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1 Possible Causes for largazole

  • Corneal Neovascularization

    In this study, we examined the effect of largazole, an inhibitor of class I HDACs, on inflammatory corneal angiogenesis.[ncbi.nlm.nih.gov] In a mouse model of alkali-induced corneal neovascularization (CNV), topical application of largazole to the injured corneas attenuated CNV.[ncbi.nlm.nih.gov] These data indicate that largazole has therapeutic potential for angiogenesis-associated diseases. Copyright 2014 Elsevier B.V. All rights reserved.[ncbi.nlm.nih.gov]

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