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44 Possible Causes for Lactate Dehydrogenase Increased, Virus Associated Hemophagocytic Syndrome

  • Sickle Cell Disease

    If a person has sickle cell disease, it is present at birth. But most infants do not have any problems from the disease until they are about 5 or 6 months of age. Every state in the United States, the District of Columbia, and the U.S. territories require that all newborn babies receive screening for sickle cell[…][]

  • Erythema Infectiosum

    Virus-associated hemophagocytic syndrome.[] Virus-associated hemophagocytic syndrome: a benign histiocytic proliferation distinct from malignant histiocytosis. Cancer 44 : 993 -1002. Rodis, J. F., A. F.[] Virus-associated hemophagocytic syndrome (VAHS) is characterized by histiocytic hyperplasia, marked hemophagocytosis, and cytopenia, in association with a systemic viral illness[]

  • Infectious Mononucleosis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[] Epstein-Barr virus-associated hemophagocytic syndrome and fatal infectious mononucleosis. Am J Hematol. 1996 Oct. 53(2):111-5. [Medline].[] Epstein-Barr virus-induced infectious mononucleosis after two separate episodes of virus-associated hemophagocytic syndrome. Intern Med. 2009. 48(13):1169-73. [Medline].[]

  • Influenza Pneumonia

    Procalcitonin, C-reactive protein (CRP), and lactate dehydrogenase were markedly increased in patients with influenza pneumonia.[] Virus-associated hemophagocytic syndrome (VAHS) refers to hemophagocytic lymphohistiocytosis due to viral infection.[] The most consistent laboratory characteristics were increased lactate dehydrogenase level, a total leukocyte count within normal limits, lymphopenia, 13 and increased creatine[]

  • Chronic Active Hepatitis

    Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[] To our knowledge this is the first report of a hemophagocytic syndrome in that setting.[] The condition was interpreted as VAHS associated with chronic active hepatitis B and acute hepatitis C virus infection.[]

  • Viral Pneumonia

    Elevated lactate dehydrogenase, creatine phosphokinase, and creatinine at hospital admission may also serve as prognostic indicators of severe disease [ 14 ].[] Virus-associated hemophagocytic syndrome may play an important role in development of multiorgan failure and ensuing death in H1N1 infection. [28] For more information on[] Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Crit Care. 2011 Mar 2. 15(2):R80. [Medline].[]

  • Lymphoma

    Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[]

  • Anicteric Viral Hepatitis

    hemophagocytic syndromes with emperipolesis may also be responsible for the decrease in platelet count seen during active infection. [10] There was no evidence of pancytopenia[] […] destruction of platelets in the peripheral circulation secondary to circulating immune-complex deposits or anti-cardiolipin and anti-phospholipid antibodies. [7], [9], [11], [12] Virus-associated[] […] infection. [11] Decreased platelet count has been attributed to various etiologies like bone marrow depression, secondary to disseminated intravascular coagulation (DIC), in association[]

  • Precursor-Cell Lymphoblastic Leukemia

    Serum level of lactate dehydrogenase (LDH) predicts increased anaerobic glycolysis and is associated with metabolic modulation in cancer cells.[] Late-onset fatal Epstein-Barr virusassociated hemophagocytic syndrome following cord blood cell transplantation for adult acute lymphoblastic leukemia .[] Epstein-Barr virus associated hemophagocytic lymphohystiocytosis during maintenance treatment of acute lymphoblastic leukemia .[]

  • Hodgkin Lymphoma

    Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[]

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