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139 Possible Causes for Language Delays, Syndactyly of Second and Third Toes

  • Smith Lemli Opitz Syndrome

    An attempt to characterize the cognitive and behavioral phenotype of SLOS has identified increased rates of intellectual disability, language and motor developmental delay[ncbi.nlm.nih.gov] C. showing ambiguous genitalia and D. showing syndactyly of second and third toes.[indianpediatrics.net] It has been suggested that many individuals have a characteristic behavioral profile consisting of cognitive delays, hyperreactivity, irritability, language deficiency, and[disorders.eyes.arizona.edu]

  • Dubowitz Syndrome

    […] speech and language development Impaired speech development Language delay Language delayed Language development deficit Late-onset speech development Poor language development[rarediseases.info.nih.gov] The orthopedic manifestations of this condition primarily involve the hands and feet with brachyclinodactyly of the fifth finger and syndactyly of the second and third toes[ncbi.nlm.nih.gov] […] of second toes Brachyclinodactyly of fifth fingers Hair is sparse on lateral eyebrows Syndactyly of third toes Eye abnormalities Undescended testes Tapetoretinal degeneration[syndrome.org]

  • Autism

    We report a 9-year-old girl, referred to our department for her behavioural problems and language delay.[ncbi.nlm.nih.gov] […] the second and third toes, mild hypotonia, and autistic features.[web.archive.org] delay.[ncbi.nlm.nih.gov]

  • Smith-Magenis Syndrome

    […] and expressive language delays.[ncbi.nlm.nih.gov] Some cases also show limited elbow-extension span, clinodactyly of the fifth finger, syndactyly of the second and third toes, persistence of fetal pads, and polydactyly.[ojrd.biomedcentral.com] delays, psychomotor and growth retardation, and a 24-hour sleep disturbance.[ncbi.nlm.nih.gov]

  • Ring Chromosome 22

    Molecular characterisation of a ring chromosome 22 in a patient with severe language delay: a contribution to the refinement of the subtelomeric 22q deletion syndrome P De[jmg.bmj.com] delay: a contribution to the refinement of the subtelomeric 22q deletion syndrome. ( 11950869 ) De Mas P....Bieth E. 2002 20 Ring chromosome 22 and autism: report and review[malacards.org] Speech and language development is delayed. At three years the child begins to walk.[ncbi.nlm.nih.gov]

  • Sotos Syndrome

    Children with Sotos syndrome often experience developmental delays that may include motor and language delays, as well as mental retardation ranging from mild to severe.[disabled-world.com] […] of the second and third right toes.[ncbi.nlm.nih.gov] Mental Deficiency: (IQ 40-129) Mean IQ 78  Expressive language delay  Significant behavioral abnormalities (Due to difficulty in socializing) 8.[slideshare.net]

  • Crossed Polysyndactyly

    Brain atrophy Hypoplasia of the corpus callosum Infantile onset Pica Autosomal dominant inheritance Delayed speech and language development Microcephaly Wide nasal bridge[mendelian.co] The feet showed syndactyly involving second and third toes. The maternal second cousin also had the same deformity.[nature.com] In the feet, there is polydactyly of first toe and the first metacarpal is short and tibially deviated. Syndactyly of second and third toe (or all toes) is present.[myslide.es]

  • Wiedemann-Steiner Syndrome

    […] speech and language development Impaired speech development Language delay Language delayed Language development deficit Late-onset speech development Poor language development[rarediseases.info.nih.gov] Syndactyly is also noted in the feet and involves the second, third, and fourth toes. Fusion of the tarsal bones and an extra metatarsal have been noted.[emedicine.medscape.com] […] speech and language development Deficiency of speech development Delayed language development Delayed speech Delayed speech acquisition Delayed speech development Impaired[rarediseases.info.nih.gov]

  • Growth Failure

    His motor and personal skills were delayed and language delay and poor attention were noticed by the age of 3 years but subsequently improved. Figure 1. Growth chart.[academic.oup.com] Growth and skeletal asymmetry of the limbs manifested as hemihypertophy, clinodactyly of the fifth finger, syndactyly of second and third toes were also impartant criteria[medcraveonline.com] […] bone age, characteristic facial features, delayed language skills and usually normal motor development.[hormones.gr]

  • Chromosome 19q13.11 Deletion Syndrome

    […] speech and language development Impaired speech development Language delay Language delayed Language development deficit Late-onset speech development Poor language development[rarediseases.info.nih.gov] Moreover, second and third finger syndactyly of the right hand and bilateral two to four partial syndactyly of toes were present.[nature.com] Non verbal IQ, 56 O'Roak BJ, et al. (2012) pinto_10_ASD_discovery_cases-case5241_3 Average language (47%ile), no language delay, no epilepsy, right 2-3 toe syndactyly, right[gene.sfari.org]

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