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45 Possible Causes for Lactate Dehydrogenase Increased, Red Blood Cell Distribution Width Increased

  • Iron Deficiency Anemia

    […] high red blood cell distribution width, reflecting an increased variability in the size of red blood cells.A low mean corpuscular volume also appears during the course of[en.wikipedia.org] This is reflected in the red blood cell distribution width (RDW); thus, the earliest evidence of the development of an iron-deficient erythropoiesis is seen in the peripheral[emedicine.medscape.com] If the anemia is due to iron deficiency, one of the first abnormal values to be noted on a complete blood count, as the body's iron stores begin to be depleted, will be a[en.wikipedia.org]

  • Thalassemia

    At the end of the treatment period, Hb and HbF increased by 2.5   1.8 g/dL and 2.5   1.6 g/dL, while bilirubin, lactate dehydrogenase, and the nucleated red blood cell count[ncbi.nlm.nih.gov] blood cell distribution width High Normal; occasionally high Normal Ferritin Low Normal Normal Mentzer index for children (MCV/red blood cell count) 13 13 13 Hb electrophoresis[aafp.org] Though some overlap with α-thalassemia carrier states exists, individuals with iron deficiency anemia show a marked increase in red blood cell distribution width (RDW), a[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    Sickle cell disease is the name for a group of inherited health conditions that affect the red blood cells. The most serious type is called sickle cell anaemia. Sickle cell disease is particularly common in people with an African or Caribbean family background. People with sickle cell disease produce unusually shaped red[…][nhs.uk]

  • Folate-Deficiency Anemia

    Folate-deficiency anemia frequently appears in women of childbearing age, in those who are pregnant or lactating, in alcohol abusers and malnourished individuals, thus proving the necessity of folate oral supplementation. Prevention must be carefully conducted, since the elderly may have difficulties tolerating folate[…][symptoma.com]

  • Vitamin B12 Deficiency

    The hematological changes in vitamin B12 deficiency present as megaloblastic anemia, increased lactate dehydrogenase, vasoconstriction, increased platelet aggregation, and[ncbi.nlm.nih.gov]

  • Hereditary Spherocytosis

    Reticulocytosis, increased bilirubin, increased lactate dehydrogenase, increased urinary and fecal urobilinogen, and decreased haptoglobin, reflect increased erythrocyte production[clinicaladvisor.com] FBC shows raised MCHC and increased red cell distribution width.[patient.info] Other biochemical changes of hemolysis also are also present, including: increased lactate dehydrogenase (LDH) increased unconjugated bilirubin decreased serum haptoglobin[steadyhealth.com]

  • Pernicious Anemia

    […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] […] decreased Average amount of hemoglobin in RBCs (mean corpuscular hemoglobin, MCH)—decreased Hemoglobin concentration (mean corpuscular hemoglobin concentration, MCHC)—decreased Increased[labtestsonline.org]

  • Immune Hemolytic Anemia

    Expected laboratory findings in AIHA include positive direct antiglobulin test (DAT), decreased haptoglobin, increased indirect bilirubin, increased lactate dehydrogenase[xpertdox.com] Increased serum unconjugated bilirubin, increased lactate dehydrogenase (LDH) and reduced or absent haptoglobin. Increased urinary urobilinogen, haemosiderinuria.[patient.info] The criteria for inclusion were a positive direct antiglobulin test and evidence of hemolysis that included reticulocytosis, increased indirect bilirubin, increased lactate[clincancerres.aacrjournals.org]

  • Cooley's Anemia

    […] and a decreasing trend in the serum lactate dehydrogenase (LDH) and serum unconjugated bilirubin levels.[onlinelibrary.wiley.com] blood cell distribution width High Normal; occasionally high Normal Ferritin Low Normal Normal Mentzer index for children (MCV/red blood cell count) 13 13 13 Hb electrophoresis[aafp.org] […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org]

  • Autoimmune Hemolytic Anemia

    Unconjugated bilirubin is usually, but not always, elevated and urine urobilinogen is increased. Lactate dehydrogenase is usually elevated into the thousands.[clinlabnavigator.com] […] variation in the size of RBCs (red cell distribution width, RDW) A blood smear may reveal RBCs that are smaller and paler than normal as well as RBCs that vary in size (anisocytosis[labtestsonline.org] Increased serum unconjugated bilirubin, increased lactate dehydrogenase (LDH) and reduced or absent haptoglobin. Increased urinary urobilinogen, haemosiderinuria.[patient.info]

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