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44 Possible Causes for Lactate Dehydrogenase Increased, Virus Associated Hemophagocytic Syndrome

  • Sickle Cell Disease

    If a person has sickle cell disease, it is present at birth. But most infants do not have any problems from the disease until they are about 5 or 6 months of age. Every state in the United States, the District of Columbia, and the U.S. territories require that all newborn babies receive screening for sickle cell[…][nhlbi.nih.gov]

  • Erythema Infectiosum

    Virus-associated hemophagocytic syndrome.[cmr.asm.org] Virus-associated hemophagocytic syndrome: a benign histiocytic proliferation distinct from malignant histiocytosis. Cancer 44 : 993 -1002. Rodis, J. F., A. F.[cmr.asm.org] Virus-associated hemophagocytic syndrome (VAHS) is characterized by histiocytic hyperplasia, marked hemophagocytosis, and cytopenia, in association with a systemic viral illness[cmr.asm.org]

  • Infectious Mononucleosis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] Epstein-Barr virus-associated hemophagocytic syndrome and fatal infectious mononucleosis. Am J Hematol. 1996 Oct. 53(2):111-5. [Medline].[emedicine.medscape.com] Epstein-Barr virus-induced infectious mononucleosis after two separate episodes of virus-associated hemophagocytic syndrome. Intern Med. 2009. 48(13):1169-73. [Medline].[emedicine.medscape.com]

  • Influenza Pneumonia

    Procalcitonin, C-reactive protein (CRP), and lactate dehydrogenase were markedly increased in patients with influenza pneumonia.[ncbi.nlm.nih.gov] Virus-associated hemophagocytic syndrome (VAHS) refers to hemophagocytic lymphohistiocytosis due to viral infection.[emcrit.org] The most consistent laboratory characteristics were increased lactate dehydrogenase level, a total leukocyte count within normal limits, lymphopenia, 13 and increased creatine[nejm.org]

  • Chronic Active Hepatitis

    Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] To our knowledge this is the first report of a hemophagocytic syndrome in that setting.[ncbi.nlm.nih.gov] The condition was interpreted as VAHS associated with chronic active hepatitis B and acute hepatitis C virus infection.[ncbi.nlm.nih.gov]

  • Viral Pneumonia

    Elevated lactate dehydrogenase, creatine phosphokinase, and creatinine at hospital admission may also serve as prognostic indicators of severe disease [ 14 ].[ccforum.biomedcentral.com] Virus-associated hemophagocytic syndrome may play an important role in development of multiorgan failure and ensuing death in H1N1 infection. [28] For more information on[emedicine.com] Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Crit Care. 2011 Mar 2. 15(2):R80. [Medline].[emedicine.medscape.com]

  • Lymphoma

    Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[emedicine.medscape.com]

  • Anicteric Viral Hepatitis

    hemophagocytic syndromes with emperipolesis may also be responsible for the decrease in platelet count seen during active infection. [10] There was no evidence of pancytopenia[mjdrdypu.org] […] destruction of platelets in the peripheral circulation secondary to circulating immune-complex deposits or anti-cardiolipin and anti-phospholipid antibodies. [7], [9], [11], [12] Virus-associated[mjdrdypu.org] […] infection. [11] Decreased platelet count has been attributed to various etiologies like bone marrow depression, secondary to disseminated intravascular coagulation (DIC), in association[mjdrdypu.org]

  • Precursor-Cell Lymphoblastic Leukemia

    Serum level of lactate dehydrogenase (LDH) predicts increased anaerobic glycolysis and is associated with metabolic modulation in cancer cells.[ncbi.nlm.nih.gov] Late-onset fatal Epstein-Barr virusassociated hemophagocytic syndrome following cord blood cell transplantation for adult acute lymphoblastic leukemia .[ajcp.oxfordjournals.org] Epstein-Barr virus associated hemophagocytic lymphohystiocytosis during maintenance treatment of acute lymphoblastic leukemia .[ajcp.oxfordjournals.org]

  • Hodgkin Lymphoma

    Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[emedicine.medscape.com]

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