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310 Possible Causes for Lactate Dehydrogenase Increased, Leukopenia, Thrombocytopenia

  • Infectious Mononucleosis

    They include Granulocytopenia Thrombocytopenia Hemolytic anemia Transient mild granulocytopenia or thrombocytopenia occurs in about 50% of patients; severe cases, associated[merck.com] Leukopenia and thrombocytopenia are not uncommon.[ncbi.nlm.nih.gov] Corticosteroids may have a role in hastening resolution of some complications, especially upper airway obstruction and possibly immune-mediated anemia and thrombocytopenia[doi.org]

  • Paroxysmal Nocturnal Hemoglobinuria

    The effect of eculizumab on intravascular hemolysis was demonstrated by a reduction in lactate dehydrogenase levels at all measurements after baseline.[ncbi.nlm.nih.gov] The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding[ncbi.nlm.nih.gov] CBC showed leukopenia (WBC 2.9 x 103 /µL) with neutropenia (segmented neutrophils 48%), macrocytic anemia (Hgb 6.1 g/dL, hematocrit 20%, MCV,113 fL) and thrombocytopenia ([ncbi.nlm.nih.gov]

  • Hairy Cell Leukemia

    Lactate dehydrogenase (LDH) is usually normal.[clinicaladvisor.com] […] of the lymphoreticular cells which is considered to be a rare type of chronic leukemia; it is characterized by an insidious onset, splenomegaly, anemia, granulocytopenia, thrombocytopenia[icd9data.com] Later he developed leukopenia and pancytopenia. Bone marrow biopsies showed fibrosis.[ncbi.nlm.nih.gov]

  • Primary Myelofibrosis

    The latter was associated more frequently with anaemia, thrombocytopenia, peripheral blood blasts and increased lactate dehydrogenase levels.[ncbi.nlm.nih.gov] Six weeks later, he developed grade 4 thrombocytopenia and grade 3 anemia.[ncbi.nlm.nih.gov] We found that fibrosis grade 2 and greater on a 0-3 scale was associated with clinical characteristics indicative of a more advanced disease, such as anemia, leukopenia, thrombocytopenia[ncbi.nlm.nih.gov]

  • Acute Lymphoblastic Leukemia

    Serum level of lactate dehydrogenase (LDH) predicts increased anaerobic glycolysis and is associated with metabolic modulation in cancer cells.[ncbi.nlm.nih.gov] This bleeding is commonly attributed to thrombocytopenia due to bone marrow suppressive chemotherapeutic agents.[ncbi.nlm.nih.gov] CASE REPORT We report the case of a 58-year-old male patient who presented with severe chest pain, dyspnea, systemic symptoms, leukopenia, normocytic anemia, and severe lactic[ncbi.nlm.nih.gov]

  • Systemic Lupus Erythematosus

    Blood platelet counts (BPCs) of 20   10/L represent severe thrombocytopenia, and a BPC of 21 to 50   10/L indicates moderate thrombocytopenia.[ncbi.nlm.nih.gov] Drugs causing leukopenia Some drugs may lead to leukopenia.[news-medical.net] Acalculous cholecystitis and thrombocytopenia were initially suspected to be complicated with SLE and vasculitis.[ncbi.nlm.nih.gov]

  • Familial Myelofibrosis

    Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia.[symptoma.com] Thus, patients suffering from myelofibrosis eventually develop anemia, leukopenia, and thrombocytopenia.[symptoma.com]

  • Rocky Mountain Spotted Fever

    This child had no serious bleeding manifestations and minimal hemorrhagic skin manifestations despite severe RMSF, concurrent thrombocytopenia, as well as the coagulation[ncbi.nlm.nih.gov] Leukopenia, thrombocytopenia, elevated hepatic transaminase levels, and mild anemia are characteristic laboratory findings in anaplasmosis.[doi.org] The combination of fever, headache, myalgias, marked left shift in the differential white blood cell count, severe thrombocytopenia, and hyponatremia all help to suggest the[ncbi.nlm.nih.gov]

  • B-Precursor Acute Lymphoblastic Leukemia

    […] the case of a 9-year-old girl from northwestern Greece admitted to our Hospital because of malaise, low-grade fever, intermittent hip joint pain, anemia, leukopenia and thrombocytopenia[ncbi.nlm.nih.gov] The most common ( 2%) adverse reactions reported as the reason for permanent discontinuation were infection, thrombocytopenia, hyperbilirubinemia, transaminases increased,[adcreview.com] Frequently reported adverse events included thrombocytopenia, neutropenia, leukopenia, infection, anemia, hemorrhage, fatigue, fever, nausea, headache, liver damage, hyperbilirubinemia[cancertherapyadvisor.com]

  • Erythema Infectiosum

    Abstract A report is presented of a patient with neonatal erythema infectiosum who developed petechiae, transient thrombocytopenia and transient cardiac failure due to transplacental[ncbi.nlm.nih.gov] The reduction in the reticulocyte count is occasionally accompanied by leukopenia and thrombocytopenia.[aafp.org] Thrombocytopenia, leukopenia, or both may be seen in acute infection, even in immunologically normal hosts.[emedicine.com]

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