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70 Possible Causes for Lactate Dehydrogenase Increased, Neutrophil Count Increased, Uric Acid Increased

  • Chronic Myeloid Leukemia

    […] serum lactate dehydrogenase level, anemia, and palpable splenomegaly.[doi.org] […] of 10K WBC count of 147K and platelet count of 740K Promyelocyte, myelocytes, neutrophils and 2 basophils Chronic phase - bone marrow biopsy: Hypercellular marrow with panmyeloid[pathologyoutlines.com] Gout – increased cell turnover excess purines broken down to uric acid Increased susceptibility to infections – functional immune cells Shortness of breath/fatigue – anaemia[geekymedics.com]

  • Acute Myelocytic Leukemia

    If the white blood cell count, specifically the neutrophil count, is very low, this can weaken the immune system’s functioning and make it harder for a patient to fight off[mdanderson.org] Joint Pain Joint pain occurs due to the presence of increased deposition of uric acid in the joints resulting in gout .[lecturio.com] Patients with AML often have decreased neutrophil levels despite an increased total white blood cell (WBC) count.[emedicine.medscape.com]

  • Chronic Phase of Chronic Myeloid Leukemia

    […] of 10K WBC count of 147K and platelet count of 740K Promyelocyte, myelocytes, neutrophils and 2 basophils Chronic phase - bone marrow biopsy: Hypercellular marrow with panmyeloid[pathologyoutlines.com] acid – gout/uropathy Histamine increase with basophil 90% In normal cells, two red and two green signals indicate the location of the normal ABL and BCR genes, respectively[slideshare.net] […] hyperplasia Hypercellular marrow with increased megakaryocytes; myeloid cells are primarily neutrophils PAS stain - left: perivascular accentuation of promyelocytes; right[pathologyoutlines.com]

  • Autoimmune Hemolytic Anemia

    Unconjugated bilirubin is usually, but not always, elevated and urine urobilinogen is increased. Lactate dehydrogenase is usually elevated into the thousands.[clinlabnavigator.com] Increased serum unconjugated bilirubin, increased lactate dehydrogenase (LDH) and reduced or absent haptoglobin. Increased urinary urobilinogen, haemosiderinuria.[patient.info]

  • Sickle Cell Disease

    During hydroxyurea treatment, the white-cell count, absolute neutrophil count, and absolute reticulocyte count significantly decreased, reflecting the intended mild bone marrow[doi.org] […] fetal hemoglobin (HbF) concentration while hemolysis was diminished and neutrophil counts fell. 3, 4 In SCA, HbF levels are inversely related to mortality. 1 Decreased morbidity[dx.doi.org] Expected significant increases were observed in both the hemoglobin and fetal hemoglobin levels, along with significant decreases in the absolute neutrophil and reticulocyte[doi.org]

  • Hodgkin Lymphoma

    The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a[…][ncbi.nlm.nih.gov]

  • Non-Hodgkin Lymphoma

    Most of the aggressive lymphomas present with a rapidly growing tumor mass, fever, night sweats, weight loss, and increased levels of serum lactate dehydrogenase and uric[symptoma.com] During the hospitalization his pleural fluid became purulent and changes in blood counts were registered with the increase of leukocytes, especially neutrophils.[ncbi.nlm.nih.gov] One indicator of the potential for tumor lysis syndrome is an elevated plasma lactate dehydrogenase level or hyperuricemia at the time of diagnosis.[emedicine.medscape.com]

  • Leukemia

    HCL, and second by increasing the neutrophil count before the administration of cladribine it would potentially have a favorable impact on nadir neutrophil counts.[bloodjournal.hematologylibrary.org] acid. 21 Immunosuppression from chemotherapy, hematopoietic stem cell transplantation, or the leukemia itself may increase the risk of serious infections.[aafp.org] ; increased or unexplained bleeding or bruising, due to a very low platelet count.[leukaemia.org.au]

  • Myeloproliferative Disease

    Proposed revised WHO criteria for primary myelofibrosis: Minor criteria:  Leukoerythroblastosis  Increase in serum lactate dehydrogenase level  Anemia  Palpable splenomegaly[slideshare.net] Main feature: gradual increase in leukocyte count See too many neutrophils at various stages of maturation, granulocytosis with all granulocytic precursors, and there is characteristic[quizlet.com] Furthermore, ruxolitinib also decreased plasma levels of N-terminal pro-brain natriuretic peptide, von Willebrand antigen, ristocetin-cofactor activity and uric acid, and[err.ersjournals.com]

  • Polycythemia Vera

    Additional studies have found that increased serum lactate dehydrogenase, increased leukocytosis and male gender are risks for myelofibrotic transformation. 16, 30, 33 Table[nature.com] […] platelet count, an abnormally increased neutrophil count, radiological evidence of splenomegaly, and abnormally low serum erythropoietin.[patient.info] Increased uric acid Presence of the JAK2 mutation Hypercellular bone marrow 5.[slideshare.net]

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