kennedy's disease have shaking hands, muscle cramps and twitches, and weakness in their face, arms, and legs. They may have trouble swallowing and speaking.[webmd.com] Multiple neuritis is distinguished by the rapid onset, the wide extent of the parts affected, the numbness of anesthesia, and the tenderness of the muscles.[henriettes-herb.com] Weakness may progress more on one side of the body than on the other and usually proceeds up the arm or leg.[merckmanuals.com]

  • Glycogen Storage Disease Type 7

    The incresased levels of pyruvate lead to increased lactate produciton via lactate dehydrogenase (LDH) and alanine via alanine transaminase (ALT).[themedicalbiochemistrypage.org] Arms Fatigue Cramps: Proximal muscles Muscle size Atrophy: Proportionate to weakness May be mild calf hypertrophy Tendon reflexes: Reduced in proportion to weakness Cardiac[neuromuscular.wustl.edu] The body breaks down muscle when trying to attain energy, which causes many symptoms such as muscle pain, muscle cramping, muscle fatigue, and muscle tenderness.[agsdus.org]

  • Myxedema

    Elevated lactate dehydrogenase concentrations, acidosis, and anemia are common findings. Lumbar puncture reveals increased opening pressure and high protein content.[endocrinologyadvisor.com] […] of hair Carpal Tunnel Syndrome In the later stages, suffering individuals typically display other discomforting signs like: Weight gain Slow speech Pale skin Swelling of leg[hxbenefit.com] […] cholesterol level Muscle aches, tenderness and stiffness Pain, stiffness or swelling in your joints Heavier than normal or irregular menstrual periods Thinning hair Slowed[mayoclinic.org]

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