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150 Possible Causes for Lactate Dehydrogenase Increased, Muscle Cramps with Exercise

  • Glycogen Storage Disease Type 1

    The incresased levels of pyruvate lead to increased lactate produciton via lactate dehydrogenase (LDH) and alanine via alanine transaminase (ALT).[themedicalbiochemistrypage.org] The goal of treatment is to avoid muscle fatigue and/or cramps induced by exercise.[mda.org.au] Similarly, Lactate dehydrogenase (LDH) deficiency is not increased in any particular sub-population group.[cancertherapyadvisor.com]

  • Glycogen Storage Disease Type 2

    dehydrogenase are increased in most patients with PD but may occasionally be within normal limits in those with adult-onset PD. 34 Muscle biopsies for primary diagnostic[dx.doi.org] The goal of treatment is to avoid muscle fatigue and/or cramps induced by exercise.[chp.edu] Serum enzymes such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), or lactate dehydrogenase (LDH) may be elevated and may reflect enzymes released from[dx.doi.org]

  • Glycogen Storage Disease Type 7

    The incresased levels of pyruvate lead to increased lactate produciton via lactate dehydrogenase (LDH) and alanine via alanine transaminase (ALT).[themedicalbiochemistrypage.org] […] intolerance Decreased ability to exercise Inability to exercise [ more ] 0003546 Exercise-induced muscle cramps Exercise-induced muscle cramping Muscle cramps following exercise[rarediseases.info.nih.gov] […] in muscle Heterozygotes: Manifesting patients described Variant syndrome Symptoms associated with statin use: 1 patient Lactate dehydrogenase A deficiency (GSD 11) L-lactate[neuromuscular.wustl.edu]

  • Glycogen Storage Disease due to Phosphoglycerate Kinase 1 Deficiency

    The incresased levels of pyruvate lead to increased lactate produciton via lactate dehydrogenase (LDH) and alanine via alanine transaminase (ALT).[themedicalbiochemistrypage.org] Myopathy is a common finding and is characterized by exercise-intolerance, muscle weakness, cramping, myalgia and episodes of myoglobinuria.[orpha.net] Clinically, there are two distinct syndromes: A pure muscle syndrome characterized by recurrent cramps and muscle breakdown in response to intense exercise. [ 3 ] A "muscle[patient.info]

  • Acute Exertional Rhabdomyolysis

    Delayed onset muscle soreness (DOMS), creatine kinase (CK) and lactate dehydrogenase (LDH) activity, total leukocyte counts, interleukin-6 and C-reactive protein (CRP) were[docplayer.net] […] or fever-induced rhabdomyolysis or malignant hyperthermia’, and the ‘presence of exertional muscle cramps or exercise intolerance’.[bmjopensem.bmj.com] […] and muscle cramps muscle wasting may be present sensitive to maximal intensity exercise, can be notices with less intense and sustained exercise rhabdomyolysis darkly colored[quizlet.com]

  • Myopathy

    The laboratory evaluation was remarkable for the marked increase in the serum lactate dehydrogenase and creatine phosphokinase levels.[ncbi.nlm.nih.gov] These myopathies can cause progressive muscle weakness, fatigue, episodes of pain and cramps after exercise, and/or extensive death and breakdown of muscle tissue.[rheumatology.org] Negative symptoms include muscle weakness, exercise intolerance and fatigue, while so called positive symptoms usually encompass cramps and myalgias, with occasional contractures[news-medical.net]

  • Heat Stroke

    Mild elevations in aspartate aminotransferase (AST), lactate dehydrogenase (LD) and total bilirubin have been described.[bja.oxfordjournals.org] Heat edema Heat cramps - Muscle pains that happen during heavy exercise in hot weather. Heat rash - Skin irritation from excessive sweating.[en.wikipedia.org] Heat cramps - muscle pains or spasms that happen during heavy exercise. You usually get them in your abdomen, arms, or legs.[nlm.nih.gov]

  • Amyotrophic Lateral Sclerosis

    For example, NSC-34 cells treated with CSF from patients with ALS exhibited decreased cell viability and increased lactate dehydrogenase activity [ 48 ], suggesting that factors[doi.org] Some medicines, and heat or whirlpool therapy may help relieve muscle cramping. Exercise, in moderation, may help maintain muscle strength and function.[cedars-sinai.org] Important diseases that can mimic MND [ 1 ] Benign cramp fasciculation syndrome: Fasciculation or cramps usually affecting large muscles (for example, calves).[patient.info]

  • Rhabdomyolysis

    […] deficiency Other genetic causes -Phosphorylase kinase -Phosphofructokinase (Tarui’s disease) -Phosphoglycerate mutase -Phosphoglycerate kinase -Lactate dehydrogenase -Carnitine[physio-pedia.com] Physical symptoms of rhabdomyolysis might include muscle failure (during the time of exercise), muscle pain, muscle stiffness, muscle cramping, and muscle weakness.[yourlivingbody.com] Rhabdomyolysis can be confused with various typical problems reported by athletes and those involved in regular and exertional exercise such as muscle cramping, dehydration[kon.org]

  • Anemia due to Glutathione Metabolism Disorder

    Total and unconjugated bilirubin : levels are increased due to increased RBC destruction Serum lactate dehydrogenase (LDH) level : increased Serum haptoglobin level : decreased[medcaretips.com] Muscle cramps, muscle weakness, easy fatigability. Myoglobinuria with strenuous exercise.[kumc.edu] Pyruvate Dehydrogenase Deficiency Autosomal Recessive. Pyruvate Dehydrogenase deficiency ------ buildup of lactate and pyruvate ------ lactic acidosis.[kumc.edu]

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