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1,021 Possible Causes for Lactate Dehydrogenase Increased, Leukocyte Alkaline Phosphatase Increased, Wide Space Between the First and Second Toe

  • Non-Hodgkin Lymphoma

    Most of the aggressive lymphomas present with a rapidly growing tumor mass, fever, night sweats, weight loss, and increased levels of serum lactate dehydrogenase and uric[symptoma.com] One indicator of the potential for tumor lysis syndrome is an elevated plasma lactate dehydrogenase level or hyperuricemia at the time of diagnosis.[emedicine.medscape.com] The start of effective chemotherapy acutely increases the risk of complications, including hyperkalemia, hyperphosphatemia, hypocalcemia, oliguria, and renal failure.[emedicine.medscape.com]

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  • Hepatocellular Carcinoma

    dehydrogenase, inhibited cell migration, and enhanced the apoptosis rate in HepG2 and PLC/PRF/5 cells. 5h2c led to an increase in intracellular reactive oxygen species levels[ncbi.nlm.nih.gov] […] a screened synthesis compound, against hepatocellular carcinoma (HCC) in both in vitro and in vivo models. 5h2c strongly decreased cell viability, caused over-release of lactate[ncbi.nlm.nih.gov]

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  • Portal Cirrhosis

    Laennec's cirrhosis, also known as portal cirrhosis, alcoholic cirrhosis, fatty cirrhosis, or atrophic cirrhosis, [1] is named after René Laennec, [2] a French physician and the inventor of the stethoscope. It is a disease of the liver in which the normal lobular architecture is lost, with fibrosis (scarring) and later[…][en.wikipedia.org]

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  • Primary Myelofibrosis

    The latter was associated more frequently with anaemia, thrombocytopenia, peripheral blood blasts and increased lactate dehydrogenase levels.[ncbi.nlm.nih.gov] alkaline phosphatase (LAP) score is increased Treatment Reduced intensity allogeneic stem cell transplant if intermediate to high risk or palliation of extramedullary hematopoiesis[pathologyoutlines.com] Lactate Dehydrogenase (LDH) Anemia Splenomegaly What Other Diseases Should Be Considered and How Do I Distinguish Between Them?[clinicaladvisor.com]

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  • Viral Hepatitis

    Lactate dehydrogenase (LD) – an enzyme released with cell damage; found in cells throughout the body.[labtestsonline.org] The GGT test helps to differentiate between the causes of an elevated ALP; if GGT is increased, then the elevated ALP is due to liver, not bone disease.[labtestsonline.org]

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  • Macronodular Cirrhosis

    OBJECTIVE: Patients with hepatocellular carcinoma (HCC) presenting with nonmicronodular or micronodular cirrhosis are usually treated by hepatectomy. The value of resection for patients with hepatitis B virus-related macronodular cirrhosis, however, remains unknown because of potentially fatal complications of this[…][ncbi.nlm.nih.gov]

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  • Cholestasis

    Toxicol Lett. 2018 Oct 1;295:187-194. doi: 10.1016/j.toxlet.2018.06.1069. Epub 2018 Jun 18. Author information 1 KaLy-Cell, 20A rue du Général Leclerc, 67115 Plobsheim, France. 2 Department of Physiology and Pharmacology, Section of Pharmacogenetics, Karolinska Institutet, Stockholm, Sweden. 3 Hôpital Jean Minjoz, 3 Boulevard[…][ncbi.nlm.nih.gov]

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  • Multiple Myeloma

    Also, reflecting this aggressive clinical presentation, a higher proportion of patients with pPCL have significant leukocytosis, elevated lactate dehydrogenase (LDH) and β2[doi.org] In fact, patients with MM usually show normal or moderately increased LDH serum levels, with a significant LDH elevation only observed in patients with high tumor load (43%[doi.org]

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  • Chronic Lymphocytic Leukemia

    […] chemicals measured in blood tests , for example lactate dehydrogenase (LDH) or calcium.[lymphoma-action.org.uk] The upper limit of the normal range (ULN) for the lactate dehydrogenase level was 250 U per liter.[nejm.org] These include: fast growing lymph nodes or masses in your body a change in your symptoms, for example B symptoms (weight loss, night sweats, fevers) an increase in certain[lymphoma-action.org.uk]

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  • Liver Failure

    Abstract Acute-on-chronic liver failure (ACLF) is characterized by organ failure mediated by acute decompensation of cirrhosis. Recent studies have highlighted the importance of the gut-liver axis (GLS) and its association with ACLF pathogenesis. In this review, we discuss the mechanisms related to the alteration[…][ncbi.nlm.nih.gov]

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